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The map label for this gene is htpG [H]

Identifier: 124023227

GI number: 124023227

Start: 1329134

End: 1331044

Strand: Direct

Name: htpG [H]

Synonym: P9303_15251

Alternate gene names: 124023227

Gene position: 1329134-1331044 (Clockwise)

Preceding gene: 124023226

Following gene: 124023228

Centisome position: 49.55

GC content: 45.37

Gene sequence:

>1911_bases
ATGACTGTGCTGGAAGAAGGTCAGATCCAGATTCACACCGAGAATATTTTCCCGATCATCAAGAAAGCCGTTTATTCCGG
CCACGAGGTTTTCTTGAGGGAGCTAGTCAGCAATGGCGTCGATGCAATAAGCAAAAGACGCATGGCAGCCATGGCAGGGG
ACTGCGCTGAAGGTGAAGAAGGAGTGATTGATATCAAGATTGACCGAGAAGCAAAGACACTCACTATTTCTGACAATGGA
ATCGGCATGACAACCGATGAAGTTAAGAAGTACATTAATCAGGTTGCCTTCTCAAGTGCAGAAGACTTCCTTGAAAAATA
CAAGCAGGAAAGTGACGGAATTATTGGTCACTTTGGGCTAGGTTTTTATTCTTCTTTCATGGTGTCGAAACATGTAGAGC
TAGTCACTAAGTCTGCTTGTTCCGAGAGTAAAGCTATTCGTTGGAGTTGTGATGGCTCGCCAAGATTTAATATCCAAGAG
GCCGAACGCAATGAAGCAGGAACCGATGTCATCCTTCATCTAATGGATGAAGAGTTGGAATACATCGAGCCAACTCGAAT
CCGTACTCTGATCACAAAATACTGTGACTTTATGCCTATTGAGGTAAAACTCGAAGGCGAATCAATTAATAAGCGAAATC
CACTTTGGAGGCGCAACCCAAGAGAAATCACTGATCAAGAGTATATCGAACTCTATAATTATCTATATCCATTCCAAGGT
GATCCTCTTCTATGGGTACACCTAAATACTGATTACCCCTATAACCTTCAAGGTATTCTCTATTTCCCTCGAATTGGTGG
TCGCGCAGATTGGGAAAAAGGTGAGATAAAACTCTACTGCAATCAAGTATTTGTCAGTGATTCAATTAAAGAAGTAGTAC
CACATTACCTCCTTCCGCTAAGAGGTGTGATCGACTCACCTGACATCCCACTTAATGTCAGTCGTAGCGCATTACAGACA
GACAGACGTGTTAGATCTATTGGCAATTTTGTTGCAAAGAAAGTTGCCGATCGCCTGCGAGGATTAAAGGCGGATCAACC
ACTTTTTTATGCTGAAGCATGGGATGCGTTAGCACCCTTCGTCAAAATAGGATCAATGGAAGATGAAAAGTTTGCTGATC
AAGTTGCCGATCTAATCATGTTTGGCACGACTGCTCTGGCTTCAACAGAAACAGATGGGGCCACTCCAGACCCAATTCCT
TGTGGCGAAAAAGCCTTTACTACGCTGAGTGGATACCAAAGTCGTCTGAGTACAGAAGCAAACAATCGCATTCTTTACTG
CACGGATGAAGTGGCCCAAGCGAGTGCCCTCAGCTTATGGACTTCACAGGGTGCTGAAATTCTTAAAACCGAAACGTTTA
TAGACAGCCAATTCCTCCCATGGCTTGAAGCTCGTCATAACGACCTCCGATTCCAGCGCGTTGATGCCGAACTGGATGAC
ACTCTTAAAGACGACAAACCTGAACTAACTGATCAGGAAGGAGAGACCAAGTCTGAAAGCCTGAGAACTCTAATGAAGCA
AGCACTAAATAACGACAAGGTGACCATTCAAGTACAAGCACTTAAGGGAGATAACGCACCTCCAGCAATGATTCTGCTGC
CAGAACAGATGCGACGTATGAACGACCTTGGAGCTCTCATGGATCAAAGGCTGCCAGGCCTTCCCGAGCATCATGTCCTT
CTTGTCAATCGTCGTCATCCACTTGTCGAAGGACTAGTGAAACTCAAATCTGGATCCGTGTTGGTCAGCACTTCAGGTGT
GTCTCCAACCGAAACCTTGGCACAAGGCTTAGCCCGTCACCTATACGACATGGCTCGCCTCGGTGTAGGAGGTTTGGAGC
CCAATGAACTTGCTGGATTCCAAAGCCGTAGTGCTGTGTTAATGGGACAGCTGATGGATCGGGCTTTTTAA

Upstream 100 bases:

>100_bases
AAGCAGCTGAGTTAATCACTAGGTACGGTCACCCCACCTAAAACCAGCTTGAGACCTGAGGCAAAGACTCCCTATGGTCA
AATCCTAAACAGGGAAACCA

Downstream 100 bases:

>100_bases
AGGAGGGGAGGATTTGATAAAATCTTAGTTTGGGTTCAGCGCCCTAGCTCTGTAGAGGATCAAGACATGTCCCGGGTGTG
TCAGCTCACTGGAACTCGCG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 636; Mature: 635

Protein sequence:

>636_residues
MTVLEEGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGVDAISKRRMAAMAGDCAEGEEGVIDIKIDREAKTLTISDNG
IGMTTDEVKKYINQVAFSSAEDFLEKYKQESDGIIGHFGLGFYSSFMVSKHVELVTKSACSESKAIRWSCDGSPRFNIQE
AERNEAGTDVILHLMDEELEYIEPTRIRTLITKYCDFMPIEVKLEGESINKRNPLWRRNPREITDQEYIELYNYLYPFQG
DPLLWVHLNTDYPYNLQGILYFPRIGGRADWEKGEIKLYCNQVFVSDSIKEVVPHYLLPLRGVIDSPDIPLNVSRSALQT
DRRVRSIGNFVAKKVADRLRGLKADQPLFYAEAWDALAPFVKIGSMEDEKFADQVADLIMFGTTALASTETDGATPDPIP
CGEKAFTTLSGYQSRLSTEANNRILYCTDEVAQASALSLWTSQGAEILKTETFIDSQFLPWLEARHNDLRFQRVDAELDD
TLKDDKPELTDQEGETKSESLRTLMKQALNNDKVTIQVQALKGDNAPPAMILLPEQMRRMNDLGALMDQRLPGLPEHHVL
LVNRRHPLVEGLVKLKSGSVLVSTSGVSPTETLAQGLARHLYDMARLGVGGLEPNELAGFQSRSAVLMGQLMDRAF

Sequences:

>Translated_636_residues
MTVLEEGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGVDAISKRRMAAMAGDCAEGEEGVIDIKIDREAKTLTISDNG
IGMTTDEVKKYINQVAFSSAEDFLEKYKQESDGIIGHFGLGFYSSFMVSKHVELVTKSACSESKAIRWSCDGSPRFNIQE
AERNEAGTDVILHLMDEELEYIEPTRIRTLITKYCDFMPIEVKLEGESINKRNPLWRRNPREITDQEYIELYNYLYPFQG
DPLLWVHLNTDYPYNLQGILYFPRIGGRADWEKGEIKLYCNQVFVSDSIKEVVPHYLLPLRGVIDSPDIPLNVSRSALQT
DRRVRSIGNFVAKKVADRLRGLKADQPLFYAEAWDALAPFVKIGSMEDEKFADQVADLIMFGTTALASTETDGATPDPIP
CGEKAFTTLSGYQSRLSTEANNRILYCTDEVAQASALSLWTSQGAEILKTETFIDSQFLPWLEARHNDLRFQRVDAELDD
TLKDDKPELTDQEGETKSESLRTLMKQALNNDKVTIQVQALKGDNAPPAMILLPEQMRRMNDLGALMDQRLPGLPEHHVL
LVNRRHPLVEGLVKLKSGSVLVSTSGVSPTETLAQGLARHLYDMARLGVGGLEPNELAGFQSRSAVLMGQLMDRAF
>Mature_635_residues
TVLEEGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGVDAISKRRMAAMAGDCAEGEEGVIDIKIDREAKTLTISDNGI
GMTTDEVKKYINQVAFSSAEDFLEKYKQESDGIIGHFGLGFYSSFMVSKHVELVTKSACSESKAIRWSCDGSPRFNIQEA
ERNEAGTDVILHLMDEELEYIEPTRIRTLITKYCDFMPIEVKLEGESINKRNPLWRRNPREITDQEYIELYNYLYPFQGD
PLLWVHLNTDYPYNLQGILYFPRIGGRADWEKGEIKLYCNQVFVSDSIKEVVPHYLLPLRGVIDSPDIPLNVSRSALQTD
RRVRSIGNFVAKKVADRLRGLKADQPLFYAEAWDALAPFVKIGSMEDEKFADQVADLIMFGTTALASTETDGATPDPIPC
GEKAFTTLSGYQSRLSTEANNRILYCTDEVAQASALSLWTSQGAEILKTETFIDSQFLPWLEARHNDLRFQRVDAELDDT
LKDDKPELTDQEGETKSESLRTLMKQALNNDKVTIQVQALKGDNAPPAMILLPEQMRRMNDLGALMDQRLPGLPEHHVLL
VNRRHPLVEGLVKLKSGSVLVSTSGVSPTETLAQGLARHLYDMARLGVGGLEPNELAGFQSRSAVLMGQLMDRAF

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=643, Percent_Identity=27.9937791601866, Blast_Score=233, Evalue=4e-61,
Organism=Homo sapiens, GI4507677, Length=652, Percent_Identity=24.8466257668712, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI153792590, Length=209, Percent_Identity=33.9712918660287, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI20149594, Length=204, Percent_Identity=34.8039215686275, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI154146191, Length=209, Percent_Identity=33.9712918660287, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1786679, Length=599, Percent_Identity=31.5525876460768, Blast_Score=250, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI115535205, Length=642, Percent_Identity=28.0373831775701, Blast_Score=234, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI115535167, Length=398, Percent_Identity=31.4070351758794, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17542208, Length=713, Percent_Identity=25.3856942496494, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17559162, Length=505, Percent_Identity=27.9207920792079, Blast_Score=191, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6323840, Length=598, Percent_Identity=27.9264214046823, Blast_Score=179, Evalue=9e-46,
Organism=Saccharomyces cerevisiae, GI6325016, Length=436, Percent_Identity=26.1467889908257, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24586016, Length=663, Percent_Identity=26.6968325791855, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI21357739, Length=648, Percent_Identity=26.5432098765432, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI17647529, Length=451, Percent_Identity=26.3858093126386, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71425; Mature: 71294

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLEEGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGVDAISKRRMAAMAGDCAEGEE
CCCCCCCEEEEEECHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCC
GVIDIKIDREAKTLTISDNGIGMTTDEVKKYINQVAFSSAEDFLEKYKQESDGIIGHFGL
CEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEHHH
GFYSSFMVSKHVELVTKSACSESKAIRWSCDGSPRFNIQEAERNEAGTDVILHLMDEELE
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHCCCCCHHHHHHHHHHHHH
YIEPTRIRTLITKYCDFMPIEVKLEGESINKRNPLWRRNPREITDQEYIELYNYLYPFQG
HCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
DPLLWVHLNTDYPYNLQGILYFPRIGGRADWEKGEIKLYCNQVFVSDSIKEVVPHYLLPL
CCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHH
RGVIDSPDIPLNVSRSALQTDRRVRSIGNFVAKKVADRLRGLKADQPLFYAEAWDALAPF
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
VKIGSMEDEKFADQVADLIMFGTTALASTETDGATPDPIPCGEKAFTTLSGYQSRLSTEA
HHHCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
NNRILYCTDEVAQASALSLWTSQGAEILKTETFIDSQFLPWLEARHNDLRFQRVDAELDD
CCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCHHHH
TLKDDKPELTDQEGETKSESLRTLMKQALNNDKVTIQVQALKGDNAPPAMILLPEQMRRM
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEECHHHHHHH
NDLGALMDQRLPGLPEHHVLLVNRRHPLVEGLVKLKSGSVLVSTSGVSPTETLAQGLARH
HHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
LYDMARLGVGGLEPNELAGFQSRSAVLMGQLMDRAF
HHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TVLEEGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGVDAISKRRMAAMAGDCAEGEE
CCCCCCEEEEEECHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCC
GVIDIKIDREAKTLTISDNGIGMTTDEVKKYINQVAFSSAEDFLEKYKQESDGIIGHFGL
CEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEHHH
GFYSSFMVSKHVELVTKSACSESKAIRWSCDGSPRFNIQEAERNEAGTDVILHLMDEELE
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHCCCCCHHHHHHHHHHHHH
YIEPTRIRTLITKYCDFMPIEVKLEGESINKRNPLWRRNPREITDQEYIELYNYLYPFQG
HCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
DPLLWVHLNTDYPYNLQGILYFPRIGGRADWEKGEIKLYCNQVFVSDSIKEVVPHYLLPL
CCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHH
RGVIDSPDIPLNVSRSALQTDRRVRSIGNFVAKKVADRLRGLKADQPLFYAEAWDALAPF
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
VKIGSMEDEKFADQVADLIMFGTTALASTETDGATPDPIPCGEKAFTTLSGYQSRLSTEA
HHHCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
NNRILYCTDEVAQASALSLWTSQGAEILKTETFIDSQFLPWLEARHNDLRFQRVDAELDD
CCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCHHHH
TLKDDKPELTDQEGETKSESLRTLMKQALNNDKVTIQVQALKGDNAPPAMILLPEQMRRM
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEECHHHHHHH
NDLGALMDQRLPGLPEHHVLLVNRRHPLVEGLVKLKSGSVLVSTSGVSPTETLAQGLARH
HHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
LYDMARLGVGGLEPNELAGFQSRSAVLMGQLMDRAF
HHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]