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The map label for this gene is gpmI

Identifier: 124022218

GI number: 124022218

Start: 499501

End: 501123

Strand: Reverse

Name: gpmI

Synonym: P9303_05081

Alternate gene names: 124022218

Gene position: 501123-499501 (Counterclockwise)

Preceding gene: 124022220

Following gene: 124022217

Centisome position: 18.68

GC content: 56.99

Gene sequence:

>1623_bases
ATGTCCAGCAGCAGTTCCGGAAATTCAAGGCATTTCGGCCGGGTTGCACCTGTAGTGCTGGCGATCCTTGATGGCTGGGG
ACATCGTGAGGAACTTGAGCACAACTCCATCCGTAGTGCTGAGACTCCAATCATGGATGCCCTATGGCATGCCTACCCCC
ACACCCTGATCGAAGCCAGTGGTGCCGCTGTCGGGCTGCCAGACAACCAGATGGGCAACTCTGAGGTCGGTCATCTCACC
ATCGGTGCTGGCCGGGTGATCCGTCAGGAACTCGTTCGCATTAGTGAAACCGTACAAACCGGAAGGCTGGGGCAAACTCC
TGCCCTGATTGCCTTAGCCGAACGGTTGCGCAAGTCTGACGGCACACTTCACCTGTTGGGACTCTGCTCCGATGGCGGTG
TCCATAGCCATATCAACCATCTCTGCGGTCTTTTGCACTGGGCTGCCGCCGCTGGGCTCAACAAAGTGGCATTGCATCTC
ATCACCGATGGACGAGACACCCCGACTCAAAGCGCGAGCAACTACCTACACCAAATCGAAGACGCCATCAACGCCAGTGG
AGTAGGTGAGTTGGCCAGCCTCTGCGGCCGCTATTGGGCCATGGACCGTGACCACCGCTGGGAGCGCACGATTAGGGCCT
ATGAGGTACTCACCGACCCAAATCAATCGATCAGCAGAGTCACTGCCGAAGACGTTCTCAGCGCAAGTTATGCCAACGGC
ACCACCGACGAATTCCTAGAACCCACACGTCTTAGCAATAACTACTTCAAAGACGGGGATGGCCTCGTGATGTTCAACTT
CCGTCCTGACCGCGCCAGGCAATTGGTGCAATCCCTCACTCTTCCAGACTTCGATGGTTTCCCTCGAGCCAATCAGCCCA
GCCTCGATGTCGTTACCTTCACCCAGTACGAACACGATCTCCCTGTAGCAGTTGCCTTCCCAGCCGAATCACTCGACGAT
CTGCTCGGTCAGGTGGTCTCTGAACACGGCCTACGCCAATACCGCACTGCCGAAACAGAGAAGTATCCCCACGTCACATA
TTTCATGAATGGTGGCATCGAACAGCCACTAGCAGGCGAGGAGCGTCATCTTGTGCCATCCCCCCGCGTGGCCACCTACG
ACCTGGCTCCAGCGATGTCCGCAGACACGCTGACCGAGAGTTGTGTGAAAGCGATTGAGAGTGGCGTGTATTCACTGGTC
ATCATCAACTACGCCAATCCAGATATGGTCGGGCACACCGGTGTGATGGGAGCCGCTCAGGAAGCCATCAGCACCGTGGA
CCGCTGCATCGGCCGATTGCTGGATTCGACCGGACGAATGGGCGGCACTCTGTTGATCACGGCAGACCATGGCAATGCCG
AACTGATGCAAGGTTCAGATGGTCAGGCTTGGACGGCTCACACCACGAACCCCGTGCCTGTGATCTTGGTAGAAGGAGAG
AAACGCAAGCTGTCTGGCTACGGCAATGACATCCAGCTGCGTGCAGGCGGTGGCCTGGCTGACATCGCACCCACGCTGCT
GCAACTGCTGGATTTACCCAAGCCCGATGCCATGTCAGGCTTAACGTTGATTCAAGCCATTGAGTCACCAACACCCTCTG
CAAGACTCCCTCAACCCGTTTGA

