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The map label for this gene is aspC [H]

Identifier: 124023136

GI number: 124023136

Start: 1226544

End: 1227722

Strand: Reverse

Name: aspC [H]

Synonym: P9303_14321

Alternate gene names: 124023136

Gene position: 1227722-1226544 (Counterclockwise)

Preceding gene: 124023140

Following gene: 124023135

Centisome position: 45.76

GC content: 51.99

Gene sequence:

>1179_bases
ATGCCACTCCCGCCTCATCTTTCCGACCGAGTCGTTGCCCTTCAGCCCTCACTCACACTGGCAATCAGTGCTCGAGCAAA
GGCTCTTCAGCAAGAAGGCCGCGACATTTGCAGCATGAGTGCTGGTGAGCCGGATTTCAATACCCCTGAATTCATCATTG
ATGCCACGGTGAAGGCACTCCGTGATGGCATCACCCGTTATGGCCCTGCCGCTGGAGACCCTGAACTGCGTGAGGCAATA
GCCACCAAGCTCAGCAAAGAAAACACTGTGCCAACCAATGCAGAGCAAGTGTTGGTGACCAATGGAGGCAAGCAAGCAAT
CTTTAACTTGTTTCAGGTGATCCTCAATCCAGGCGATGAGGTTTTAATCCCTGCTCCTTATTGGCTGAGTTATCCAGAAA
TGGCCCGCTTAGCCGGTGCAAAGGTGACAACACTTCCCTCCACTCCAGAAAACGGTTTCTGTCTAGATCTCAACAACCTA
GAAGCTTCCATCGGCTCAAAAACCCGTCTGTTAATACTTAATTCCCCGGGCAACCCAACCGGTCGTGTGATGGCACGCAA
GGAGCTGGAAGCTTTGGCTGATCTGCTAAGAAATTATCCCCAGATCCTTGTCATGAGTGATGAGATCTACGAGTTCATTC
TTGAAGACGGGCAACAGCATCACAGCTTCTCTGCTATAGCACCAGATCTTTCAGACAGAACCTTCATCGTTAACGGCTTT
GCCAAGGGCTGGGCAATGACTGGTTGGCGGTTGGGTTATCTAGCCGGCCCCGCTCATGCAGTGAAAGCGGCCACTGCCCT
CCAAAGCCAGAGCACGAGCAATGTCTGCAGTTTCGCTCAGCGTGGAGCCTTGGCCGCGCTGCAAGGCTCAAGGGAGTGTG
TGAAGAAGATGGTTAATAGCTACAACACCCGACGCGAACTCCTCGCCTCTGGCTTGCTTGGCCTTGAAGGGATCAGCCTG
ATCTCTCCAAAAGGTGCGTTTTATGCCTTCCCAAAACTACCTGAAGGAAGCCTCGACTCAGTAAGTTTCTGTCAGCAAGC
TCTTGAAAACTATGGGCTTGCCATGGTTCCAGGTGCCGCATTCGGAGACGACAGTTGCATACGCCTCACTTGTGCTGTGT
CACATAAGACGATTTGCGATGGACTAGAACGTCTCCGCAAAGCTCTAAAACAGAGCTAA

Upstream 100 bases:

>100_bases
ATGACCTTTAAAAAGCCAATTGAAAGAAGTTGGTTGTCCATGTCAGAGCATCAGGCAAGATGTGATCCTTACGGGCATCC
CGCAAGGGGATGCGGCACCA

Downstream 100 bases:

>100_bases
AGACACAACACAACAAAGACAACATGCCTTCAAGACCAGACCGGGCGTTGGTCCTCACTGCATTGATCTGCTGCTTTGGT
TTACTGAGCTGCAGCAATCA

Product: aminotransferases class-I

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MPLPPHLSDRVVALQPSLTLAISARAKALQQEGRDICSMSAGEPDFNTPEFIIDATVKALRDGITRYGPAAGDPELREAI
ATKLSKENTVPTNAEQVLVTNGGKQAIFNLFQVILNPGDEVLIPAPYWLSYPEMARLAGAKVTTLPSTPENGFCLDLNNL
EASIGSKTRLLILNSPGNPTGRVMARKELEALADLLRNYPQILVMSDEIYEFILEDGQQHHSFSAIAPDLSDRTFIVNGF
AKGWAMTGWRLGYLAGPAHAVKAATALQSQSTSNVCSFAQRGALAALQGSRECVKKMVNSYNTRRELLASGLLGLEGISL
ISPKGAFYAFPKLPEGSLDSVSFCQQALENYGLAMVPGAAFGDDSCIRLTCAVSHKTICDGLERLRKALKQS

Sequences:

>Translated_392_residues
MPLPPHLSDRVVALQPSLTLAISARAKALQQEGRDICSMSAGEPDFNTPEFIIDATVKALRDGITRYGPAAGDPELREAI
ATKLSKENTVPTNAEQVLVTNGGKQAIFNLFQVILNPGDEVLIPAPYWLSYPEMARLAGAKVTTLPSTPENGFCLDLNNL
EASIGSKTRLLILNSPGNPTGRVMARKELEALADLLRNYPQILVMSDEIYEFILEDGQQHHSFSAIAPDLSDRTFIVNGF
AKGWAMTGWRLGYLAGPAHAVKAATALQSQSTSNVCSFAQRGALAALQGSRECVKKMVNSYNTRRELLASGLLGLEGISL
ISPKGAFYAFPKLPEGSLDSVSFCQQALENYGLAMVPGAAFGDDSCIRLTCAVSHKTICDGLERLRKALKQS
>Mature_391_residues
PLPPHLSDRVVALQPSLTLAISARAKALQQEGRDICSMSAGEPDFNTPEFIIDATVKALRDGITRYGPAAGDPELREAIA
TKLSKENTVPTNAEQVLVTNGGKQAIFNLFQVILNPGDEVLIPAPYWLSYPEMARLAGAKVTTLPSTPENGFCLDLNNLE
ASIGSKTRLLILNSPGNPTGRVMARKELEALADLLRNYPQILVMSDEIYEFILEDGQQHHSFSAIAPDLSDRTFIVNGFA
KGWAMTGWRLGYLAGPAHAVKAATALQSQSTSNVCSFAQRGALAALQGSRECVKKMVNSYNTRRELLASGLLGLEGISLI
SPKGAFYAFPKLPEGSLDSVSFCQQALENYGLAMVPGAAFGDDSCIRLTCAVSHKTICDGLERLRKALKQS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=397, Percent_Identity=28.463476070529, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI169881279, Length=397, Percent_Identity=28.463476070529, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI56713256, Length=391, Percent_Identity=28.6445012787724, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI56713254, Length=391, Percent_Identity=28.6445012787724, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI4507369, Length=390, Percent_Identity=25.6410256410256, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI169881281, Length=305, Percent_Identity=26.5573770491803, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI149944424, Length=323, Percent_Identity=26.625386996904, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI187936925, Length=357, Percent_Identity=25.4901960784314, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI14211921, Length=357, Percent_Identity=25.4901960784314, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI215599424, Length=396, Percent_Identity=22.979797979798, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI19263340, Length=396, Percent_Identity=22.979797979798, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI7705897, Length=382, Percent_Identity=23.0366492146597, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI33469970, Length=382, Percent_Identity=23.0366492146597, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786816, Length=378, Percent_Identity=29.3650793650794, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1788722, Length=385, Percent_Identity=29.3506493506493, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788627, Length=353, Percent_Identity=27.7620396600567, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1790797, Length=371, Percent_Identity=24.5283018867925, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787909, Length=197, Percent_Identity=27.4111675126904, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=346, Percent_Identity=27.1676300578035, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=404, Percent_Identity=25.7425742574257, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=404, Percent_Identity=25.7425742574257, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=251, Percent_Identity=29.0836653386454, Blast_Score=118, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6322401, Length=331, Percent_Identity=28.3987915407855, Blast_Score=119, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=340, Percent_Identity=24.1176470588235, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323118, Length=364, Percent_Identity=24.7252747252747, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573069, Length=354, Percent_Identity=25.4237288135593, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24646114, Length=354, Percent_Identity=25.4237288135593, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28573067, Length=354, Percent_Identity=25.4237288135593, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28573065, Length=354, Percent_Identity=25.4237288135593, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI18859735, Length=368, Percent_Identity=23.3695652173913, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45551451, Length=341, Percent_Identity=24.9266862170088, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24641770, Length=341, Percent_Identity=24.9266862170088, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641760, Length=341, Percent_Identity=24.9266862170088, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641768, Length=341, Percent_Identity=24.9266862170088, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641766, Length=341, Percent_Identity=24.9266862170088, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641764, Length=341, Percent_Identity=24.9266862170088, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21356535, Length=359, Percent_Identity=25.9052924791086, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42210; Mature: 42079

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPPHLSDRVVALQPSLTLAISARAKALQQEGRDICSMSAGEPDFNTPEFIIDATVKAL
CCCCCCCCCCEEEECCCEEEEEHHHHHHHHHHCHHHHCCCCCCCCCCCCHHHHHHHHHHH
RDGITRYGPAAGDPELREAIATKLSKENTVPTNAEQVLVTNGGKQAIFNLFQVILNPGDE
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCC
VLIPAPYWLSYPEMARLAGAKVTTLPSTPENGFCLDLNNLEASIGSKTRLLILNSPGNPT
EEECCCHHCCCHHHHHHCCCEEEECCCCCCCCEEEECCCCHHCCCCCEEEEEEECCCCCH
GRVMARKELEALADLLRNYPQILVMSDEIYEFILEDGQQHHSFSAIAPDLSDRTFIVNGF
HHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEEECC
AKGWAMTGWRLGYLAGPAHAVKAATALQSQSTSNVCSFAQRGALAALQGSRECVKKMVNS
CCCCCCCCEEEEHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHH
YNTRRELLASGLLGLEGISLISPKGAFYAFPKLPEGSLDSVSFCQQALENYGLAMVPGAA
CCHHHHHHHHHHHCCCCCEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHCCEEEECCCC
FGDDSCIRLTCAVSHKTICDGLERLRKALKQS
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLPPHLSDRVVALQPSLTLAISARAKALQQEGRDICSMSAGEPDFNTPEFIIDATVKAL
CCCCCCCCCEEEECCCEEEEEHHHHHHHHHHCHHHHCCCCCCCCCCCCHHHHHHHHHHH
RDGITRYGPAAGDPELREAIATKLSKENTVPTNAEQVLVTNGGKQAIFNLFQVILNPGDE
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCC
VLIPAPYWLSYPEMARLAGAKVTTLPSTPENGFCLDLNNLEASIGSKTRLLILNSPGNPT
EEECCCHHCCCHHHHHHCCCEEEECCCCCCCCEEEECCCCHHCCCCCEEEEEEECCCCCH
GRVMARKELEALADLLRNYPQILVMSDEIYEFILEDGQQHHSFSAIAPDLSDRTFIVNGF
HHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEEECC
AKGWAMTGWRLGYLAGPAHAVKAATALQSQSTSNVCSFAQRGALAALQGSRECVKKMVNS
CCCCCCCCEEEEHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHH
YNTRRELLASGLLGLEGISLISPKGAFYAFPKLPEGSLDSVSFCQQALENYGLAMVPGAA
CCHHHHHHHHHHHCCCCCEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHCCEEEECCCC
FGDDSCIRLTCAVSHKTICDGLERLRKALKQS
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]