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The map label for this gene is lepB2 [H]

Identifier: 124022460

GI number: 124022460

Start: 690246

End: 690950

Strand: Direct

Name: lepB2 [H]

Synonym: P9303_07511

Alternate gene names: 124022460

Gene position: 690246-690950 (Clockwise)

Preceding gene: 124022457

Following gene: 124022463

Centisome position: 25.73

GC content: 51.21

Gene sequence:

>705_bases
TTGTCTGACGCGCAGCAGCAGGACCATCCCACAAACGATAAGGCGTCTGCTCCCCAGGGAGCATCAACCTCTAAACCTCA
TCCATTTTGGGATTTCTGGGGACCAGTCTTCTTCACTTTGGGCCTGTATTTCGGCATTCGTCATTACGTCGCTGAGGCGA
GATACATTCCCTCTGAATCGATGATCCCAGGGCTGCAAGTCCAGGATCGTTTGCTGGTTGAGAAAGTCAGCCTTCGCAGT
CGATCTCCACGTCGTGGGGAGATCGTGGTATTTAACACGCCCTATTCCTTTAATTCTGCGTTGAATTTGAAGAGTGGTCA
GAGTGCCCTTCCTTGCTTTGTGGTGAACCTTCCTTTTATGAACTGGATTGGACTAACCAATCCCAGCTGTGATGCTTGGA
TTAAGCGTGTTGTCGCCGTGGGGGGAGACCAGGTTTCGATCAATCCCAGGGGAGAAGTGAGCGTGAATGGACAGAGGCTG
AAGGAGCCCTATGTAACCCAGTATTGCCCTGTGAACAACAGGGGAATGGGACCTTGCAATTCCCTGATCGCGACAGTTCC
CAGCGATCATGTCTTGGTGCTGGGAGATAACCGAAGCAATAGCACTGATGGACGAATTTGGGGATTTCTGCCTGAGAAAG
AGATCCTCGGGCGTGCCTTATGGCGTTTTTGGCCTTTTGATCGTTTCGGCTCACTTATTCCCTGA

Upstream 100 bases:

>100_bases
GCCAGCGGGGACGCACCATGGGCTGAGGTTGCTTTGATCACGCTAAGGGGCCGGACAGGCTGGCCTTATCGTTAATCATC
GAATTCATAACAGGGCTGAG

Downstream 100 bases:

>100_bases
GTCCACATGCCACGACACGGCCTTGCAGTTGGCAGCCCTGCCAGGGTTGATTAGCGGCTTTGGGGGCATGATCACTGTGC
CGATCTTGGATCCAGAGCTG

Product: Signal peptidase I

Products: NA

Alternate protein names: SPase I-2; Leader peptidase I-2 [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSDAQQQDHPTNDKASAPQGASTSKPHPFWDFWGPVFFTLGLYFGIRHYVAEARYIPSESMIPGLQVQDRLLVEKVSLRS
RSPRRGEIVVFNTPYSFNSALNLKSGQSALPCFVVNLPFMNWIGLTNPSCDAWIKRVVAVGGDQVSINPRGEVSVNGQRL
KEPYVTQYCPVNNRGMGPCNSLIATVPSDHVLVLGDNRSNSTDGRIWGFLPEKEILGRALWRFWPFDRFGSLIP

Sequences:

>Translated_234_residues
MSDAQQQDHPTNDKASAPQGASTSKPHPFWDFWGPVFFTLGLYFGIRHYVAEARYIPSESMIPGLQVQDRLLVEKVSLRS
RSPRRGEIVVFNTPYSFNSALNLKSGQSALPCFVVNLPFMNWIGLTNPSCDAWIKRVVAVGGDQVSINPRGEVSVNGQRL
KEPYVTQYCPVNNRGMGPCNSLIATVPSDHVLVLGDNRSNSTDGRIWGFLPEKEILGRALWRFWPFDRFGSLIP
>Mature_233_residues
SDAQQQDHPTNDKASAPQGASTSKPHPFWDFWGPVFFTLGLYFGIRHYVAEARYIPSESMIPGLQVQDRLLVEKVSLRSR
SPRRGEIVVFNTPYSFNSALNLKSGQSALPCFVVNLPFMNWIGLTNPSCDAWIKRVVAVGGDQVSINPRGEVSVNGQRLK
EPYVTQYCPVNNRGMGPCNSLIATVPSDHVLVLGDNRSNSTDGRIWGFLPEKEILGRALWRFWPFDRFGSLIP

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 26168; Mature: 26037

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAQQQDHPTNDKASAPQGASTSKPHPFWDFWGPVFFTLGLYFGIRHYVAEARYIPSES
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
MIPGLQVQDRLLVEKVSLRSRSPRRGEIVVFNTPYSFNSALNLKSGQSALPCFVVNLPFM
CCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCEEEEECCCH
NWIGLTNPSCDAWIKRVVAVGGDQVSINPRGEVSVNGQRLKEPYVTQYCPVNNRGMGPCN
HHCCCCCCCHHHHHHHHHHCCCCEEEECCCCCEEECHHHHCCCCCCEECCCCCCCCCHHH
SLIATVPSDHVLVLGDNRSNSTDGRIWGFLPEKEILGRALWRFWPFDRFGSLIP
HHHEECCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHCCHHHHCCCCC
>Mature Secondary Structure 
SDAQQQDHPTNDKASAPQGASTSKPHPFWDFWGPVFFTLGLYFGIRHYVAEARYIPSES
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
MIPGLQVQDRLLVEKVSLRSRSPRRGEIVVFNTPYSFNSALNLKSGQSALPCFVVNLPFM
CCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCEEEEECCCH
NWIGLTNPSCDAWIKRVVAVGGDQVSINPRGEVSVNGQRLKEPYVTQYCPVNNRGMGPCN
HHCCCCCCCHHHHHHHHHHCCCCEEEECCCCCEEECHHHHCCCCCCEECCCCCCCCCHHH
SLIATVPSDHVLVLGDNRSNSTDGRIWGFLPEKEILGRALWRFWPFDRFGSLIP
HHHEECCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]