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The map label for this gene is comM [H]

Identifier: 124022024

GI number: 124022024

Start: 325482

End: 327068

Strand: Reverse

Name: comM [H]

Synonym: P9303_03131

Alternate gene names: 124022024

Gene position: 327068-325482 (Counterclockwise)

Preceding gene: 124022028

Following gene: 124022021

Centisome position: 12.19

GC content: 55.58

Gene sequence:

>1587_bases
ATGCTGGCACGTTGCCTGAGTGGTTCTCTGCATGGCATTGAAGCCCTAGCCGTCACTGTGGAAGTGGATCTAGTGCCTGG
GCTGCCAGGGCTGCAACTGGTAGGGCTACCCGACGCCGCCATACAGGAGTCTCGTGAGCGAGTGCGATCAGCACTCCGCA
ACAGTGGCTTTCGCGGGCCACTCGTGCGAGTCGTGGTGAACCTAGCTCCTGCCGATCTTCGTAAAGAGGGACCTTCCTTT
GATCTACCTATCGCCCTGGCCCTATTGGTAGCAAGTGGCCAGCTGGATGGTCCGTTGCTTGCCAATCTCTGCTGCGCTGG
AGAACTCGGACTCGATGGCAGCTTGCGGCCCTGCAGAGGAATCCTTGCCATCGCCAACCTGGCCGCCACGCAAAACGTAC
GAGCGTTAGTGGTGCCATCAGCCAATGCCGCAGAAGCAAGCCTTGTGCCTGGCTTAACAGTACGAGCTGCTCATTCCCTC
AGCGAGGTTGTGGATCTATTGCACCAACCCCAACCACTAGCACCTAAACACATCTCCAAAGCGGCCGTCACGGCAAAAAT
CACGCGCAGACCAAACGATCAACTTCATCCACTGCTTGATTGCGCCTTGGGCCATAAAGCCCTTGCCTTGGCTGCTGCCG
GGGGCCATCACCTCCTGATGGTGGGGCCACCTGGCTGTGGGAAAACCCTTTTGGCTCAACATTTAGCCCAGCTGCTGCCG
CCGCTCACGCGCCAAGAGGCCTTGGAAATCACCAGTATTCACTCTGTGGCAGGAATGCTGAAGAGCACTCCCCAGTTAAT
GCAACAGCGACCCTTCCGGGCTCCCCATCACAGTTGCACGATTGCTGCCCTCGTTGGAGGCGGTGCAAACCCCAGGCCAG
GAGAACTGAGCCTCGCCCATGGTGGTGTGTTGTTTCTCGATGAACTAGCTGAATTTCCACGCAAAGTTCTCGACCAACTT
CGACAACCACTCGAGGAAGGAGTCATTCGTCTGAGTCGAGCCAGGCAGACATGTGCCTTCCCTTCTCAAATCACCCTTGT
AGCAGCAACCAATCCCTGCCCATGCGGGTGGTTTGGAGATGAAGAGCATCCTTGCCGCTGTAGCCAATCCCAACGCCAGC
GGTATTGGAGCCGCCTCTCTGGCCCCTTATTGGATCGCCTGGATTTACAACTGCGCCTCAAGCACCTACCCGCAGCTCAA
CTGCGCAAATCGGTTACCGGCTTCACTCCCACTGATCTCAATGATCAAAAGTTAATAGGCATCGAGCAGATCTTGCGCGC
GCGCGCGCGGATGCTTGTTCGCAATCCTGATGGAAAGCTCAATCGTGACCTCTCAGCCCAGGATTTAGGACAAATCGGCC
AGCTGGATGAAAAGGCTCTAGAGCTCTGGGAGCAAGTTGTGAATCACCGCAGACTCAGTGCACGCAGCGGTCTAAGGATT
CTTAGAGTCGCTAGGTCTCTGGCAGATCTTCATGATCAAGACAAAGTCAATAAAAGTGCGATAGCGGAAACAATGTGTTT
CCGTAGTTTTGATTGTGGCGATGCCAAAGAAGATTTCGCCATCATTGCCAAGCAACTCGCCAGCTAA

Upstream 100 bases:

>100_bases
ACCGCGAAGCATCTGGCCAAAAATGGTGTCACCAGCCATTGAGTCACAGTCTGAGGATGGGACGGCTGGGGCATGAAATC
CATGCACCGTCTGATTACAA

Downstream 100 bases:

>100_bases
TTTCCTTCGCCTTCAGCAATCATCCGTATCAAGCTTATTCCTACAAGGCCAAAATCGAATCAGATAGAGTTGATCATTAA
TCTTCGCTAAGATCATTCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MLARCLSGSLHGIEALAVTVEVDLVPGLPGLQLVGLPDAAIQESRERVRSALRNSGFRGPLVRVVVNLAPADLRKEGPSF
DLPIALALLVASGQLDGPLLANLCCAGELGLDGSLRPCRGILAIANLAATQNVRALVVPSANAAEASLVPGLTVRAAHSL
SEVVDLLHQPQPLAPKHISKAAVTAKITRRPNDQLHPLLDCALGHKALALAAAGGHHLLMVGPPGCGKTLLAQHLAQLLP
PLTRQEALEITSIHSVAGMLKSTPQLMQQRPFRAPHHSCTIAALVGGGANPRPGELSLAHGGVLFLDELAEFPRKVLDQL
RQPLEEGVIRLSRARQTCAFPSQITLVAATNPCPCGWFGDEEHPCRCSQSQRQRYWSRLSGPLLDRLDLQLRLKHLPAAQ
LRKSVTGFTPTDLNDQKLIGIEQILRARARMLVRNPDGKLNRDLSAQDLGQIGQLDEKALELWEQVVNHRRLSARSGLRI
LRVARSLADLHDQDKVNKSAIAETMCFRSFDCGDAKEDFAIIAKQLAS

Sequences:

>Translated_528_residues
MLARCLSGSLHGIEALAVTVEVDLVPGLPGLQLVGLPDAAIQESRERVRSALRNSGFRGPLVRVVVNLAPADLRKEGPSF
DLPIALALLVASGQLDGPLLANLCCAGELGLDGSLRPCRGILAIANLAATQNVRALVVPSANAAEASLVPGLTVRAAHSL
SEVVDLLHQPQPLAPKHISKAAVTAKITRRPNDQLHPLLDCALGHKALALAAAGGHHLLMVGPPGCGKTLLAQHLAQLLP
PLTRQEALEITSIHSVAGMLKSTPQLMQQRPFRAPHHSCTIAALVGGGANPRPGELSLAHGGVLFLDELAEFPRKVLDQL
RQPLEEGVIRLSRARQTCAFPSQITLVAATNPCPCGWFGDEEHPCRCSQSQRQRYWSRLSGPLLDRLDLQLRLKHLPAAQ
LRKSVTGFTPTDLNDQKLIGIEQILRARARMLVRNPDGKLNRDLSAQDLGQIGQLDEKALELWEQVVNHRRLSARSGLRI
LRVARSLADLHDQDKVNKSAIAETMCFRSFDCGDAKEDFAIIAKQLAS
>Mature_528_residues
MLARCLSGSLHGIEALAVTVEVDLVPGLPGLQLVGLPDAAIQESRERVRSALRNSGFRGPLVRVVVNLAPADLRKEGPSF
DLPIALALLVASGQLDGPLLANLCCAGELGLDGSLRPCRGILAIANLAATQNVRALVVPSANAAEASLVPGLTVRAAHSL
SEVVDLLHQPQPLAPKHISKAAVTAKITRRPNDQLHPLLDCALGHKALALAAAGGHHLLMVGPPGCGKTLLAQHLAQLLP
PLTRQEALEITSIHSVAGMLKSTPQLMQQRPFRAPHHSCTIAALVGGGANPRPGELSLAHGGVLFLDELAEFPRKVLDQL
RQPLEEGVIRLSRARQTCAFPSQITLVAATNPCPCGWFGDEEHPCRCSQSQRQRYWSRLSGPLLDRLDLQLRLKHLPAAQ
LRKSVTGFTPTDLNDQKLIGIEQILRARARMLVRNPDGKLNRDLSAQDLGQIGQLDEKALELWEQVVNHRRLSARSGLRI
LRVARSLADLHDQDKVNKSAIAETMCFRSFDCGDAKEDFAIIAKQLAS

