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The map label for this gene is sasA

Identifier: 124022652

GI number: 124022652

Start: 856880

End: 857992

Strand: Reverse

Name: sasA

Synonym: P9303_09431

Alternate gene names: 124022652

Gene position: 857992-856880 (Counterclockwise)

Preceding gene: 124022653

Following gene: 124022650

Centisome position: 31.98

GC content: 50.94

Gene sequence:

>1113_bases
GTGGATGGGGTCAAAGCCAATCAGCGACAACAGCTTCAGCTCCTGCTTGTAGCAGCTCGCCATCAGCTCTCCAGAAGCGA
TCTGCGATCAATGATCCAGTTTCTGGAGAATGAAGACTGCGGCTTCGATGTCACGCTGCAGATGGCTGATCCAAGTGAGC
AGCCGGAGTTGCTTGAACTACATCGACTAGTGGCAACCCCTGCACTGATCAAGCTATCGCCAACGCCAAAGCAAGTGTTC
GCAGGCAGCAGTATTTTCCAGCAACTACAAAACTGGATCACTCGCTGGCAGCAAGACATCGTCGTCACTGGCCTGGGCCT
GAGTTTGAGGCCAACAGAACTAGATGGCAGCCGCACTCAAAGGGAATTGCAACTGGAAGATCAGCTGCTGGTATTGCGCC
AGGAGAACGAAACCCTGATCGACCGCCTCAATGCACAGGAACGAACACTGAGAATGGTGGCTCATGAGTTAAGAACTCCT
CTAACTGCAGCAGTACTAGCGTTGCAGAGTCAACAGCTGGGTCAAATCAATATTGAACACTTTCAGGATGTCGTCAAACG
GCGTCTTGATGAAATCGAATTGCTATCAAAAGACCTGCTGGAAGTAAAAAGCACGAGATGGGAAGACCTGTTCAATCCAC
AAAATCTTGATCTAGGAAATATCGCCGCAGAAGCGATCCTAGAGCTCGAAAAGCTATGGCTTGATCGAAACATCGAGATC
CATACAGACATTCCCTCCGACCTACCCAAGGTATTTGCTGATCAGAGGCGCATGCGACAGGTGCTGCTCAACCTGCTGGA
AAATGCCCTGAAGTTCACTGAGGATGGTGGACAAGTTTCACTTTCCATGCTGCACCGCACAAGTCAATGGGTGCAGGTGA
GCATCTGTGACAACGGGCCAGGGATTCCAGAAGATGAGCAAGAGCGAATTTTTCTTGACCGAGTGCGCTTGCCACAAACT
TCAGTGACAACCTCTGGATTCGGAGTCGGCCTATCGGTATGCCGCCGCATCGTGGAGGTCCATGGGGGCAAAATCTGGGT
TGTCTCAGAACCCGACAAGGGCGCGTGCTTTTACTTAACAGTTCCAGTCTGGCAACGAAATGGACAAGAATGA

Upstream 100 bases:

>100_bases
GCCCACTGAGCAACAGACTGTTCATCAAGGTCTTAGCGGCTCTACCAGTTCAAGTAAAAACCCATAATGTGAACCTCAAC
CTTGCCAGGCACCCGCCACA

Downstream 100 bases:

>100_bases
ACTCCGCTTGCCTTGACGGAGGGTCAGGCTTAAACGTAGTTTTCCCGAGTGATCACAAGCACAGACAGCTGTGATTACGG
CCTCGCCCCCATCGTCTAGA

Product: adaptive-response sensory kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MDGVKANQRQQLQLLLVAARHQLSRSDLRSMIQFLENEDCGFDVTLQMADPSEQPELLELHRLVATPALIKLSPTPKQVF
AGSSIFQQLQNWITRWQQDIVVTGLGLSLRPTELDGSRTQRELQLEDQLLVLRQENETLIDRLNAQERTLRMVAHELRTP
LTAAVLALQSQQLGQINIEHFQDVVKRRLDEIELLSKDLLEVKSTRWEDLFNPQNLDLGNIAAEAILELEKLWLDRNIEI
HTDIPSDLPKVFADQRRMRQVLLNLLENALKFTEDGGQVSLSMLHRTSQWVQVSICDNGPGIPEDEQERIFLDRVRLPQT
SVTTSGFGVGLSVCRRIVEVHGGKIWVVSEPDKGACFYLTVPVWQRNGQE

Sequences:

>Translated_370_residues
MDGVKANQRQQLQLLLVAARHQLSRSDLRSMIQFLENEDCGFDVTLQMADPSEQPELLELHRLVATPALIKLSPTPKQVF
AGSSIFQQLQNWITRWQQDIVVTGLGLSLRPTELDGSRTQRELQLEDQLLVLRQENETLIDRLNAQERTLRMVAHELRTP
LTAAVLALQSQQLGQINIEHFQDVVKRRLDEIELLSKDLLEVKSTRWEDLFNPQNLDLGNIAAEAILELEKLWLDRNIEI
HTDIPSDLPKVFADQRRMRQVLLNLLENALKFTEDGGQVSLSMLHRTSQWVQVSICDNGPGIPEDEQERIFLDRVRLPQT
SVTTSGFGVGLSVCRRIVEVHGGKIWVVSEPDKGACFYLTVPVWQRNGQE
>Mature_370_residues
MDGVKANQRQQLQLLLVAARHQLSRSDLRSMIQFLENEDCGFDVTLQMADPSEQPELLELHRLVATPALIKLSPTPKQVF
AGSSIFQQLQNWITRWQQDIVVTGLGLSLRPTELDGSRTQRELQLEDQLLVLRQENETLIDRLNAQERTLRMVAHELRTP
LTAAVLALQSQQLGQINIEHFQDVVKRRLDEIELLSKDLLEVKSTRWEDLFNPQNLDLGNIAAEAILELEKLWLDRNIEI
HTDIPSDLPKVFADQRRMRQVLLNLLENALKFTEDGGQVSLSMLHRTSQWVQVSICDNGPGIPEDEQERIFLDRVRLPQT
SVTTSGFGVGLSVCRRIVEVHGGKIWVVSEPDKGACFYLTVPVWQRNGQE

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=30.316742081448, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=28.8888888888889, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=31.3364055299539, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=29.2181069958848, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=27.8225806451613, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789149, Length=220, Percent_Identity=29.5454545454545, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081816, Length=129, Percent_Identity=37.984496124031, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790300, Length=228, Percent_Identity=28.5087719298246, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=28.3333333333333, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=25.78125, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787894, Length=239, Percent_Identity=27.6150627615063, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786783, Length=279, Percent_Identity=27.2401433691756, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788279, Length=229, Percent_Identity=25.764192139738, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082128, Length=220, Percent_Identity=25, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1787374, Length=205, Percent_Identity=26.3414634146341, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SASA_PROM3 (A2C884)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016959.1
- ProteinModelPortal:   A2C884
- SMR:   A2C884
- STRING:   A2C884
- GeneID:   4776671
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_09431
- eggNOG:   COG0642
- HOGENOM:   HBG284956
- OMA:   IYSEAPL
- ProtClustDB:   PRK09303
- GO:   GO:0016020
- HAMAP:   MF_01837
- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.30.565.10
- Gene3D:   G3DSA:3.40.30.10
- PRINTS:   PR00344
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim; SSF52833 Thiordxn-like_fd

EC number: 2.7.3.- [C]

Molecular weight: Translated: 42225; Mature: 42225

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGVKANQRQQLQLLLVAARHQLSRSDLRSMIQFLENEDCGFDVTLQMADPSEQPELLEL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHH
HRLVATPALIKLSPTPKQVFAGSSIFQQLQNWITRWQQDIVVTGLGLSLRPTELDGSRTQ
HHHHHCCCEEEECCCHHHHHCCHHHHHHHHHHHHHHHHCEEEEECCCEECCCCCCCCHHH
RELQLEDQLLVLRQENETLIDRLNAQERTLRMVAHELRTPLTAAVLALQSQQLGQINIEH
HHHHHHCCEEEEECCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHH
FQDVVKRRLDEIELLSKDLLEVKSTRWEDLFNPQNLDLGNIAAEAILELEKLWLDRNIEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
HTDIPSDLPKVFADQRRMRQVLLNLLENALKFTEDGGQVSLSMLHRTSQWVQVSICDNGP
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCEEEEEEECCCC
GIPEDEQERIFLDRVRLPQTSVTTSGFGVGLSVCRRIVEVHGGKIWVVSEPDKGACFYLT
CCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEE
VPVWQRNGQE
EEHCCCCCCC
>Mature Secondary Structure
MDGVKANQRQQLQLLLVAARHQLSRSDLRSMIQFLENEDCGFDVTLQMADPSEQPELLEL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHH
HRLVATPALIKLSPTPKQVFAGSSIFQQLQNWITRWQQDIVVTGLGLSLRPTELDGSRTQ
HHHHHCCCEEEECCCHHHHHCCHHHHHHHHHHHHHHHHCEEEEECCCEECCCCCCCCHHH
RELQLEDQLLVLRQENETLIDRLNAQERTLRMVAHELRTPLTAAVLALQSQQLGQINIEH
HHHHHHCCEEEEECCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHH
FQDVVKRRLDEIELLSKDLLEVKSTRWEDLFNPQNLDLGNIAAEAILELEKLWLDRNIEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
HTDIPSDLPKVFADQRRMRQVLLNLLENALKFTEDGGQVSLSMLHRTSQWVQVSICDNGP
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCEEEEEEECCCC
GIPEDEQERIFLDRVRLPQTSVTTSGFGVGLSVCRRIVEVHGGKIWVVSEPDKGACFYLT
CCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEE
VPVWQRNGQE
EEHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA