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The map label for this gene is 124022207

Identifier: 124022207

GI number: 124022207

Start: 490932

End: 491675

Strand: Reverse

Name: 124022207

Synonym: P9303_04971

Alternate gene names: NA

Gene position: 491675-490932 (Counterclockwise)

Preceding gene: 124022210

Following gene: 124022204

Centisome position: 18.33

GC content: 56.72

Gene sequence:

>744_bases
GTGATCCGCGATGTAGCAGCCAGCTACCGCCGCGCCATCCAGGAAACAGTGCACCATTACAGCGGCTGGCGTCCCAGCGT
CGCTGAGATCGACGCACTCAAAACAGAAGGCATCTGGAATAACGACTGGGACGCCAGCCTGGAGCTCCTGGGTCGTCATC
AGAAAAGCCGTAACCAAGCCCTAGAGCTACCGAGCCGCGAGCAGCTCATAGAGGTGTTTAGTCGTTTTTATTTTGGCGGT
GATCCCAATGGCGACCCCAGCAATTGGCAGGGCTTTATCCGCAATGAGCCACTGCTGGTCAATCAAAGATTCTTTGAGGA
GCTGAGTTCGCTCGGCTTCGCCTGGGGGTTTGTTAGCGGTGCTGAGCCTCCTTCTGCCCGCTTTGTATTGGAACAACGCT
TGGGGCTCAAGCATCCAGCCTTGATCGCCATGGGCGAAGCACCTGACAAACCAGATCCCACTGGCCTGCTTCAACTAGCC
AGCCAACTTGCTGGTAGGAGATTGGGTCAAGGCGTTCCAACAGTCGCCTACCTAGGCGACACGGTGGCCGATGTGCGCAC
AGTGATCAATGCCCGCCAGCAACAACCCGAGCAGCAATGGATGAGCTTGGCCGTAGCGCCACCCCATTTACATGGGATCG
AGCAACAAGAAGCACGCAACGCCTATGAAGATCGACTGAAGCAGGCCGGCGCCGATCACATTCTGAGCTGCACAACCGAT
GCGATCGAGACCCTCAAAAACTAG

Upstream 100 bases:

>100_bases
TCTGCGCTCAAGGAATCTGAACAAACAACTAACCTAACAGTCGCTCAACACTCTCTATCCACTGAACCTGCAAGGCCTGC
TGCTGTTTGACATCGACGGC

Downstream 100 bases:

>100_bases
TGAAGATCTCGTCTGGCCAGGTTCGGCCATCTCCTTGATCTCGCTTAGAGCTGCTAAGGAACTTGGGTGAAAGCATGGCT
AATGCTTGAGCGCTGATGCC

Product: imidazoleglycerol-phosphate dehydratase

Products: 3-(imidazol-4-yl)-2-oxopropyl phosphate; H2O

Alternate protein names: HAD Superfamily Hydrolase; HAD Family Hydrolase; HAD Superfamily Phosphatase; HAD Superfamily Hydrolase TIGR

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MIRDVAASYRRAIQETVHHYSGWRPSVAEIDALKTEGIWNNDWDASLELLGRHQKSRNQALELPSREQLIEVFSRFYFGG
DPNGDPSNWQGFIRNEPLLVNQRFFEELSSLGFAWGFVSGAEPPSARFVLEQRLGLKHPALIAMGEAPDKPDPTGLLQLA
SQLAGRRLGQGVPTVAYLGDTVADVRTVINARQQQPEQQWMSLAVAPPHLHGIEQQEARNAYEDRLKQAGADHILSCTTD
AIETLKN

Sequences:

>Translated_247_residues
MIRDVAASYRRAIQETVHHYSGWRPSVAEIDALKTEGIWNNDWDASLELLGRHQKSRNQALELPSREQLIEVFSRFYFGG
DPNGDPSNWQGFIRNEPLLVNQRFFEELSSLGFAWGFVSGAEPPSARFVLEQRLGLKHPALIAMGEAPDKPDPTGLLQLA
SQLAGRRLGQGVPTVAYLGDTVADVRTVINARQQQPEQQWMSLAVAPPHLHGIEQQEARNAYEDRLKQAGADHILSCTTD
AIETLKN
>Mature_247_residues
MIRDVAASYRRAIQETVHHYSGWRPSVAEIDALKTEGIWNNDWDASLELLGRHQKSRNQALELPSREQLIEVFSRFYFGG
DPNGDPSNWQGFIRNEPLLVNQRFFEELSSLGFAWGFVSGAEPPSARFVLEQRLGLKHPALIAMGEAPDKPDPTGLLQLA
SQLAGRRLGQGVPTVAYLGDTVADVRTVINARQQQPEQQWMSLAVAPPHLHGIEQQEARNAYEDRLKQAGADHILSCTTD
AIETLKN

Specific function: Unknown

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.19

Molecular weight: Translated: 27590; Mature: 27590

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRDVAASYRRAIQETVHHYSGWRPSVAEIDALKTEGIWNNDWDASLELLGRHQKSRNQA
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LELPSREQLIEVFSRFYFGGDPNGDPSNWQGFIRNEPLLVNQRFFEELSSLGFAWGFVSG
HCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEECHHHHHHHHHHHHHHHHCCC
AEPPSARFVLEQRLGLKHPALIAMGEAPDKPDPTGLLQLASQLAGRRLGQGVPTVAYLGD
CCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TVADVRTVINARQQQPEQQWMSLAVAPPHLHGIEQQEARNAYEDRLKQAGADHILSCTTD
HHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
AIETLKN
HHHHHCC
>Mature Secondary Structure
MIRDVAASYRRAIQETVHHYSGWRPSVAEIDALKTEGIWNNDWDASLELLGRHQKSRNQA
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LELPSREQLIEVFSRFYFGGDPNGDPSNWQGFIRNEPLLVNQRFFEELSSLGFAWGFVSG
HCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEECHHHHHHHHHHHHHHHHCCC
AEPPSARFVLEQRLGLKHPALIAMGEAPDKPDPTGLLQLASQLAGRRLGQGVPTVAYLGD
CCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TVADVRTVINARQQQPEQQWMSLAVAPPHLHGIEQQEARNAYEDRLKQAGADHILSCTTD
HHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
AIETLKN
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate

Specific reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA