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The map label for this gene is aspA

Identifier: 124022112

GI number: 124022112

Start: 403795

End: 404766

Strand: Direct

Name: aspA

Synonym: P9303_04021

Alternate gene names: NA

Gene position: 403795-404766 (Clockwise)

Preceding gene: 124022108

Following gene: 124022114

Centisome position: 15.05

GC content: 54.73

Gene sequence:

>972_bases
ATGGTTGTTCCCTTTGCAGCCATTTTCGGTCAGGCTGAGGATTGCGATCGAATCTTGATGTCTGGCCTTCAGGTGCTTCT
GGTGGCGGGTACTCATGGCAATGAAATCAACGCTCCCTGGCTTCTCGATCAATGGTCTCAGACCCCTGAGCTGATCAACA
CCCATGGTGTTGCTGTGGTGCCGGTGATCGGCAATCCAGAGGCTTTTGCGTTGGGCAGGCGTTATTTGGATTGCGATCTC
AACCGCAGCTTTCGGCTCGACTTGCTCAGATCCCCCAGCATCTTGGATCGAGAGGTTGTTCGTGCCAAGCAGCTGCTTAG
TTTTTTTGGTCCAGAGGGATCAACCCCTTGCCAGATCGTTATTGATTTGCACAGCACCACTTCAGCAATGGGAAGCACTC
TTGTGGTTTATGGCCGACGGCCGGCTGACCTGGCTTTAGCCGCATTGATTCAGGCTCGCTTGGGTTTGCCTATCTATTTG
CATGATGGGGATGATGACCAGCAGGGGTTTTTGGTGGAGCGCTGGCCCTGTGGCTTAGTGATTGAAATCGGTCCTGTTCC
CCAGGGCCTCTTGAAGGCCTGCATCATTGAACAGACACGACTTGCTGTTCAGGCCTGTCTCGAGGCTCTGAGCAGCATTT
CATCTGGATCGCCGACCTACCCAGATCAGTTTGTGGTGCACTCTCATCTGGGCAGTCTGGACCTGCCCCGTGATGGCTTG
GGCCAGCCTGCTGCATGTGTGCATCCATATCTTCAGGGCCGTGATTGGCAGCCTCTGCAGATGGGTGCCCCCTTGTTTCT
CCGGCCAGATGGAGAGGTGTTCAGATTTGAAGGACGGGATTCTCCTATCCCCGTTTTTATCAACGAGGCGGCCTACGTTG
AAAAGCACATCGCCATGAGCCTGACCTGTCGAGAGGTCTGCCCCCTGCCTGAGCAATGGCAAGGGGCCCTGCAGCAGTTA
GTCGACTGTTAA

Upstream 100 bases:

>100_bases
GCTCCCATTGGCATCTGCTGGAGCAAGACCGTTCATTAATTGAATCCATTGCCAGTGCCAGCCCATTCGGGCGGCGGCAA
CGATTGCGGGGGGGATCGAC

Downstream 100 bases:

>100_bases
CGAGGGGGGCCGTTGTAAATGATCTGATTGACAGACCTTCCGTCTGGGGCAATCTGAATGACGGTTTCTGTGGTCGGTTC
ATTGCCATATTCCGACCAGC

Product: aspartoacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MVVPFAAIFGQAEDCDRILMSGLQVLLVAGTHGNEINAPWLLDQWSQTPELINTHGVAVVPVIGNPEAFALGRRYLDCDL
NRSFRLDLLRSPSILDREVVRAKQLLSFFGPEGSTPCQIVIDLHSTTSAMGSTLVVYGRRPADLALAALIQARLGLPIYL
HDGDDDQQGFLVERWPCGLVIEIGPVPQGLLKACIIEQTRLAVQACLEALSSISSGSPTYPDQFVVHSHLGSLDLPRDGL
GQPAACVHPYLQGRDWQPLQMGAPLFLRPDGEVFRFEGRDSPIPVFINEAAYVEKHIAMSLTCREVCPLPEQWQGALQQL
VDC

Sequences:

