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The map label for this gene is tatD [C]

Identifier: 124022145

GI number: 124022145

Start: 435856

End: 436689

Strand: Direct

Name: tatD [C]

Synonym: P9303_04351

Alternate gene names: 124022145

Gene position: 435856-436689 (Clockwise)

Preceding gene: 124022144

Following gene: 124022146

Centisome position: 16.25

GC content: 55.4

Gene sequence:

>834_bases
ATGAGGAAAGGCCTGCACAATGGGGCCAAAGATGCGTTTTCGGTTCTGGTGTCGTCTCCGATTCTTATCGATAGTCATTG
TCACATCGTCTTTCGCAATTTCGATGATGATCTCGATGAGGTAGCTGCACGCTGGCGACAGGCCGGCGTAGCGAGTCTGC
TGCATGCGTGCGTGGAACCCGCAGAGATTCCTGCGATTCGTGCTTTGGCGGATCGTTTCCCTGAACTGCGCTATTCAGTG
GGGGTTCATCCCCTCGACACGCAGCACTGGAATCCTCAGACGCAGTCGCTTTTGCGAGATGCAGCTCTTGAAGATCCAAG
GGTGGTGGCTATTGGTGAACTGGGGCTTGATCTTTACCGGGATTCAAACCTTGAACAGCAGTTGGCTGTGCTGAGACCGC
AGTTGGACTTGGCCACGGAGTTAGATCTACCCGTGATCATTCATTGTCGTGATGCATTTGATCCCATGACGTTGGAGTTG
CGTCAGCGCCAGAAGGAGGGTCGTTGCCCTAGGGGGGTGATGCATTGCTGGGGCGGCACAACAGAGGATATGGAGGTCTG
CTTGGATCTTGGTCTTTACATCAGTTTCAGTGGCACAGTCACCTTCCCGAAGGCTGAGGCCATTCACGCCTGCGCGCGCG
AAGTCCCGCAGAATCGTTTTCTAGTCGAGACGGATTGCCCGTTTCTGGCCCCAGTGCCTCGTAGGGGTAAGCGCAATGAG
CCTGCCTACGTCGAGGCGGTGGCTTCTCGGGTGGCTGAGCTTCGAGGGGAGTCTTTGGCCTTAGTCGCAAGCAGTAGCAC
GGCTAATGCAAGACGATTGTTCTCTTTGCCCTGA

Upstream 100 bases:

>100_bases
CTCGTCTTAGTGCAGCGGTGAAGCAGGCGATTGAACCGGCGCCAAGCACTTAGGACTGATTTGGCATGGTCCATTGTGAA
AGGGCTTGTTCTTTCCCTTG

Downstream 100 bases:

>100_bases
TCTCAAGACATTGGACAGGTGTTTGGCGGCCTACAAGTGTAAAATTGTTGACTGGTCTGGCCATGATGCAGTTTTTCTGC
TTCCCTGCCGCCCGAAGCGC

Product: deoxyribonuclease, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MRKGLHNGAKDAFSVLVSSPILIDSHCHIVFRNFDDDLDEVAARWRQAGVASLLHACVEPAEIPAIRALADRFPELRYSV
GVHPLDTQHWNPQTQSLLRDAALEDPRVVAIGELGLDLYRDSNLEQQLAVLRPQLDLATELDLPVIIHCRDAFDPMTLEL
RQRQKEGRCPRGVMHCWGGTTEDMEVCLDLGLYISFSGTVTFPKAEAIHACAREVPQNRFLVETDCPFLAPVPRRGKRNE
PAYVEAVASRVAELRGESLALVASSSTANARRLFSLP

Sequences:

