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The map label for this gene is frr [H]

Identifier: 124022470

GI number: 124022470

Start: 701080

End: 701601

Strand: Reverse

Name: frr [H]

Synonym: P9303_07611

Alternate gene names: 124022470

Gene position: 701601-701080 (Counterclockwise)

Preceding gene: 124022471

Following gene: 124022469

Centisome position: 26.15

GC content: 47.89

Gene sequence:

>522_bases
ATGCACAAATCAGTGGAGGCCACACAACGCAACTTCGCCACCATCCGTACTGGACGCGCCAACCCGTCACTACTGGATCG
AATCAACGTTGAGTATTACGGCACCGAAACGCCCCTGAAATCTCTAGCAACAATATCCACCCCTGATTCACAGACGATTG
CCATACAGCCCTTTGACAATGGATCAATGGGCCTGATTGAAAAAGCCATTGCCACTAGTGATTTGGGCTTGACACCCAAC
AATGACGGCAAGATCATTCGCATCAATGTGCCGCCGCTAACTGAAGAGCGCCGCAAAGAGTTCTGCAAGCTGGCAGCAAA
ATATGCAGAGGAAGGCAAAGTAGCCCTGCGCAACATCCGTCGCGATGCAATTGATAAAGTGAAAAAGCTAGAAAAAGATG
CTGAGCTCTCTAAAGATCAGAGCCATGATGAACAGGATGGGATACAAAAACTCACCGACACATTCATCACTGAAATCGAA
AAATACCTCGCCGAAAAAGAAGCCGACATTCTCAAGGTTTGA

Upstream 100 bases:

>100_bases
CCCGTATCAGCAATGCAACCTAAACAGGCCATCCCAACTCATCCCTTCACCCAGCCTTCGCCTCTCTGAAGCCATGTCGA
ACCAGGATCTCAAAGACAAC

Downstream 100 bases:

>100_bases
GCACTCGAGATGTGCTGGTCATCGGAGCAGGCGCCGCTGGATCTGCGGCGGCTTTCCATCTGGCTGCAGCCGGCCAACGC
GTCACACTGCTCGAACAGAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MHKSVEATQRNFATIRTGRANPSLLDRINVEYYGTETPLKSLATISTPDSQTIAIQPFDNGSMGLIEKAIATSDLGLTPN
NDGKIIRINVPPLTEERRKEFCKLAAKYAEEGKVALRNIRRDAIDKVKKLEKDAELSKDQSHDEQDGIQKLTDTFITEIE
KYLAEKEADILKV

Sequences:

>Translated_173_residues
MHKSVEATQRNFATIRTGRANPSLLDRINVEYYGTETPLKSLATISTPDSQTIAIQPFDNGSMGLIEKAIATSDLGLTPN
NDGKIIRINVPPLTEERRKEFCKLAAKYAEEGKVALRNIRRDAIDKVKKLEKDAELSKDQSHDEQDGIQKLTDTFITEIE
KYLAEKEADILKV
>Mature_173_residues
MHKSVEATQRNFATIRTGRANPSLLDRINVEYYGTETPLKSLATISTPDSQTIAIQPFDNGSMGLIEKAIATSDLGLTPN
NDGKIIRINVPPLTEERRKEFCKLAAKYAEEGKVALRNIRRDAIDKVKKLEKDAELSKDQSHDEQDGIQKLTDTFITEIE
KYLAEKEADILKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=173, Percent_Identity=30.0578034682081, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI1786368, Length=172, Percent_Identity=54.0697674418605, Blast_Score=183, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24661488, Length=172, Percent_Identity=29.6511627906977, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 19388; Mature: 19388

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKSVEATQRNFATIRTGRANPSLLDRINVEYYGTETPLKSLATISTPDSQTIAIQPFDN
CCCCHHHHHHHHHHEECCCCCHHHHHHCCCEEECCCCCHHHHHCCCCCCCCEEEEEECCC
GSMGLIEKAIATSDLGLTPNNDGKIIRINVPPLTEERRKEFCKLAAKYAEEGKVALRNIR
CCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
RDAIDKVKKLEKDAELSKDQSHDEQDGIQKLTDTFITEIEKYLAEKEADILKV
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHKSVEATQRNFATIRTGRANPSLLDRINVEYYGTETPLKSLATISTPDSQTIAIQPFDN
CCCCHHHHHHHHHHEECCCCCHHHHHHCCCEEECCCCCHHHHHCCCCCCCCEEEEEECCC
GSMGLIEKAIATSDLGLTPNNDGKIIRINVPPLTEERRKEFCKLAAKYAEEGKVALRNIR
CCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
RDAIDKVKKLEKDAELSKDQSHDEQDGIQKLTDTFITEIEKYLAEKEADILKV
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]