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=501, Percent_Identity=40.9181636726547, Blast_Score=345, Evalue=4e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 56839; Mature: 56839

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS00626 RCC1_2 ; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARCLSGSLHGIEALAVTVEVDLVPGLPGLQLVGLPDAAIQESRERVRSALRNSGFRGP
CCCHHHCCCCCCEEEEEEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCH
LVRVVVNLAPADLRKEGPSFDLPIALALLVASGQLDGPLLANLCCAGELGLDGSLRPCRG
HHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHH
ILAIANLAATQNVRALVVPSANAAEASLVPGLTVRAAHSLSEVVDLLHQPQPLAPKHISK
HHHHHHHHHCCCCEEEEECCCCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AAVTAKITRRPNDQLHPLLDCALGHKALALAAAGGHHLLMVGPPGCGKTLLAQHLAQLLP
HHHHHHHHCCCCCHHHHHHHHHHCCHHHEEEECCCCEEEEECCCCCCHHHHHHHHHHHCC
PLTRQEALEITSIHSVAGMLKSTPQLMQQRPFRAPHHSCTIAALVGGGANPRPGELSLAH
CCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCEEECC
GGVLFLDELAEFPRKVLDQLRQPLEEGVIRLSRARQTCAFPSQITLVAATNPCPCGWFGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
EEHPCRCSQSQRQRYWSRLSGPLLDRLDLQLRLKHLPAAQLRKSVTGFTPTDLNDQKLIG
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHH
IEQILRARARMLVRNPDGKLNRDLSAQDLGQIGQLDEKALELWEQVVNHRRLSARSGLRI
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRVARSLADLHDQDKVNKSAIAETMCFRSFDCGDAKEDFAIIAKQLAS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLARCLSGSLHGIEALAVTVEVDLVPGLPGLQLVGLPDAAIQESRERVRSALRNSGFRGP
CCCHHHCCCCCCEEEEEEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCH
LVRVVVNLAPADLRKEGPSFDLPIALALLVASGQLDGPLLANLCCAGELGLDGSLRPCRG
HHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHH
ILAIANLAATQNVRALVVPSANAAEASLVPGLTVRAAHSLSEVVDLLHQPQPLAPKHISK
HHHHHHHHHCCCCEEEEECCCCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AAVTAKITRRPNDQLHPLLDCALGHKALALAAAGGHHLLMVGPPGCGKTLLAQHLAQLLP
HHHHHHHHCCCCCHHHHHHHHHHCCHHHEEEECCCCEEEEECCCCCCHHHHHHHHHHHCC
PLTRQEALEITSIHSVAGMLKSTPQLMQQRPFRAPHHSCTIAALVGGGANPRPGELSLAH
CCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCEEECC
GGVLFLDELAEFPRKVLDQLRQPLEEGVIRLSRARQTCAFPSQITLVAATNPCPCGWFGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
EEHPCRCSQSQRQRYWSRLSGPLLDRLDLQLRLKHLPAAQLRKSVTGFTPTDLNDQKLIG
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHH
IEQILRARARMLVRNPDGKLNRDLSAQDLGQIGQLDEKALELWEQVVNHRRLSARSGLRI
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRVARSLADLHDQDKVNKSAIAETMCFRSFDCGDAKEDFAIIAKQLAS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]