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The map label for this gene is aspC [H]

Identifier: 124022748

GI number: 124022748

Start: 943988

End: 945193

Strand: Direct

Name: aspC [H]

Synonym: P9303_10411

Alternate gene names: 124022748

Gene position: 943988-945193 (Clockwise)

Preceding gene: 124022746

Following gene: 124022753

Centisome position: 35.19

GC content: 48.76

Gene sequence:

>1206_bases
TTGCCCTCAACCAAACACCCTCAACCTGGCACGAAGATCGATGCTGTGCTGGACCCTGTGATTCCAGAACTTAACGAGTT
GGTGGCGAAGACGCCAGGGACCCTTTCGCTGGCCCAGGGCATGGTGAATTGGGCTCCACCCGTTGCCGTAAAACTGGCAA
TGAACAATGCTCTGGTGAATCAAGAATCAAGCCTTAATCGTTATGGCCCGGTTCGAGGTGATCCCGCTTTGCTAGAGCTG
ATTAATCAAAAATTGATGATCCAAAACGGTTTGGATTTGGCCGAAAGCATGGTCATGGTCACTGCAGGTAGCAACATGGC
GTTTCATGCCATTGCTCAGGTTCTCTGTGATCCTGGCGATGAGGTCATTCTGCCGCTGCCTTATTACTTTAATCACTTTA
TGGCTATTCAGTTGGCCGGTGGAGTGCCTGTGCCTGTGGATGCTGGGTTAATACCTAACCCTGAGCTTATAGAGGCTGCG
ATTACAAAATGCACCCGTGCCATTGTCACGATAAGTCCTAATAACCCAAGCGGAATCGTTTTCCCTCAAACATTACTTGC
CGCCATCAATGGGATCTGTGCCCAGCATGGTTTGCTGCACATCAGCGATGAAGCCTATGAGGATTTTGTGTTTGGTGATG
TACCTCATTGGAGCCCTGGATCTATTCCTGGTGCAGGGAATCATACTGTTTCGCTCTATTCCTTCTCCAAGGCCTATGGC
ATGGCCGGATGGCGTCTTGGTTATATGTCAGCTCCTATTGGCTGGAGTAAGGCTTTGGCCAAGGTTCAAGATACAGTGCT
GATTTGCCCACCCCGTTTTTGCCAACAAGCAGCGATTGCGGCCTTGGCAGATGGTTCTGATTGGATGCGGCAGAATGTCT
CTCAATTCATGAGTCGATATCAGTATCTATTGAATCGTTTTGCCGCTAGCAACGATCGACCCTGGCGCTTTTTACATCAA
CCCAATGGAGCTTTTTATTGCTTGCTTGAAGTGGATTGTGGTTGCAATGGAGACACCTTGATGCGTCAGCTGGTAAGAGA
TTATCGAGTTGCCACGATTGGAGGTTGTAGTTTTGGTTTTAAGAACGAGAGTTGTGTGCTGCGCATCAGTGTGGGGATGC
TTGAAGGCGCTGAATTAATAGAAGCCTTTGATCGTTTGGAGGCAGGCTTGCTTAATGCAGTTCAAAAAGGAGTCCGTAAC
ACCTGA

Upstream 100 bases:

>100_bases
TCTTTTGGTAGGTCAATATCTTATGGATTTGGTGATTTGAGATTTCCATTCCATTCTGGTAAAAAATGGACGAACCTTTA
ACTCGATCGACGTGAACTCT

Downstream 100 bases:

>100_bases
ATAATAAAGTTAATTCCAATTTATTTTTTTATTTTTTTTGAAAAATAGCAATCAGCACTTGTCGAGTAATAATTGCGTGG
TGAATTTCGATCAGCTCTGT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MPSTKHPQPGTKIDAVLDPVIPELNELVAKTPGTLSLAQGMVNWAPPVAVKLAMNNALVNQESSLNRYGPVRGDPALLEL
INQKLMIQNGLDLAESMVMVTAGSNMAFHAIAQVLCDPGDEVILPLPYYFNHFMAIQLAGGVPVPVDAGLIPNPELIEAA
ITKCTRAIVTISPNNPSGIVFPQTLLAAINGICAQHGLLHISDEAYEDFVFGDVPHWSPGSIPGAGNHTVSLYSFSKAYG
MAGWRLGYMSAPIGWSKALAKVQDTVLICPPRFCQQAAIAALADGSDWMRQNVSQFMSRYQYLLNRFAASNDRPWRFLHQ
PNGAFYCLLEVDCGCNGDTLMRQLVRDYRVATIGGCSFGFKNESCVLRISVGMLEGAELIEAFDRLEAGLLNAVQKGVRN
T

Sequences:

>Translated_401_residues
MPSTKHPQPGTKIDAVLDPVIPELNELVAKTPGTLSLAQGMVNWAPPVAVKLAMNNALVNQESSLNRYGPVRGDPALLEL
INQKLMIQNGLDLAESMVMVTAGSNMAFHAIAQVLCDPGDEVILPLPYYFNHFMAIQLAGGVPVPVDAGLIPNPELIEAA
ITKCTRAIVTISPNNPSGIVFPQTLLAAINGICAQHGLLHISDEAYEDFVFGDVPHWSPGSIPGAGNHTVSLYSFSKAYG
MAGWRLGYMSAPIGWSKALAKVQDTVLICPPRFCQQAAIAALADGSDWMRQNVSQFMSRYQYLLNRFAASNDRPWRFLHQ
PNGAFYCLLEVDCGCNGDTLMRQLVRDYRVATIGGCSFGFKNESCVLRISVGMLEGAELIEAFDRLEAGLLNAVQKGVRN
T
>Mature_400_residues
PSTKHPQPGTKIDAVLDPVIPELNELVAKTPGTLSLAQGMVNWAPPVAVKLAMNNALVNQESSLNRYGPVRGDPALLELI
NQKLMIQNGLDLAESMVMVTAGSNMAFHAIAQVLCDPGDEVILPLPYYFNHFMAIQLAGGVPVPVDAGLIPNPELIEAAI
TKCTRAIVTISPNNPSGIVFPQTLLAAINGICAQHGLLHISDEAYEDFVFGDVPHWSPGSIPGAGNHTVSLYSFSKAYGM
AGWRLGYMSAPIGWSKALAKVQDTVLICPPRFCQQAAIAALADGSDWMRQNVSQFMSRYQYLLNRFAASNDRPWRFLHQP
NGAFYCLLEVDCGCNGDTLMRQLVRDYRVATIGGCSFGFKNESCVLRISVGMLEGAELIEAFDRLEAGLLNAVQKGVRNT

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=276, Percent_Identity=28.6231884057971, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI56713256, Length=276, Percent_Identity=28.6231884057971, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI95147551, Length=296, Percent_Identity=29.0540540540541, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI169881279, Length=296, Percent_Identity=29.0540540540541, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI169881281, Length=200, Percent_Identity=29.5, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1786816, Length=270, Percent_Identity=31.1111111111111, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788627, Length=298, Percent_Identity=26.1744966442953, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788722, Length=344, Percent_Identity=25.2906976744186, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994472, Length=284, Percent_Identity=26.4084507042254, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=284, Percent_Identity=26.4084507042254, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=294, Percent_Identity=26.530612244898, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=290, Percent_Identity=28.9655172413793, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323118, Length=340, Percent_Identity=22.6470588235294, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28573069, Length=253, Percent_Identity=28.4584980237154, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646114, Length=253, Percent_Identity=28.4584980237154, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573067, Length=253, Percent_Identity=28.4584980237154, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573065, Length=253, Percent_Identity=28.4584980237154, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43416; Mature: 43284

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSTKHPQPGTKIDAVLDPVIPELNELVAKTPGTLSLAQGMVNWAPPVAVKLAMNNALVN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEHHHHHHC
QESSLNRYGPVRGDPALLELINQKLMIQNGLDLAESMVMVTAGSNMAFHAIAQVLCDPGD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCEEEEEECCCHHHHHHHHHHHCCCC
EVILPLPYYFNHFMAIQLAGGVPVPVDAGLIPNPELIEAAITKCTRAIVTISPNNPSGIV
CEEEECHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCEE
FPQTLLAAINGICAQHGLLHISDEAYEDFVFGDVPHWSPGSIPGAGNHTVSLYSFSKAYG
HHHHHHHHHHHHHHHCCCEEECCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHC
MAGWRLGYMSAPIGWSKALAKVQDTVLICPPRFCQQAAIAALADGSDWMRQNVSQFMSRY
CCCEEEEEECCCCCHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QYLLNRFAASNDRPWRFLHQPNGAFYCLLEVDCGCNGDTLMRQLVRDYRVATIGGCSFGF
HHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCC
KNESCVLRISVGMLEGAELIEAFDRLEAGLLNAVQKGVRNT
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PSTKHPQPGTKIDAVLDPVIPELNELVAKTPGTLSLAQGMVNWAPPVAVKLAMNNALVN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEHHHHHHC
QESSLNRYGPVRGDPALLELINQKLMIQNGLDLAESMVMVTAGSNMAFHAIAQVLCDPGD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCEEEEEECCCHHHHHHHHHHHCCCC
EVILPLPYYFNHFMAIQLAGGVPVPVDAGLIPNPELIEAAITKCTRAIVTISPNNPSGIV
CEEEECHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCEE
FPQTLLAAINGICAQHGLLHISDEAYEDFVFGDVPHWSPGSIPGAGNHTVSLYSFSKAYG
HHHHHHHHHHHHHHHCCCEEECCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHC
MAGWRLGYMSAPIGWSKALAKVQDTVLICPPRFCQQAAIAALADGSDWMRQNVSQFMSRY
CCCEEEEEECCCCCHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QYLLNRFAASNDRPWRFLHQPNGAFYCLLEVDCGCNGDTLMRQLVRDYRVATIGGCSFGF
HHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCC
KNESCVLRISVGMLEGAELIEAFDRLEAGLLNAVQKGVRNT
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]