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The map label for this gene is 124022762

Identifier: 124022762

GI number: 124022762

Start: 953424

End: 953807

Strand: Direct

Name: 124022762

Synonym: P9303_10551

Alternate gene names: NA

Gene position: 953424-953807 (Clockwise)

Preceding gene: 124022761

Following gene: 124022765

Centisome position: 35.54

GC content: 51.3

Gene sequence:

>384_bases
ATGACCATTCCTGTGCTTCCAGCCGTTGTCACCTTGGCTGCCGCGATCGTCTACCAAGGAACCATGTTTGCTGTGGCATT
TGCACGTAGCCAGTACAAGGTAAAAGCTCCAGCAACGAGTGGGCCAGAAGAATTTGAGCGAGTGCTGCGTGTTCAGCAGA
ACACCCTTGAACAGATGATGTTTTTCCTGCCGGTGTTCTGGCTAGCCGCTCTTTCAAGCAACACATCTGTTGCCTGCTTG
ATTGGCTTCATCTGGGTGGGCGCACGTATTGCTTATGGCATTGGCTATTGGAAAGCGGCCAGTCTGAGAGGCCCAGGCTT
TGCCATTAGCCTGCTTGCCAGCGCAGTTCTTTTGGTGATGGCAATTGTTGGTCTATTTAACTAA

Upstream 100 bases:

>100_bases
CAAAGACTGCTCTTCATCAGAGAGGCACAGCCCCTCTCGCTGGTCATCAAGGCTGGAATTCAGATGGCATCCTTAAAGTC
ATTGTGCTGATACCAATTTC

Downstream 100 bases:

>100_bases
TATTTCGCGATCTTATAGGAAGCTTCAATCTGCAATATTGGCCTCTTCTGCCAGAAGTCAACACTCTGAGCTACGTTTGC
AGAGGCTGCGCACCTTTGGC

Product: MAPEG

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MTIPVLPAVVTLAAAIVYQGTMFAVAFARSQYKVKAPATSGPEEFERVLRVQQNTLEQMMFFLPVFWLAALSSNTSVACL
IGFIWVGARIAYGIGYWKAASLRGPGFAISLLASAVLLVMAIVGLFN

Sequences:

>Translated_127_residues
MTIPVLPAVVTLAAAIVYQGTMFAVAFARSQYKVKAPATSGPEEFERVLRVQQNTLEQMMFFLPVFWLAALSSNTSVACL
IGFIWVGARIAYGIGYWKAASLRGPGFAISLLASAVLLVMAIVGLFN
>Mature_126_residues
TIPVLPAVVTLAAAIVYQGTMFAVAFARSQYKVKAPATSGPEEFERVLRVQQNTLEQMMFFLPVFWLAALSSNTSVACLI
GFIWVGARIAYGIGYWKAASLRGPGFAISLLASAVLLVMAIVGLFN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MAPEG family [H]

Homologues:

Organism=Homo sapiens, GI4505181, Length=108, Percent_Identity=39.8148148148148, Blast_Score=65, Evalue=1e-11,
Organism=Homo sapiens, GI22035629, Length=100, Percent_Identity=37, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001129 [H]

Pfam domain/function: PF01124 MAPEG [H]

EC number: 2.5.1.18

Molecular weight: Translated: 13676; Mature: 13545

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPVLPAVVTLAAAIVYQGTMFAVAFARSQYKVKAPATSGPEEFERVLRVQQNTLEQMM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
FFLPVFWLAALSSNTSVACLIGFIWVGARIAYGIGYWKAASLRGPGFAISLLASAVLLVM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AIVGLFN
HHHHHCC
>Mature Secondary Structure 
TIPVLPAVVTLAAAIVYQGTMFAVAFARSQYKVKAPATSGPEEFERVLRVQQNTLEQMM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
FFLPVFWLAALSSNTSVACLIGFIWVGARIAYGIGYWKAASLRGPGFAISLLASAVLLVM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AIVGLFN
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]