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The map label for this gene is hflX [H]

Identifier: 124021970

GI number: 124021970

Start: 269032

End: 270708

Strand: Reverse

Name: hflX [H]

Synonym: P9303_02571

Alternate gene names: 124021970

Gene position: 270708-269032 (Counterclockwise)

Preceding gene: 124021971

Following gene: 124021969

Centisome position: 10.09

GC content: 55.34

Gene sequence:

>1677_bases
TTGAAACAAGCCCACCTAGCTGGCCGCACCAAGGGACTACGCCCTTCACAACAAAGACAATTAGAACGCCTCAGCCACCG
CAGGCATCCCGAAAGGGAAGGCGCCGATCAGCTAACCCTGGAACGGCTAGCTGAACAGGTGATTGAGCTATGCCAACCAC
TCCATTTAGTGCTGGATAGCCGTGGATTGTGCCGCCTTCTTTGGGTCGGTCCTCTCGATGGATCCGGCCAACTTCTCGCC
CATCTTCCTGAATCACCCCGTCGCAAGACCGCTGGATGGCGCTTAATCAGCTGCTCTCTAACGCTTCAGCGAAACAACCT
CAGGCCAGAACAACATGATGCAATCGTGGCACTCGATCTAGCACCGAACTCCTGGCTACGTTTTGCCCCCACAGCAGATC
GAGGAGGTCGCAGGATTGCTGCCCTCTGGCAACCAGATCCAAAGGAGATCTCGGGATGGAGCTTGATCGAAGCCAACGGA
CTAAGCGAGCTCTGCCAACACAGCCAAGGATCAACCGCCAAGCCAGAAGTCAACCCCCTACCGTCAAAGGACGGTAGGGA
ACGGGTCCTACTACTTACCCTTACGGGACCAAAGCAAAGCCGCAGCGAACGCGACCTTGCTGAGCTCGAGGGGTTGGTGC
GCAGTGCAGGGGGGCATCCTGTAGCAGTTGTGCGACAAAAGCAGGGGGCTCCTAATCCTCAGACCCTCTGGGGCAAGGGG
AAACTACAAGAGACCGCCTTGGAAGTTCGGCGACATAGCGCTTCTCTAGTGATCACAGACCGTGAGCTCAGTCCTGTTCA
AGTCAGGAATCTGGAGCGATATCTCGACTGCCCTGTCATGGATCGAAGTGAATTAATCCTAGACATCTTTGCCCAGCGCG
CCTCTAGTGCAGCAGGCCGCCTTCAAGTGGAACTAGCCCAACTTCGCTATCGCATGCCAAGGCTGATGGGGCGAGGTCGC
AGCCTATCCCGTCAGGGAGGTGGCATCGGCACACGCGGGCCCGGAGAGACCCAACTCGAGAAAGACCGGCGTGCGATTAC
ACGACGCATCGAGCACTTGTTACGTGAGGTACGGCAACTGCAAAACCATCGCGCCCGACTACGCAACCGCAGGGAAGGTC
TGCCAAGGGTTGCACTCGTGGGTTATACCAATGCGGGGAAATCATCCCTACTCAATGCTCTCTGCAGTCGAAACGAGCAC
AGCAAAGTGCTGGCAGAGAACAAACTGTTTGCAACCTTGGATCCAACCACCCGACGATTCTTGATTCCTCAGACAGGTGG
AAAACCCCTTGAGCTTCTTATCACAGACACTGTGGGCTTCATCCGTGAACTGCCAGCGCCATTAGTGGAAGCCTTTCGGG
CCACTCTGGAGGAAACTCTTGAAGCCGATCTCCTCCTAGTGGTTGTGGACTTGTCAGACACAGACTGGCAAGCCCAACTT
GACACAGTGCATCAGTTGCTTAATTCCCTTGGCGCAGAATCAATCCGGCAGGTGATAGCCAATCAAATTGATCGTTGTGA
TACCAGTGCACTTGAGGAAATCCGCAGCATCGACCCGAAGGTGATTTATCTCTCCGCGGCCTCAGGTGCCGGGCTGCAAG
GACTAAAACACTGGCTGAAGGATCAATTCTGGGGTCACAAAGCAGAATCGGCCCCTCTGCCTTCTGTAAATACCTAA

Upstream 100 bases:

>100_bases
CAGGTCCTCTGGCTTTCCAAATACGCCGGGGTGCCTATCTAACAAAACTACCTGGATTGTCTCTAGGCCTGCGCTCAGGC
GGAGCCTGGCTGCTCGGACA

Downstream 100 bases:

>100_bases
CTATGGCTGTGCTGAGCACCGCTATTCAAAACCCCCAAGCCCTCATCACCCTGGCGGTGTTGTTGCTGGCGGTGGTGCTC
TTCATCAGCGGTGCCCTTGC

Product: GTP-binding protein, transport associated

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MKQAHLAGRTKGLRPSQQRQLERLSHRRHPEREGADQLTLERLAEQVIELCQPLHLVLDSRGLCRLLWVGPLDGSGQLLA
HLPESPRRKTAGWRLISCSLTLQRNNLRPEQHDAIVALDLAPNSWLRFAPTADRGGRRIAALWQPDPKEISGWSLIEANG
LSELCQHSQGSTAKPEVNPLPSKDGRERVLLLTLTGPKQSRSERDLAELEGLVRSAGGHPVAVVRQKQGAPNPQTLWGKG
KLQETALEVRRHSASLVITDRELSPVQVRNLERYLDCPVMDRSELILDIFAQRASSAAGRLQVELAQLRYRMPRLMGRGR
SLSRQGGGIGTRGPGETQLEKDRRAITRRIEHLLREVRQLQNHRARLRNRREGLPRVALVGYTNAGKSSLLNALCSRNEH
SKVLAENKLFATLDPTTRRFLIPQTGGKPLELLITDTVGFIRELPAPLVEAFRATLEETLEADLLLVVVDLSDTDWQAQL
DTVHQLLNSLGAESIRQVIANQIDRCDTSALEEIRSIDPKVIYLSAASGAGLQGLKHWLKDQFWGHKAESAPLPSVNT

Sequences:

>Translated_558_residues
MKQAHLAGRTKGLRPSQQRQLERLSHRRHPEREGADQLTLERLAEQVIELCQPLHLVLDSRGLCRLLWVGPLDGSGQLLA
HLPESPRRKTAGWRLISCSLTLQRNNLRPEQHDAIVALDLAPNSWLRFAPTADRGGRRIAALWQPDPKEISGWSLIEANG
LSELCQHSQGSTAKPEVNPLPSKDGRERVLLLTLTGPKQSRSERDLAELEGLVRSAGGHPVAVVRQKQGAPNPQTLWGKG
KLQETALEVRRHSASLVITDRELSPVQVRNLERYLDCPVMDRSELILDIFAQRASSAAGRLQVELAQLRYRMPRLMGRGR
SLSRQGGGIGTRGPGETQLEKDRRAITRRIEHLLREVRQLQNHRARLRNRREGLPRVALVGYTNAGKSSLLNALCSRNEH
SKVLAENKLFATLDPTTRRFLIPQTGGKPLELLITDTVGFIRELPAPLVEAFRATLEETLEADLLLVVVDLSDTDWQAQL
DTVHQLLNSLGAESIRQVIANQIDRCDTSALEEIRSIDPKVIYLSAASGAGLQGLKHWLKDQFWGHKAESAPLPSVNT
>Mature_558_residues
MKQAHLAGRTKGLRPSQQRQLERLSHRRHPEREGADQLTLERLAEQVIELCQPLHLVLDSRGLCRLLWVGPLDGSGQLLA
HLPESPRRKTAGWRLISCSLTLQRNNLRPEQHDAIVALDLAPNSWLRFAPTADRGGRRIAALWQPDPKEISGWSLIEANG
LSELCQHSQGSTAKPEVNPLPSKDGRERVLLLTLTGPKQSRSERDLAELEGLVRSAGGHPVAVVRQKQGAPNPQTLWGKG
KLQETALEVRRHSASLVITDRELSPVQVRNLERYLDCPVMDRSELILDIFAQRASSAAGRLQVELAQLRYRMPRLMGRGR
SLSRQGGGIGTRGPGETQLEKDRRAITRRIEHLLREVRQLQNHRARLRNRREGLPRVALVGYTNAGKSSLLNALCSRNEH
SKVLAENKLFATLDPTTRRFLIPQTGGKPLELLITDTVGFIRELPAPLVEAFRATLEETLEADLLLVVVDLSDTDWQAQL
DTVHQLLNSLGAESIRQVIANQIDRCDTSALEEIRSIDPKVIYLSAASGAGLQGLKHWLKDQFWGHKAESAPLPSVNT

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=237, Percent_Identity=32.4894514767932, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI310133116, Length=220, Percent_Identity=33.1818181818182, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI310124269, Length=212, Percent_Identity=33.0188679245283, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI310124267, Length=212, Percent_Identity=33.0188679245283, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI310124171, Length=212, Percent_Identity=33.0188679245283, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI310124169, Length=212, Percent_Identity=33.0188679245283, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1790615, Length=356, Percent_Identity=43.8202247191011, Blast_Score=254, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17561038, Length=317, Percent_Identity=29.0220820189274, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24650079, Length=357, Percent_Identity=35.2941176470588, Blast_Score=128, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 62224; Mature: 62224

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQAHLAGRTKGLRPSQQRQLERLSHRRHPEREGADQLTLERLAEQVIELCQPLHLVLDS
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RGLCRLLWVGPLDGSGQLLAHLPESPRRKTAGWRLISCSLTLQRNNLRPEQHDAIVALDL
CCCEEEEEECCCCCCCCEEEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCEEEEEE
APNSWLRFAPTADRGGRRIAALWQPDPKEISGWSLIEANGLSELCQHSQGSTAKPEVNPL
CCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCC
PSKDGRERVLLLTLTGPKQSRSERDLAELEGLVRSAGGHPVAVVRQKQGAPNPQTLWGKG
CCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCC
KLQETALEVRRHSASLVITDRELSPVQVRNLERYLDCPVMDRSELILDIFAQRASSAAGR
CHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCH
LQVELAQLRYRMPRLMGRGRSLSRQGGGIGTRGPGETQLEKDRRAITRRIEHLLREVRQL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QNHRARLRNRREGLPRVALVGYTNAGKSSLLNALCSRNEHSKVLAENKLFATLDPTTRRF
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCEE
LIPQTGGKPLELLITDTVGFIRELPAPLVEAFRATLEETLEADLLLVVVDLSDTDWQAQL
EEECCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHH
DTVHQLLNSLGAESIRQVIANQIDRCDTSALEEIRSIDPKVIYLSAASGAGLQGLKHWLK
HHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
DQFWGHKAESAPLPSVNT
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQAHLAGRTKGLRPSQQRQLERLSHRRHPEREGADQLTLERLAEQVIELCQPLHLVLDS
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RGLCRLLWVGPLDGSGQLLAHLPESPRRKTAGWRLISCSLTLQRNNLRPEQHDAIVALDL
CCCEEEEEECCCCCCCCEEEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCEEEEEE
APNSWLRFAPTADRGGRRIAALWQPDPKEISGWSLIEANGLSELCQHSQGSTAKPEVNPL
CCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCC
PSKDGRERVLLLTLTGPKQSRSERDLAELEGLVRSAGGHPVAVVRQKQGAPNPQTLWGKG
CCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCC
KLQETALEVRRHSASLVITDRELSPVQVRNLERYLDCPVMDRSELILDIFAQRASSAAGR
CHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCH
LQVELAQLRYRMPRLMGRGRSLSRQGGGIGTRGPGETQLEKDRRAITRRIEHLLREVRQL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QNHRARLRNRREGLPRVALVGYTNAGKSSLLNALCSRNEHSKVLAENKLFATLDPTTRRF
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCEE
LIPQTGGKPLELLITDTVGFIRELPAPLVEAFRATLEETLEADLLLVVVDLSDTDWQAQL
EEECCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHH
DTVHQLLNSLGAESIRQVIANQIDRCDTSALEEIRSIDPKVIYLSAASGAGLQGLKHWLK
HHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
DQFWGHKAESAPLPSVNT
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]