Upstream 100 bases:

>100_bases
GTAAAAGCTGACGGAAGTCAGCACAAATGCAGACCAAGACCAAAGGAGGAAGTAACTTCAATCCGGAGAAGTCCTTAATA
AGCAATAGCCGAGTGTGAAC

Downstream 100 bases:

>100_bases
GGCGAACGATCGCGAGCAGAGGTCAGAGCATGATCAACACATCCCTAGACTGAGGCCATGATTACCTCTGTTCTCTCCTG
GGTCTGGGTCGCTTCTGGCG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MSSSSSGNSRHFGRVAPVVLAILDGWGHREELEHNSIRSAETPIMDALWHAYPHTLIEASGAAVGLPDNQMGNSEVGHLT
IGAGRVIRQELVRISETVQTGRLGQTPALIALAERLRKSDGTLHLLGLCSDGGVHSHINHLCGLLHWAAAAGLNKVALHL
ITDGRDTPTQSASNYLHQIEDAINASGVGELASLCGRYWAMDRDHRWERTIRAYEVLTDPNQSISRVTAEDVLSASYANG
TTDEFLEPTRLSNNYFKDGDGLVMFNFRPDRARQLVQSLTLPDFDGFPRANQPSLDVVTFTQYEHDLPVAVAFPAESLDD
LLGQVVSEHGLRQYRTAETEKYPHVTYFMNGGIEQPLAGEERHLVPSPRVATYDLAPAMSADTLTESCVKAIESGVYSLV
IINYANPDMVGHTGVMGAAQEAISTVDRCIGRLLDSTGRMGGTLLITADHGNAELMQGSDGQAWTAHTTNPVPVILVEGE
KRKLSGYGNDIQLRAGGGLADIAPTLLQLLDLPKPDAMSGLTLIQAIESPTPSARLPQPV

Sequences:

>Translated_540_residues
MSSSSSGNSRHFGRVAPVVLAILDGWGHREELEHNSIRSAETPIMDALWHAYPHTLIEASGAAVGLPDNQMGNSEVGHLT
IGAGRVIRQELVRISETVQTGRLGQTPALIALAERLRKSDGTLHLLGLCSDGGVHSHINHLCGLLHWAAAAGLNKVALHL
ITDGRDTPTQSASNYLHQIEDAINASGVGELASLCGRYWAMDRDHRWERTIRAYEVLTDPNQSISRVTAEDVLSASYANG
TTDEFLEPTRLSNNYFKDGDGLVMFNFRPDRARQLVQSLTLPDFDGFPRANQPSLDVVTFTQYEHDLPVAVAFPAESLDD
LLGQVVSEHGLRQYRTAETEKYPHVTYFMNGGIEQPLAGEERHLVPSPRVATYDLAPAMSADTLTESCVKAIESGVYSLV
IINYANPDMVGHTGVMGAAQEAISTVDRCIGRLLDSTGRMGGTLLITADHGNAELMQGSDGQAWTAHTTNPVPVILVEGE
KRKLSGYGNDIQLRAGGGLADIAPTLLQLLDLPKPDAMSGLTLIQAIESPTPSARLPQPV
>Mature_539_residues
SSSSSGNSRHFGRVAPVVLAILDGWGHREELEHNSIRSAETPIMDALWHAYPHTLIEASGAAVGLPDNQMGNSEVGHLTI
GAGRVIRQELVRISETVQTGRLGQTPALIALAERLRKSDGTLHLLGLCSDGGVHSHINHLCGLLHWAAAAGLNKVALHLI
TDGRDTPTQSASNYLHQIEDAINASGVGELASLCGRYWAMDRDHRWERTIRAYEVLTDPNQSISRVTAEDVLSASYANGT
TDEFLEPTRLSNNYFKDGDGLVMFNFRPDRARQLVQSLTLPDFDGFPRANQPSLDVVTFTQYEHDLPVAVAFPAESLDDL
LGQVVSEHGLRQYRTAETEKYPHVTYFMNGGIEQPLAGEERHLVPSPRVATYDLAPAMSADTLTESCVKAIESGVYSLVI
INYANPDMVGHTGVMGAAQEAISTVDRCIGRLLDSTGRMGGTLLITADHGNAELMQGSDGQAWTAHTTNPVPVILVEGEK
RKLSGYGNDIQLRAGGGLADIAPTLLQLLDLPKPDAMSGLTLIQAIESPTPSARLPQPV

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=514, Percent_Identity=46.3035019455253, Blast_Score=471, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI17507741, Length=516, Percent_Identity=41.2790697674419, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI32564249, Length=520, Percent_Identity=41.1538461538462, Blast_Score=392, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_PROM3 (A2C700)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016525.1
- ProteinModelPortal:   A2C700
- SMR:   A2C700
- STRING:   A2C700
- GeneID:   4778931
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_05081
- eggNOG:   COG0696
- HOGENOM:   HBG613255
- OMA:   DHGNAEL
- ProtClustDB:   PRK05434
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 58317; Mature: 58186

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: ACT_SITE 74-74

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSSSGNSRHFGRVAPVVLAILDGWGHREELEHNSIRSAETPIMDALWHAYPHTLIEAS
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCC
GAAVGLPDNQMGNSEVGHLTIGAGRVIRQELVRISETVQTGRLGQTPALIALAERLRKSD
CCEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
GTLHLLGLCSDGGVHSHINHLCGLLHWAAAAGLNKVALHLITDGRDTPTQSASNYLHQIE
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
DAINASGVGELASLCGRYWAMDRDHRWERTIRAYEVLTDPNQSISRVTAEDVLSASYANG
HHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
TTDEFLEPTRLSNNYFKDGDGLVMFNFRPDRARQLVQSLTLPDFDGFPRANQPSLDVVTF
CHHHHCCCHHCCCCCEECCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEE
TQYEHDLPVAVAFPAESLDDLLGQVVSEHGLRQYRTAETEKYPHVTYFMNGGIEQPLAGE
ECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
ERHLVPSPRVATYDLAPAMSADTLTESCVKAIESGVYSLVIINYANPDMVGHTGVMGAAQ
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHH
EAISTVDRCIGRLLDSTGRMGGTLLITADHGNAELMQGSDGQAWTAHTTNPVPVILVEGE
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCEEEEECCCCEEEEEECCC
KRKLSGYGNDIQLRAGGGLADIAPTLLQLLDLPKPDAMSGLTLIQAIESPTPSARLPQPV
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SSSSSGNSRHFGRVAPVVLAILDGWGHREELEHNSIRSAETPIMDALWHAYPHTLIEAS
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCC
GAAVGLPDNQMGNSEVGHLTIGAGRVIRQELVRISETVQTGRLGQTPALIALAERLRKSD
CCEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
GTLHLLGLCSDGGVHSHINHLCGLLHWAAAAGLNKVALHLITDGRDTPTQSASNYLHQIE
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
DAINASGVGELASLCGRYWAMDRDHRWERTIRAYEVLTDPNQSISRVTAEDVLSASYANG
HHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
TTDEFLEPTRLSNNYFKDGDGLVMFNFRPDRARQLVQSLTLPDFDGFPRANQPSLDVVTF
CHHHHCCCHHCCCCCEECCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEE
TQYEHDLPVAVAFPAESLDDLLGQVVSEHGLRQYRTAETEKYPHVTYFMNGGIEQPLAGE
ECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
ERHLVPSPRVATYDLAPAMSADTLTESCVKAIESGVYSLVIINYANPDMVGHTGVMGAAQ
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHH
EAISTVDRCIGRLLDSTGRMGGTLLITADHGNAELMQGSDGQAWTAHTTNPVPVILVEGE
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCEEEEECCCCEEEEEECCC
KRKLSGYGNDIQLRAGGGLADIAPTLLQLLDLPKPDAMSGLTLIQAIESPTPSARLPQPV
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA