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The map label for this gene is rpoC1 [H]

Identifier: 124022147

GI number: 124022147

Start: 440316

End: 442220

Strand: Direct

Name: rpoC1 [H]

Synonym: P9303_04371

Alternate gene names: 124022147

Gene position: 440316-442220 (Clockwise)

Preceding gene: 124022146

Following gene: 124022149

Centisome position: 16.41

GC content: 50.24

Gene sequence:

>1905_bases
ATGACTAACAGCAACCTCCGTACAGAGAACCACTTCGATTACGTCAAGATCACACTTGCTTCACCAGACCGGGTGATGGA
GTGGGGTCAGCGGACACTTCCTAATGGGCAGGTAGTGGGTGAAGTGACGAAGCCGGAGACGATCAATTACCGCACCCTTA
AGCCTGAGATGGACGGGCTCTTTTGCGAGAAGATCTTCGGCCCTTCAAAGGATTGGGAGTGTCATTGCGGGAAATATAAG
CGTGTTCGACACCGTGGCATTGTCTGTGAGCGCTGTGGCGTGGAGGTCACTGAAAGTCGGGTCCGGCGTCATCGCATGGG
CTTCATCAAGTTGGCTGCTCCTGTCTCCCACGTTTGGTATTTGAAAGGGATACCTAGTTATGTGGCGATCTTGTTAGATA
TGCCTCTACGCGATGTTGAACAGATTGTTTACTTCAACTGTTATGTCGTGCTCGATCCTGGCGATCATAAGGAACTCAAG
TATAAGCAGTTACTGACTGAGGATGAGTGGCTAGAGATCGAAGATGAGATCTATGCGGAAGATTCCACGATTGAGAATGA
GCCGATAGTTGGCATCGGGGCTGAAGCCCTAAAGCAATTGCTAGAAGATTTGAATTTGGCTGAGGTTGCTGAACAGTTGA
GAGAGGATATTTCCTCTAGCAAGGGTCAGAAACGGGCCAAGTTGATTAAGCGTTTGAGAGTGATTGATAACTTTATTGCC
ACTAACGCAAGGCCTGAGTGGATGGTGCTGGATGCAATTCCAGTTATTCCTCCAGATTTGCGCCCCATGGTGCAATTAGA
TGGTGGACGTTTCGCTACATCCGATCTAAATGATCTCTACCGTCGGGTGATTAACCGCAACAACCGTCTTGCGCGGCTTC
AGGAAATCTTGGCTCCTGAGATTATCGTTCGCAATGAGAAGCGGATGCTCCAAGAGGCAGTTGATGCTCTGATCGATAAT
GGTCGTCGTGGTCGAACTGTTGTTGGTGCTAATAATCGCCCGTTGAAGTCACTTAGTGACATCATTGAGGGCAAACAGGG
TCGCTTCCGCCAGAACTTGTTAGGTAAGCGGGTCGACTATTCTGGTCGTTCCGTGATCGTGGTGGGCCCCAAGCTGAAGA
TGCATCAGTGCGGCTTGCCTAAAGAGATGGCAATCGAGCTATTCCAGCCTTTTGTGATCCATCGCCTGATTCGTCAAAAC
ATTGTCAACAACATCAAAGCCGCTAAGAAGTTGATCCAGCGAGCTGATGATGAGGTCATGCAGGTGCTGCAGGAGGTCAT
TGAGGGGCACCCGATCCTTTTAAACCGCGCTCCAACTCTGCACCGTCTGGGTATACAGGCTTTTGAACCGAAGCTGGTTG
CTGGCCGTGCCATTCAGCTTCACCCGTTGGTTTGCCCTGCCTTTAACGCCGACTTTGATGGCGACCAAATGGCTGTTCAT
GTGCCTTTGGCGATTGAGGCTCAGACGGAAGCGCGAATGTTGATGTTGGCCAGCAACAACATCCTTTCACCTGCCACTGG
CGATCCGATCATCACGCCTTCCCAGGACATGGTGCTTGGCTCCTATTACCTAACGGCGATTAAGCCTGGAGCTTCTGTTC
CTGAGTTTGGCGATCAATCCAGAACCTATGCTGGTTTAGAGGACGTCATCCATGCGTTTGAAGATAAAAGACTCCTACTG
CATGACTGGGTTTGGGTTCGCTTCAACGGTGAGGTAGAGGATGAAGATGAAATTGACAAACCTCTCAAGGCTGAATCACT
TAGTGATGGCACTCGCATTGAGCAGTGGACTTATCGCCGAGATCGTTTCGACGAAGACGGAGCATTGATCAGTCGCTACA
TCCTTACAACAGTGGGACGCGTGGTGATGAATTACACAATTATCGATGCGGTGGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
AGTCGACCCACTTACGAATCCCTTGGAGTAGCGGATTACGACGAAGATTAACGGCCTTATCTAACTGCTTTTCGTTTCCC
AAACTGTTTGCGATTCGTTC

Downstream 100 bases:

>100_bases
GTCACTCCAATACCAGCTTTCTTCCCTGACCTGATTCGCGTGTAGCCATGACCTCAACCTCCCCGAAATCCCGCAAGCCT
TCGACCAAGACCACCAAGTC

Product: DNA-directed RNA polymerase subunit gamma

Products: NA

Alternate protein names: RNAP subunit gamma; RNA polymerase subunit gamma; Transcriptase subunit gamma [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MTNSNLRTENHFDYVKITLASPDRVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYK
RVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDPGDHKELK
YKQLLTEDEWLEIEDEIYAEDSTIENEPIVGIGAEALKQLLEDLNLAEVAEQLREDISSSKGQKRAKLIKRLRVIDNFIA
TNARPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDN
GRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQN
IVNNIKAAKKLIQRADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVAGRAIQLHPLVCPAFNADFDGDQMAVH
VPLAIEAQTEARMLMLASNNILSPATGDPIITPSQDMVLGSYYLTAIKPGASVPEFGDQSRTYAGLEDVIHAFEDKRLLL
HDWVWVRFNGEVEDEDEIDKPLKAESLSDGTRIEQWTYRRDRFDEDGALISRYILTTVGRVVMNYTIIDAVAAA

Sequences:

>Translated_634_residues
MTNSNLRTENHFDYVKITLASPDRVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYK
RVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDPGDHKELK
YKQLLTEDEWLEIEDEIYAEDSTIENEPIVGIGAEALKQLLEDLNLAEVAEQLREDISSSKGQKRAKLIKRLRVIDNFIA
TNARPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDN
GRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQN
IVNNIKAAKKLIQRADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVAGRAIQLHPLVCPAFNADFDGDQMAVH
VPLAIEAQTEARMLMLASNNILSPATGDPIITPSQDMVLGSYYLTAIKPGASVPEFGDQSRTYAGLEDVIHAFEDKRLLL
HDWVWVRFNGEVEDEDEIDKPLKAESLSDGTRIEQWTYRRDRFDEDGALISRYILTTVGRVVMNYTIIDAVAAA
>Mature_633_residues
TNSNLRTENHFDYVKITLASPDRVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYKR
VRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDPGDHKELKY
KQLLTEDEWLEIEDEIYAEDSTIENEPIVGIGAEALKQLLEDLNLAEVAEQLREDISSSKGQKRAKLIKRLRVIDNFIAT
NARPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNG
RRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNI
VNNIKAAKKLIQRADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVAGRAIQLHPLVCPAFNADFDGDQMAVHV
PLAIEAQTEARMLMLASNNILSPATGDPIITPSQDMVLGSYYLTAIKPGASVPEFGDQSRTYAGLEDVIHAFEDKRLLLH
DWVWVRFNGEVEDEDEIDKPLKAESLSDGTRIEQWTYRRDRFDEDGALISRYILTTVGRVVMNYTIIDAVAAA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=312, Percent_Identity=31.0897435897436, Blast_Score=153, Evalue=6e-37,
Organism=Homo sapiens, GI39725938, Length=321, Percent_Identity=28.6604361370716, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI103471997, Length=224, Percent_Identity=30.8035714285714, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI2367335, Length=523, Percent_Identity=61.5678776290631, Blast_Score=693, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=305, Percent_Identity=31.4754098360656, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25145495, Length=308, Percent_Identity=31.1688311688312, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71998295, Length=336, Percent_Identity=24.4047619047619, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320061, Length=490, Percent_Identity=27.7551020408163, Blast_Score=146, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6324690, Length=227, Percent_Identity=38.3259911894273, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI17530899, Length=309, Percent_Identity=29.7734627831715, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360912, Length=503, Percent_Identity=26.8389662027833, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI17647875, Length=337, Percent_Identity=28.1899109792285, Blast_Score=108, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR012755 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 72088; Mature: 71957

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSNLRTENHFDYVKITLASPDRVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGL
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCH
FCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWY
HHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEEECHHHHHHH
LKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDPGDHKELKYKQLLTEDEWLEIEDEIYAE
HHCHHHHHHHHHCCCHHHHHHEEEEEEEEEECCCCCCHHHHHHHCCCCCCEEECHHHCCC
DSTIENEPIVGIGAEALKQLLEDLNLAEVAEQLREDISSSKGQKRAKLIKRLRVIDNFIA
CCCCCCCCCEEECHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TNARPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPE
CCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCH
IIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDY
HEECCHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQRADDEVM
CCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVAGRAIQLHPLVCPAFNADFDGDQMAVH
HHHHHHHCCCCEEEECCCCHHHHCHHHCCCHHHCCCEEEEECEECCCCCCCCCCCCEEEE
VPLAIEAQTEARMLMLASNNILSPATGDPIITPSQDMVLGSYYLTAIKPGASVPEFGDQS
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEHHEEEEEECCCCCCCCCCCCC
RTYAGLEDVIHAFEDKRLLLHDWVWVRFNGEVEDEDEIDKPLKAESLSDGTRIEQWTYRR
CHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHH
DRFDEDGALISRYILTTVGRVVMNYTIIDAVAAA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNSNLRTENHFDYVKITLASPDRVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGL
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCH
FCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWY
HHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEEECHHHHHHH
LKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDPGDHKELKYKQLLTEDEWLEIEDEIYAE
HHCHHHHHHHHHCCCHHHHHHEEEEEEEEEECCCCCCHHHHHHHCCCCCCEEECHHHCCC
DSTIENEPIVGIGAEALKQLLEDLNLAEVAEQLREDISSSKGQKRAKLIKRLRVIDNFIA
CCCCCCCCCEEECHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TNARPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPE
CCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCH
IIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDY
HEECCHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQRADDEVM
CCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVAGRAIQLHPLVCPAFNADFDGDQMAVH
HHHHHHHCCCCEEEECCCCHHHHCHHHCCCHHHCCCEEEEECEECCCCCCCCCCCCEEEE
VPLAIEAQTEARMLMLASNNILSPATGDPIITPSQDMVLGSYYLTAIKPGASVPEFGDQS
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEHHEEEEEECCCCCCCCCCCCC
RTYAGLEDVIHAFEDKRLLLHDWVWVRFNGEVEDEDEIDKPLKAESLSDGTRIEQWTYRR
CHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHH
DRFDEDGALISRYILTTVGRVVMNYTIIDAVAAA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA