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The map label for this gene is dnaJ [H]

Identifier: 124023219

GI number: 124023219

Start: 1320214

End: 1321116

Strand: Reverse

Name: dnaJ [H]

Synonym: P9303_15171

Alternate gene names: 124023219

Gene position: 1321116-1320214 (Counterclockwise)

Preceding gene: 124023220

Following gene: 124023218

Centisome position: 49.25

GC content: 52.93

Gene sequence:

>903_bases
ATGACTTCTACCGCTAAACCGGATTACTGGTCTTTGCTAGGTGTCTCTCCAGACAGTGACGCCTCCCAGCTCAAAAGGGC
ATTTCGTCGCGAAGCACGACGATGGCATCCAGACCTCAATGGCAATGACAGCCACGCCGAGGAACGCTTCAAATTGGTTA
ATGAGGCCTATGCGGTTCTCAGTGATCCAAGACGTCGCGCTGCTTGGCAGGGATCGATGTCTACAGAGCAAGCCATTGCT
GATCCTTTCGCAGTTGGTTTTCCAACTTTCGATGAGTATCTCGAAGTGGTCCTTGGTTTGGAGCGCAAAGACGAACAGCC
TGGTGACGATGCTGATCCTTTCCCCTCAGAACAAGTCGACTGGCCTGCGACGTCTCCACCACCACCGCCTCCTCCTGTAC
AGGCCACTGATGATCTCGAGACGTTGGTCGAGTTGACCCCTGAGCAAGCCCTCTATGGAACTTCAGTGGATCTTGAACTC
GATGACGGCACTCTTGTAGAGGTTGATACACCGCCTTTGGCTGGCGATGGTTGGCGGTTACGTCTTGTGGGCGTAGCCCC
TGGAGGACGTGACCACTTCCTTCAGTTACGCGTTCAAACTGAAGACAGACTGAGGATTGACGGACTTCGTGTGCTTTATC
GCCTTGAGTTGTTTCCACCTGATGCAGCTCTTGGCTGTGCTGTGGATGTCCCAACTCTGTCTGGTCCTGTCACACTTCAA
GTGCCTCCAGCATCATCAAGTGGTCGTTTATTGCGCCTTCGCGGACGGGGACTTGAGCTTGATGGACGCAGGGGCGATCA
ATTGGTTGAAATTGTGGTGGTTATTCCTGCTGAACTTGCTGAAGCCGAACGAGCCCTCTACCGACGACTTCAAGAATTGG
CTCTTGATCCGGATAATCTATAA

Upstream 100 bases:

>100_bases
TTCTCAGATGATGACTGGGATGAAGATCCTTGGAATAGCCCTGCCCGGTCGTCCGACGGCCGACGCAGCTACAGGGGACG
TGAGCTAAATCCCTGGGACG

Downstream 100 bases:

>100_bases
AGCCGAATTAGATAATCAAGTGAGAGATCCCATCTGTCTGGCCTAATCCACATGCGCGTGTTTGTCCTTCTCTATGACGC
CGGTAAAGACAACGAGGGTA

Product: chaperone protein DnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTSTAKPDYWSLLGVSPDSDASQLKRAFRREARRWHPDLNGNDSHAEERFKLVNEAYAVLSDPRRRAAWQGSMSTEQAIA
DPFAVGFPTFDEYLEVVLGLERKDEQPGDDADPFPSEQVDWPATSPPPPPPPVQATDDLETLVELTPEQALYGTSVDLEL
DDGTLVEVDTPPLAGDGWRLRLVGVAPGGRDHFLQLRVQTEDRLRIDGLRVLYRLELFPPDAALGCAVDVPTLSGPVTLQ
VPPASSSGRLLRLRGRGLELDGRRGDQLVEIVVVIPAELAEAERALYRRLQELALDPDNL

Sequences:

>Translated_300_residues
MTSTAKPDYWSLLGVSPDSDASQLKRAFRREARRWHPDLNGNDSHAEERFKLVNEAYAVLSDPRRRAAWQGSMSTEQAIA
DPFAVGFPTFDEYLEVVLGLERKDEQPGDDADPFPSEQVDWPATSPPPPPPPVQATDDLETLVELTPEQALYGTSVDLEL
DDGTLVEVDTPPLAGDGWRLRLVGVAPGGRDHFLQLRVQTEDRLRIDGLRVLYRLELFPPDAALGCAVDVPTLSGPVTLQ
VPPASSSGRLLRLRGRGLELDGRRGDQLVEIVVVIPAELAEAERALYRRLQELALDPDNL
>Mature_299_residues
TSTAKPDYWSLLGVSPDSDASQLKRAFRREARRWHPDLNGNDSHAEERFKLVNEAYAVLSDPRRRAAWQGSMSTEQAIAD
PFAVGFPTFDEYLEVVLGLERKDEQPGDDADPFPSEQVDWPATSPPPPPPPVQATDDLETLVELTPEQALYGTSVDLELD
DGTLVEVDTPPLAGDGWRLRLVGVAPGGRDHFLQLRVQTEDRLRIDGLRVLYRLELFPPDAALGCAVDVPTLSGPVTLQV
PPASSSGRLLRLRGRGLELDGRRGDQLVEIVVVIPAELAEAERALYRRLQELALDPDNL

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI23503241, Length=131, Percent_Identity=35.1145038167939, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786197, Length=345, Percent_Identity=27.2463768115942, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787235, Length=299, Percent_Identity=28.0936454849498, Blast_Score=100, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17554644, Length=62, Percent_Identity=46.7741935483871, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C [H]

EC number: NA

Molecular weight: Translated: 33127; Mature: 32996

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTAKPDYWSLLGVSPDSDASQLKRAFRREARRWHPDLNGNDSHAEERFKLVNEAYAVL
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
SDPRRRAAWQGSMSTEQAIADPFAVGFPTFDEYLEVVLGLERKDEQPGDDADPFPSEQVD
CCHHHHHHHCCCCCHHHHHCCCHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
WPATSPPPPPPPVQATDDLETLVELTPEQALYGTSVDLELDDGTLVEVDTPPLAGDGWRL
CCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHCCCEEEEEECCCEEEEECCCCCCCCCEEE
RLVGVAPGGRDHFLQLRVQTEDRLRIDGLRVLYRLELFPPDAALGCAVDVPTLSGPVTLQ
EEEEECCCCCCEEEEEEECCCCCEEHHHEEEEEEEEECCCCCCCCEEEECCCCCCCEEEE
VPPASSSGRLLRLRGRGLELDGRRGDQLVEIVVVIPAELAEAERALYRRLQELALDPDNL
ECCCCCCCCEEEEECCCCEECCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSTAKPDYWSLLGVSPDSDASQLKRAFRREARRWHPDLNGNDSHAEERFKLVNEAYAVL
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
SDPRRRAAWQGSMSTEQAIADPFAVGFPTFDEYLEVVLGLERKDEQPGDDADPFPSEQVD
CCHHHHHHHCCCCCHHHHHCCCHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
WPATSPPPPPPPVQATDDLETLVELTPEQALYGTSVDLELDDGTLVEVDTPPLAGDGWRL
CCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHCCCEEEEEECCCEEEEECCCCCCCCCEEE
RLVGVAPGGRDHFLQLRVQTEDRLRIDGLRVLYRLELFPPDAALGCAVDVPTLSGPVTLQ
EEEEECCCCCCEEEEEEECCCCCEEHHHEEEEEEEEECCCCCCCCEEEECCCCCCCEEEE
VPPASSSGRLLRLRGRGLELDGRRGDQLVEIVVVIPAELAEAERALYRRLQELALDPDNL
ECCCCCCCCEEEEECCCCEECCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9240461; 8003021; 7811295 [H]