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The map label for this gene is ynaI [H]

Identifier: 124022127

GI number: 124022127

Start: 417232

End: 418344

Strand: Direct

Name: ynaI [H]

Synonym: P9303_04171

Alternate gene names: 124022127

Gene position: 417232-418344 (Clockwise)

Preceding gene: 124022121

Following gene: 124022131

Centisome position: 15.55

GC content: 47.35

Gene sequence:

>1113_bases
ATGCCTCTGATGACGCCCCTTCCCTTCAATCTTCAGGTGCCGATTGCCGGCCTTGTTTTGGCCATTGTCAGCTGGTTGTT
GCTAGACACTCTTGGCAGGCGGTTCCGCTCAGGTTCGTTGCGGCGTGGATTGCTGCTCAGTAGCAGGCAAAGCATTTCCC
TGAGTTGCGCACTTGTAGGAGTGATTTGTTGGCTGTTGGATTTGTTGGATCCGTCATTGATTCAATTCCCGCGTGATGGC
GTTAAGGCGTTTGGAATTCTTGTGGTCATAGGTCTTTCATGGACGCTGCTGTCTTGGAAGAAGGAGCTCAAGCAAAACCA
AGAGAGGTATGCCACTCAGATGCTGCGGGGCTTTGGGGAAAAAGACAGGCGGTTCCTGTTCGATGTTGTTCAGAAGAGCA
TCGGTATTGCTGCCATGGTCATTTTGTGGCTGGAGGTGATGCATCTGATGGGTATTTCACCGGCCGTGCTGGTTACCGCC
GGTGGGGTTGGCGCCGTTGCATTGGGTTTCGGGGCCAAGGGGATTGTTTCGAATTCCTTAAGCGGCCTTAGTCTTTACAT
TAACCGTCCCTTTGTGGTAAGTGATTTTATTGATATTCCTTCCGAAAATCTTTCTGGAAATGTAGAACATATCGGTTGGT
TTTATACCAAGTTGCGTTCCTCTGATCGTCAACCAGTGTACATACCAAATAACATCTTTACAAGTAAGCCGGTTGTCAAT
ATTGCTGATATAGACAACCGTAGGATTTGGATTGAATTTGGCGTTAATTATGGCGATCGTAGAAGGATTGAGTCGATTGT
GAGTGATCTTCAGCAGGTTTTAGTTAATCATCCAGATGTAGATCAGAGCAAGAAAATGGCCGTGAATTTCACCGGCTATG
GCGATTCGAGTCTGAATCTGCGTTTGGTCTGTTATTCCTCTAGTGGAAATTTAAGCGATGCTTGGGCCTTGCAGCAGAGG
CTGCTTCTCAAGATTGGTGATGTGGTTGAAGCGCATGGTGCAGGAATGCCATTCCCCACACGCACTTTGATTCATTCAGG
ATTGAATCAAATGCCGCAAACGATGAATCCTCTGATAGGAATCAATCAAGAATCGGGTGAAGGTGCAATTTGA

Upstream 100 bases:

>100_bases
AGAATTCGCTAGTCAGCGCCCGCCGGCCGTTGGGAAGCGATTGGCTTCGCAGAACTAAAGCTTCGTAGACAATTCAAATC
CGTGCGGATGCATCTTGCTT

Downstream 100 bases:

>100_bases
CCCTCCCCGATTCTCTTGTCAATTCCTAATGTTTAGAATCGATTACCGGCAGCCCTGAACAGAAATTCTGTAACTGAATC
CTGTGGATCCTGGATCCTTT

Product: small mechanosensitive ion channel, MscS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MPLMTPLPFNLQVPIAGLVLAIVSWLLLDTLGRRFRSGSLRRGLLLSSRQSISLSCALVGVICWLLDLLDPSLIQFPRDG
VKAFGILVVIGLSWTLLSWKKELKQNQERYATQMLRGFGEKDRRFLFDVVQKSIGIAAMVILWLEVMHLMGISPAVLVTA
GGVGAVALGFGAKGIVSNSLSGLSLYINRPFVVSDFIDIPSENLSGNVEHIGWFYTKLRSSDRQPVYIPNNIFTSKPVVN
IADIDNRRIWIEFGVNYGDRRRIESIVSDLQQVLVNHPDVDQSKKMAVNFTGYGDSSLNLRLVCYSSSGNLSDAWALQQR
LLLKIGDVVEAHGAGMPFPTRTLIHSGLNQMPQTMNPLIGINQESGEGAI

