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The map label for this gene is msrB [H]

Identifier: 124022035

GI number: 124022035

Start: 335409

End: 335843

Strand: Direct

Name: msrB [H]

Synonym: P9303_03241

Alternate gene names: 124022035

Gene position: 335409-335843 (Clockwise)

Preceding gene: 124022034

Following gene: 124022039

Centisome position: 12.5

GC content: 54.02

Gene sequence:

>435_bases
ATGTCCAGGTCTGATTCCTCCGCTTCCGATTCAGTGGATTGGATCAAGCTCAGCCCTGAGGAATGGCAGGCCAGGTTGAC
TCGTGAGCAGTATCAGGTTGCCCGTAAGGGAGGCACGGAGCGAGCATTTACAGGTGCTTATTGGAACCACAAGGCAGCAG
GGATGTATTGCTGTGTCTGTTGTGGAGCCCCACTCTTCAGCTCAGCGACAAAATTCGATTCAGGCACTGGTTGGCCGAGC
TTTTCCGATGGAGTCAAGGCAGGTGCGATTACCACCCATCGGGACACGAGTCATGGAATGGAGCGTACTGAGATCAACTG
TTCTCGCTGTGGGGCTCATCTGGGCCATGTCTTTAACGACGGACCAGCTCCTACAGGTCAGAGGTACTGCGTGAACAGCG
CTTCGCTTGATTTTTCGGAGCAGTCAGAGGTTTGA

Upstream 100 bases:

>100_bases
ACTGGTTCAGCAGGTGCGTCGTTTGCTGCCCAAAGCTCTCGGTGCTTTTTAGATTCGAAGGCTGTTTAGGGTCTTGCAGG
TCCTCTTTCTTTTCTCTTCC

Downstream 100 bases:

>100_bases
TTTGAATCGAACGTCACCAAGGGTCGTCCAGTTCGGTGCCATTACGGCGCGGTGGGGGCTCCTCCACCTCTGCATCTCGG
TCTCGGCCAGCTTGATCACG

Product: methionine sulfoxide reductase family protein

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MSRSDSSASDSVDWIKLSPEEWQARLTREQYQVARKGGTERAFTGAYWNHKAAGMYCCVCCGAPLFSSATKFDSGTGWPS
FSDGVKAGAITTHRDTSHGMERTEINCSRCGAHLGHVFNDGPAPTGQRYCVNSASLDFSEQSEV

Sequences:

>Translated_144_residues
MSRSDSSASDSVDWIKLSPEEWQARLTREQYQVARKGGTERAFTGAYWNHKAAGMYCCVCCGAPLFSSATKFDSGTGWPS
FSDGVKAGAITTHRDTSHGMERTEINCSRCGAHLGHVFNDGPAPTGQRYCVNSASLDFSEQSEV
>Mature_143_residues
SRSDSSASDSVDWIKLSPEEWQARLTREQYQVARKGGTERAFTGAYWNHKAAGMYCCVCCGAPLFSSATKFDSGTGWPSF
SDGVKAGAITTHRDTSHGMERTEINCSRCGAHLGHVFNDGPAPTGQRYCVNSASLDFSEQSEV

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=125, Percent_Identity=57.6, Blast_Score=160, Evalue=4e-40,
Organism=Homo sapiens, GI301336162, Length=125, Percent_Identity=57.6, Blast_Score=160, Evalue=4e-40,
Organism=Homo sapiens, GI73089054, Length=125, Percent_Identity=57.6, Blast_Score=160, Evalue=4e-40,
Organism=Homo sapiens, GI37620216, Length=125, Percent_Identity=57.6, Blast_Score=160, Evalue=5e-40,
Organism=Homo sapiens, GI117606353, Length=131, Percent_Identity=53.4351145038168, Blast_Score=145, Evalue=1e-35,
Organism=Homo sapiens, GI7706511, Length=94, Percent_Identity=37.2340425531915, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788077, Length=125, Percent_Identity=54.4, Blast_Score=143, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17553450, Length=123, Percent_Identity=51.219512195122, Blast_Score=129, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI115532676, Length=123, Percent_Identity=51.219512195122, Blast_Score=129, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6319816, Length=126, Percent_Identity=46.8253968253968, Blast_Score=112, Evalue=2e-26,
Organism=Drosophila melanogaster, GI221378664, Length=125, Percent_Identity=55.2, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI221378662, Length=132, Percent_Identity=52.2727272727273, Blast_Score=152, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24645799, Length=127, Percent_Identity=52.755905511811, Blast_Score=150, Evalue=4e-37,
Organism=Drosophila melanogaster, GI45553335, Length=127, Percent_Identity=52.755905511811, Blast_Score=149, Evalue=4e-37,
Organism=Drosophila melanogaster, GI21356369, Length=127, Percent_Identity=52.755905511811, Blast_Score=149, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24645801, Length=138, Percent_Identity=49.2753623188406, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24645804, Length=138, Percent_Identity=49.2753623188406, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15654; Mature: 15523

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSDSSASDSVDWIKLSPEEWQARLTREQYQVARKGGTERAFTGAYWNHKAAGMYCCVC
CCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEHHH
CGAPLFSSATKFDSGTGWPSFSDGVKAGAITTHRDTSHGMERTEINCSRCGAHLGHVFND
CCCHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GPAPTGQRYCVNSASLDFSEQSEV
CCCCCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SRSDSSASDSVDWIKLSPEEWQARLTREQYQVARKGGTERAFTGAYWNHKAAGMYCCVC
CCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEHHH
CGAPLFSSATKFDSGTGWPSFSDGVKAGAITTHRDTSHGMERTEINCSRCGAHLGHVFND
CCCHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GPAPTGQRYCVNSASLDFSEQSEV
CCCCCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA