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The map label for this gene is engD [H]

Identifier: 124022580

GI number: 124022580

Start: 791695

End: 792822

Strand: Direct

Name: engD [H]

Synonym: P9303_08711

Alternate gene names: 124022580

Gene position: 791695-792822 (Clockwise)

Preceding gene: 124022575

Following gene: 124022581

Centisome position: 29.51

GC content: 52.66

Gene sequence:

>1128_bases
ATGGTTTCTGGCATGGGCACGGCTAGATTTGCCCCCATGCTTAAAGCCGGAATTGTTGGACTACCAAATGTGGGTAAGTC
CACTCTTTTCAATGCACTTGTGGCCAACGCGCAGGCTCAAGCTGCCAACTTTCCCTTCTGCACCATTGAACCGAATGTGG
GCAGCGTTGCGGTACCTGATGAGCGCTTGCAGCTGCTTTGCGATCTAAGCAAGAGCAAGGAGCTGATTCCAACGCGCATG
GAGTTTGTTGATATCGCTGGTTTGGTCAAGGGGGCTAGTGAGGGAGAGGGGTTGGGCAACAAATTTCTTGCCAATATTCG
CGAGGTTGACGCCATCGTGCATGTGGTGCGTTGCTTTGAAGACGAGGATGTGATCCATGTCTCTGGATCAGTGGACCCTT
CTAGGGATGCTGAGGTCATCAACCTTGAACTCGGCTTTGCTGATCTCAGTCAGATCGAGAAACGGCGCTTGCGCTTGAAA
AAACAGACGCGCACAAGCAATGACGCCCAGCTCGAAGATGCTGCGCTTGAGCGGATTCAATCTGTGCTTGAGCAAGGTGG
TGCTGCTCGTGCTGTAGAGCTCAGTGATGAAGAAGCAAAGATGATTAAACCGCTTGGCCTGCTAACGGCTAAGCCAATCA
TTTACGCCACCAATGTGAGCGAAGACGATCTTGCCGGCGGCAATGCCTACTGTGAGGAGGTGACCAGCTTGGCGACGCGT
GAGGATGCTGAATGCGTGCGTATTTCAGCCCAGGTGGAGGCTGAGTTAATTGAACTCGGCGAAGCAGAGCGTATTGATTA
CCTTGAAGGCCTCGGAGTGAGTGAGGGGGGGCTGAAGAGTTTGATCAAGGCGACCTATCGGCTTCTAGGTCTTCGTACCT
ACTTCACTACAGGGGAGAAGGAAACCCGTGCTTGGACGTTTAAGGCCGGTATGACGGCTCCGCAGACAGCTGGTGTGATC
CATACTGACTTCGAGCGTGGTTTCATACGTGCTCAAACCATTGCTTACCAGAAGTTGCTTGAGGCCGGTTCCTTTGCTGA
AGCACGCAACAAGGGCTGGCTGCGTAGTGAGGGTAAGGACTACGTCGTAGCGGAGGGTGATGTTATGGAGTTCCTCTTTA
ACGTATAA

Upstream 100 bases:

>100_bases
CAGCAGTCTCGCTGGTCAGCGTGCCTGACTGCAGCAAGGCACGATCACGTAACTGCTAAGTGTCTTTAGCGTTGTTTTGC
GGTGCCATATCGCTTTTGCA

Downstream 100 bases:

>100_bases
GCGTCCAGTCATAGCAGGGGTTCTCAAAGGTTAGGAGAGGTGCTATTCTAACTTTTGCAGCTTAAATTTTGTTTTTAGAC
AACCATGCTTAATGGTTCTA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MVSGMGTARFAPMLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVAVPDERLQLLCDLSKSKELIPTRM
EFVDIAGLVKGASEGEGLGNKFLANIREVDAIVHVVRCFEDEDVIHVSGSVDPSRDAEVINLELGFADLSQIEKRRLRLK
KQTRTSNDAQLEDAALERIQSVLEQGGAARAVELSDEEAKMIKPLGLLTAKPIIYATNVSEDDLAGGNAYCEEVTSLATR
EDAECVRISAQVEAELIELGEAERIDYLEGLGVSEGGLKSLIKATYRLLGLRTYFTTGEKETRAWTFKAGMTAPQTAGVI
HTDFERGFIRAQTIAYQKLLEAGSFAEARNKGWLRSEGKDYVVAEGDVMEFLFNV

Sequences:

>Translated_375_residues
MVSGMGTARFAPMLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVAVPDERLQLLCDLSKSKELIPTRM
EFVDIAGLVKGASEGEGLGNKFLANIREVDAIVHVVRCFEDEDVIHVSGSVDPSRDAEVINLELGFADLSQIEKRRLRLK
KQTRTSNDAQLEDAALERIQSVLEQGGAARAVELSDEEAKMIKPLGLLTAKPIIYATNVSEDDLAGGNAYCEEVTSLATR
EDAECVRISAQVEAELIELGEAERIDYLEGLGVSEGGLKSLIKATYRLLGLRTYFTTGEKETRAWTFKAGMTAPQTAGVI
HTDFERGFIRAQTIAYQKLLEAGSFAEARNKGWLRSEGKDYVVAEGDVMEFLFNV
>Mature_375_residues
MVSGMGTARFAPMLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVAVPDERLQLLCDLSKSKELIPTRM
EFVDIAGLVKGASEGEGLGNKFLANIREVDAIVHVVRCFEDEDVIHVSGSVDPSRDAEVINLELGFADLSQIEKRRLRLK
KQTRTSNDAQLEDAALERIQSVLEQGGAARAVELSDEEAKMIKPLGLLTAKPIIYATNVSEDDLAGGNAYCEEVTSLATR
EDAECVRISAQVEAELIELGEAERIDYLEGLGVSEGGLKSLIKATYRLLGLRTYFTTGEKETRAWTFKAGMTAPQTAGVI
HTDFERGFIRAQTIAYQKLLEAGSFAEARNKGWLRSEGKDYVVAEGDVMEFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=373, Percent_Identity=42.8954423592493, Blast_Score=290, Evalue=2e-78,
Organism=Homo sapiens, GI58761502, Length=197, Percent_Identity=36.0406091370558, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=54.2699724517906, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1789574, Length=128, Percent_Identity=32.03125, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=371, Percent_Identity=42.3180592991914, Blast_Score=286, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6319499, Length=368, Percent_Identity=37.5, Blast_Score=230, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6321773, Length=378, Percent_Identity=33.8624338624339, Blast_Score=199, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6321649, Length=153, Percent_Identity=41.1764705882353, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640873, Length=372, Percent_Identity=40.3225806451613, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI24640877, Length=372, Percent_Identity=40.3225806451613, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI24640875, Length=372, Percent_Identity=40.3225806451613, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI24640879, Length=325, Percent_Identity=37.5384615384615, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24585318, Length=142, Percent_Identity=33.0985915492958, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40740; Mature: 40740

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSGMGTARFAPMLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVAVPD
CCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHCCCCEEEECCCCCCEECCH
ERLQLLCDLSKSKELIPTRMEFVDIAGLVKGASEGEGLGNKFLANIREVDAIVHVVRCFE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DEDVIHVSGSVDPSRDAEVINLELGFADLSQIEKRRLRLKKQTRTSNDAQLEDAALERIQ
CCCEEEEECCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
SVLEQGGAARAVELSDEEAKMIKPLGLLTAKPIIYATNVSEDDLAGGNAYCEEVTSLATR
HHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHC
EDAECVRISAQVEAELIELGEAERIDYLEGLGVSEGGLKSLIKATYRLLGLRTYFTTGEK
CCCHHEEEHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCCC
ETRAWTFKAGMTAPQTAGVIHTDFERGFIRAQTIAYQKLLEAGSFAEARNKGWLRSEGKD
CCEEEEEECCCCCCCCCCCEEECHHCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCC
YVVAEGDVMEFLFNV
EEEECCHHHHHHHCC
>Mature Secondary Structure
MVSGMGTARFAPMLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVAVPD
CCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHCCCCEEEECCCCCCEECCH
ERLQLLCDLSKSKELIPTRMEFVDIAGLVKGASEGEGLGNKFLANIREVDAIVHVVRCFE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DEDVIHVSGSVDPSRDAEVINLELGFADLSQIEKRRLRLKKQTRTSNDAQLEDAALERIQ
CCCEEEEECCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
SVLEQGGAARAVELSDEEAKMIKPLGLLTAKPIIYATNVSEDDLAGGNAYCEEVTSLATR
HHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHC
EDAECVRISAQVEAELIELGEAERIDYLEGLGVSEGGLKSLIKATYRLLGLRTYFTTGEK
CCCHHEEEHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCCC
ETRAWTFKAGMTAPQTAGVIHTDFERGFIRAQTIAYQKLLEAGSFAEARNKGWLRSEGKD
CCEEEEEECCCCCCCCCCCEEECHHCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCC
YVVAEGDVMEFLFNV
EEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]