>Translated_277_residues
MRKGLHNGAKDAFSVLVSSPILIDSHCHIVFRNFDDDLDEVAARWRQAGVASLLHACVEPAEIPAIRALADRFPELRYSV
GVHPLDTQHWNPQTQSLLRDAALEDPRVVAIGELGLDLYRDSNLEQQLAVLRPQLDLATELDLPVIIHCRDAFDPMTLEL
RQRQKEGRCPRGVMHCWGGTTEDMEVCLDLGLYISFSGTVTFPKAEAIHACAREVPQNRFLVETDCPFLAPVPRRGKRNE
PAYVEAVASRVAELRGESLALVASSSTANARRLFSLP
>Mature_277_residues
MRKGLHNGAKDAFSVLVSSPILIDSHCHIVFRNFDDDLDEVAARWRQAGVASLLHACVEPAEIPAIRALADRFPELRYSV
GVHPLDTQHWNPQTQSLLRDAALEDPRVVAIGELGLDLYRDSNLEQQLAVLRPQLDLATELDLPVIIHCRDAFDPMTLEL
RQRQKEGRCPRGVMHCWGGTTEDMEVCLDLGLYISFSGTVTFPKAEAIHACAREVPQNRFLVETDCPFLAPVPRRGKRNE
PAYVEAVASRVAELRGESLALVASSSTANARRLFSLP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=266, Percent_Identity=29.3233082706767, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI110349734, Length=266, Percent_Identity=29.3233082706767, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=29.1970802919708, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI14042943, Length=268, Percent_Identity=27.2388059701493, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI226061614, Length=254, Percent_Identity=28.3464566929134, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI225903439, Length=225, Percent_Identity=28.4444444444444, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI225903424, Length=275, Percent_Identity=26.9090909090909, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI226061595, Length=231, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1787342, Length=261, Percent_Identity=39.463601532567, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI48994985, Length=261, Percent_Identity=33.3333333333333, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=32.046332046332, Blast_Score=128, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17559024, Length=283, Percent_Identity=28.9752650176678, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71980746, Length=269, Percent_Identity=26.3940520446097, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17565396, Length=301, Percent_Identity=24.9169435215947, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648690, Length=289, Percent_Identity=31.1418685121107, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI221330018, Length=217, Percent_Identity=30.8755760368664, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24586117, Length=217, Percent_Identity=30.8755760368664, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30794; Mature: 30794

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKGLHNGAKDAFSVLVSSPILIDSHCHIVFRNFDDDLDEVAARWRQAGVASLLHACVEP
CCCCCCCCHHHHHHHHHCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
AEIPAIRALADRFPELRYSVGVHPLDTQHWNPQTQSLLRDAALEDPRVVAIGELGLDLYR
HHCHHHHHHHHHCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHC
DSNLEQQLAVLRPQLDLATELDLPVIIHCRDAFDPMTLELRQRQKEGRCPRGVMHCWGGT
CCCHHHHHHHHCCCCCHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHCCCC
TEDMEVCLDLGLYISFSGTVTFPKAEAIHACAREVPQNRFLVETDCPFLAPVPRRGKRNE
CHHHHHHHHHCEEEEECCEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCC
PAYVEAVASRVAELRGESLALVASSSTANARRLFSLP
CHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEECCC
>Mature Secondary Structure
MRKGLHNGAKDAFSVLVSSPILIDSHCHIVFRNFDDDLDEVAARWRQAGVASLLHACVEP
CCCCCCCCHHHHHHHHHCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
AEIPAIRALADRFPELRYSVGVHPLDTQHWNPQTQSLLRDAALEDPRVVAIGELGLDLYR
HHCHHHHHHHHHCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHC
DSNLEQQLAVLRPQLDLATELDLPVIIHCRDAFDPMTLELRQRQKEGRCPRGVMHCWGGT
CCCHHHHHHHHCCCCCHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHCCCC
TEDMEVCLDLGLYISFSGTVTFPKAEAIHACAREVPQNRFLVETDCPFLAPVPRRGKRNE
CHHHHHHHHHCEEEEECCEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCC
PAYVEAVASRVAELRGESLALVASSSTANARRLFSLP
CHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]