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The map label for this gene is arsR [H]

Identifier: 124022811

GI number: 124022811

Start: 986976

End: 987254

Strand: Reverse

Name: arsR [H]

Synonym: P9303_11041

Alternate gene names: 124022811

Gene position: 987254-986976 (Counterclockwise)

Preceding gene: 124022814

Following gene: 124022810

Centisome position: 36.8

GC content: 45.52

Gene sequence:

>279_bases
ATGGGCACAACGATTGCCCCGCCACATTTGCTTGATTCAAGTCGTGCCAGAACTTTAATGAAGGCACTTGCAGATCCTAT
TCGTCTGCAAGTGATCGAGGAGCTTGCCTGTGGTGAACGTTGTGTGTGTGATCTTATTAATGAGTTAAGTCTTGGCCAAT
CACGCCTTTCCTTTCATCTCAAGGTCTTAAAAGATGCTGGTTTGATTGTTGATCGGCAGAGTGGTCGTTGGGTTTATTAC
CGCTTAGAGCCAAAAGCCCTTGGTATCTTGCAAGATTGA

Upstream 100 bases:

>100_bases
GGATCAATCAAAATATCTTGATGCATCAACCATAGTCGATATAAGCGCTCTTTCCCCTTTCTTATATTGTCCTTAAAGTA
AAAAACCTCTTCCATTAATC

Downstream 100 bases:

>100_bases
CTTTCATCTTTAGCCGAGCAATGCCAGAAACCAACGATTGACTGCGAGTAATGATGTTGTTGCTAGTCATGAGCCTGATC
AGCAGACCAAAGCAAAAGCC

Product: regulatory proteins, ArsR family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 92; Mature: 91

Protein sequence:

>92_residues
MGTTIAPPHLLDSSRARTLMKALADPIRLQVIEELACGERCVCDLINELSLGQSRLSFHLKVLKDAGLIVDRQSGRWVYY
RLEPKALGILQD

Sequences:

>Translated_92_residues
MGTTIAPPHLLDSSRARTLMKALADPIRLQVIEELACGERCVCDLINELSLGQSRLSFHLKVLKDAGLIVDRQSGRWVYY
RLEPKALGILQD
>Mature_91_residues
GTTIAPPHLLDSSRARTLMKALADPIRLQVIEELACGERCVCDLINELSLGQSRLSFHLKVLKDAGLIVDRQSGRWVYYR
LEPKALGILQD

Specific function: Transcriptional repressor for the arsEFG operon. ArsE is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsE is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=67, Percent_Identity=47.7611940298507, Blast_Score=65, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 10288; Mature: 10157

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTTIAPPHLLDSSRARTLMKALADPIRLQVIEELACGERCVCDLINELSLGQSRLSFHL
CCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHH
KVLKDAGLIVDRQSGRWVYYRLEPKALGILQD
HHHCCCCEEEECCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
GTTIAPPHLLDSSRARTLMKALADPIRLQVIEELACGERCVCDLINELSLGQSRLSFHL
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHH
KVLKDAGLIVDRQSGRWVYYRLEPKALGILQD
HHHCCCCEEEECCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721697; 8041620; 9278503 [H]