>Translated_323_residues
MVVPFAAIFGQAEDCDRILMSGLQVLLVAGTHGNEINAPWLLDQWSQTPELINTHGVAVVPVIGNPEAFALGRRYLDCDL
NRSFRLDLLRSPSILDREVVRAKQLLSFFGPEGSTPCQIVIDLHSTTSAMGSTLVVYGRRPADLALAALIQARLGLPIYL
HDGDDDQQGFLVERWPCGLVIEIGPVPQGLLKACIIEQTRLAVQACLEALSSISSGSPTYPDQFVVHSHLGSLDLPRDGL
GQPAACVHPYLQGRDWQPLQMGAPLFLRPDGEVFRFEGRDSPIPVFINEAAYVEKHIAMSLTCREVCPLPEQWQGALQQL
VDC
>Mature_323_residues
MVVPFAAIFGQAEDCDRILMSGLQVLLVAGTHGNEINAPWLLDQWSQTPELINTHGVAVVPVIGNPEAFALGRRYLDCDL
NRSFRLDLLRSPSILDREVVRAKQLLSFFGPEGSTPCQIVIDLHSTTSAMGSTLVVYGRRPADLALAALIQARLGLPIYL
HDGDDDQQGFLVERWPCGLVIEIGPVPQGLLKACIIEQTRLAVQACLEALSSISSGSPTYPDQFVVHSHLGSLDLPRDGL
GQPAACVHPYLQGRDWQPLQMGAPLFLRPDGEVFRFEGRDSPIPVFINEAAYVEKHIAMSLTCREVCPLPEQWQGALQQL
VDC

Specific function: Unknown

COG id: COG2988

COG function: function code E; Succinylglutamate desuccinylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AspA/AstE family. Aspartoacylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557335, Length=290, Percent_Identity=37.2413793103448, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI189339202, Length=290, Percent_Identity=37.2413793103448, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI18087825, Length=295, Percent_Identity=35.2542372881356, Blast_Score=168, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016708
- InterPro:   IPR007036 [H]

Pfam domain/function: PF04952 AstE_AspA [H]

EC number: =3.5.1.15 [H]

Molecular weight: Translated: 35380; Mature: 35380

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVPFAAIFGQAEDCDRILMSGLQVLLVAGTHGNEINAPWLLDQWSQTPELINTHGVAVV
CCCCCHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCCCEEHHCCCCCCHHHCCCCEEEE
PVIGNPEAFALGRRYLDCDLNRSFRLDLLRSPSILDREVVRAKQLLSFFGPEGSTPCQIV
EEECCCCHHHHCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEE
IDLHSTTSAMGSTLVVYGRRPADLALAALIQARLGLPIYLHDGDDDQQGFLVERWPCGLV
EEECCCHHHCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCEE
IEIGPVPQGLLKACIIEQTRLAVQACLEALSSISSGSPTYPDQFVVHSHLGSLDLPRDGL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCC
GQPAACVHPYLQGRDWQPLQMGAPLFLRPDGEVFRFEGRDSPIPVFINEAAYVEKHIAMS
CCCHHHHHHHHCCCCCCCHHCCCCEEECCCCCEEEECCCCCCCCEEECCHHHHHHHHHHE
LTCREVCPLPEQWQGALQQLVDC
EEHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVVPFAAIFGQAEDCDRILMSGLQVLLVAGTHGNEINAPWLLDQWSQTPELINTHGVAVV
CCCCCHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCCCEEHHCCCCCCHHHCCCCEEEE
PVIGNPEAFALGRRYLDCDLNRSFRLDLLRSPSILDREVVRAKQLLSFFGPEGSTPCQIV
EEECCCCHHHHCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEE
IDLHSTTSAMGSTLVVYGRRPADLALAALIQARLGLPIYLHDGDDDQQGFLVERWPCGLV
EEECCCHHHCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCEE
IEIGPVPQGLLKACIIEQTRLAVQACLEALSSISSGSPTYPDQFVVHSHLGSLDLPRDGL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCC
GQPAACVHPYLQGRDWQPLQMGAPLFLRPDGEVFRFEGRDSPIPVFINEAAYVEKHIAMS
CCCHHHHHHHHCCCCCCCHHCCCCEEECCCCCEEEECCCCCCCCEEECCHHHHHHHHHHE
LTCREVCPLPEQWQGALQQLVDC
EEHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]