Sequences:

>Translated_370_residues
MPLMTPLPFNLQVPIAGLVLAIVSWLLLDTLGRRFRSGSLRRGLLLSSRQSISLSCALVGVICWLLDLLDPSLIQFPRDG
VKAFGILVVIGLSWTLLSWKKELKQNQERYATQMLRGFGEKDRRFLFDVVQKSIGIAAMVILWLEVMHLMGISPAVLVTA
GGVGAVALGFGAKGIVSNSLSGLSLYINRPFVVSDFIDIPSENLSGNVEHIGWFYTKLRSSDRQPVYIPNNIFTSKPVVN
IADIDNRRIWIEFGVNYGDRRRIESIVSDLQQVLVNHPDVDQSKKMAVNFTGYGDSSLNLRLVCYSSSGNLSDAWALQQR
LLLKIGDVVEAHGAGMPFPTRTLIHSGLNQMPQTMNPLIGINQESGEGAI
>Mature_369_residues
PLMTPLPFNLQVPIAGLVLAIVSWLLLDTLGRRFRSGSLRRGLLLSSRQSISLSCALVGVICWLLDLLDPSLIQFPRDGV
KAFGILVVIGLSWTLLSWKKELKQNQERYATQMLRGFGEKDRRFLFDVVQKSIGIAAMVILWLEVMHLMGISPAVLVTAG
GVGAVALGFGAKGIVSNSLSGLSLYINRPFVVSDFIDIPSENLSGNVEHIGWFYTKLRSSDRQPVYIPNNIFTSKPVVNI
ADIDNRRIWIEFGVNYGDRRRIESIVSDLQQVLVNHPDVDQSKKMAVNFTGYGDSSLNLRLVCYSSSGNLSDAWALQQRL
LLKIGDVVEAHGAGMPFPTRTLIHSGLNQMPQTMNPLIGINQESGEGAI

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1787591, Length=310, Percent_Identity=33.8709677419355, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1786670, Length=157, Percent_Identity=32.484076433121, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789291, Length=195, Percent_Identity=25.1282051282051, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 40804; Mature: 40673

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLMTPLPFNLQVPIAGLVLAIVSWLLLDTLGRRFRSGSLRRGLLLSSRQSISLSCALVG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHH
VICWLLDLLDPSLIQFPRDGVKAFGILVVIGLSWTLLSWKKELKQNQERYATQMLRGFGE
HHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KDRRFLFDVVQKSIGIAAMVILWLEVMHLMGISPAVLVTAGGVGAVALGFGAKGIVSNSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCCHHHHCCC
SGLSLYINRPFVVSDFIDIPSENLSGNVEHIGWFYTKLRSSDRQPVYIPNNIFTSKPVVN
CCEEEEEECCEEEEHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEE
IADIDNRRIWIEFGVNYGDRRRIESIVSDLQQVLVNHPDVDQSKKMAVNFTGYGDSSLNL
EEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEE
RLVCYSSSGNLSDAWALQQRLLLKIGDVVEAHGAGMPFPTRTLIHSGLNQMPQTMNPLIG
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
INQESGEGAI
CCCCCCCCCC
>Mature Secondary Structure 
PLMTPLPFNLQVPIAGLVLAIVSWLLLDTLGRRFRSGSLRRGLLLSSRQSISLSCALVG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHH
VICWLLDLLDPSLIQFPRDGVKAFGILVVIGLSWTLLSWKKELKQNQERYATQMLRGFGE
HHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KDRRFLFDVVQKSIGIAAMVILWLEVMHLMGISPAVLVTAGGVGAVALGFGAKGIVSNSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCCHHHHCCC
SGLSLYINRPFVVSDFIDIPSENLSGNVEHIGWFYTKLRSSDRQPVYIPNNIFTSKPVVN
CCEEEEEECCEEEEHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEE
IADIDNRRIWIEFGVNYGDRRRIESIVSDLQQVLVNHPDVDQSKKMAVNFTGYGDSSLNL
EEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEE
RLVCYSSSGNLSDAWALQQRLLLKIGDVVEAHGAGMPFPTRTLIHSGLNQMPQTMNPLIG
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
INQESGEGAI
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]