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The map label for this gene is phoP [H]

Identifier: 124021896

GI number: 124021896

Start: 202013

End: 202885

Strand: Direct

Name: phoP [H]

Synonym: P9303_01831

Alternate gene names: 124021896

Gene position: 202013-202885 (Clockwise)

Preceding gene: 124021895

Following gene: 124021897

Centisome position: 7.53

GC content: 54.41

Gene sequence:

>873_bases
ATGTCACATCCGGGGGGTTCATCTCAGTTCCAAAGCAATGCTGGGTCTGAGACGCAGGCTCCCGGGAATCCGAAGGCAAC
CATCCTTGTCGTTGACGATGAGCCAGCAGTCCTCCGGATTTTGGTCATGCGACTTCAACTGGCTGGCTATCGGGTGATTT
GTGCCGAGGACGGGGAAGAGGCCCTTGAGATTTTTCATCGAGAACAGCCTGACTTGCTTGTGCTCGATGTGATGCTGCCC
AGGCTCGATGGTTTTGCTGTTTGTAGAAGGCTTAGGGCTGAGTCTTGTGTGCCGATTATTTTCCTCTCAGCATTAGAGGC
GATTTCTGAACGTGTGGCTGGACTTGATCTTGGGGCAGATGATTACATTCCTAAGCCCTTTAGTCCCAAGGAACTTGAGG
CTCGTATTGCCACAATTCTGCGTCGGGTTGGTCCAGGGTCCGCTACGGCTGAAATCAGAGATCTGCCAGTTGGGCAGGGT
GTTATGCGAGTTGGTGATTTGGTGGTTGACACCAATCGCCGCCAGGTGAGTCGTGCAGGAGAGCGTATTGGCCTCACCTA
CACCGAATTCAGTCTTTTGGAACTGTTGTTCCGTGAACCTGGACGGGTGGTACCCAGGGCCGAAATCTTGGAGCAGCTCT
GGGGTTATCCCCCTCGCCGTGCGGCCGACTTGCGTGTGGTCGATGTTTATGTAGCTCGTTTGCGTGGCAAGCTCGAGCCA
GACCCGCGCAATCCAGAGCTAATCCTTACGGTTCGTGGAATTGGTTACTCCTCCCAGCGCGTTGGGGATATTCCTGCTTC
TGCTTCTGCTTCTGCTTCTGCTTCTGCTCCTGCTTCTGCTCCTGCTTCTGCTTCGGTTGCCGTTGCGAGTTGA

Upstream 100 bases:

>100_bases
TTCTTAAATAAATAGAAAAACTGCTATTTCCCAGGGGTCTTAGCGATTTTTACTTAAGGCGGAAGGGTAAGGTTGTGTTT
CTTCATGAGGAAATGCTCAT

Downstream 100 bases:

>100_bases
TTAAGTCGATGGGGTGAGTAGAGCAACGACTCCATCGACCGGCAAGATGGCGAGGTCAGTCCTGAGTGCCTTGTCTGAGC
TGCGTGAGACTCGCCTGGAA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSHPGGSSQFQSNAGSETQAPGNPKATILVVDDEPAVLRILVMRLQLAGYRVICAEDGEEALEIFHREQPDLLVLDVMLP
RLDGFAVCRRLRAESCVPIIFLSALEAISERVAGLDLGADDYIPKPFSPKELEARIATILRRVGPGSATAEIRDLPVGQG
VMRVGDLVVDTNRRQVSRAGERIGLTYTEFSLLELLFREPGRVVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEP
DPRNPELILTVRGIGYSSQRVGDIPASASASASASAPASAPASASVAVAS

Sequences:

>Translated_290_residues
MSHPGGSSQFQSNAGSETQAPGNPKATILVVDDEPAVLRILVMRLQLAGYRVICAEDGEEALEIFHREQPDLLVLDVMLP
RLDGFAVCRRLRAESCVPIIFLSALEAISERVAGLDLGADDYIPKPFSPKELEARIATILRRVGPGSATAEIRDLPVGQG
VMRVGDLVVDTNRRQVSRAGERIGLTYTEFSLLELLFREPGRVVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEP
DPRNPELILTVRGIGYSSQRVGDIPASASASASASAPASAPASASVAVAS
>Mature_289_residues
SHPGGSSQFQSNAGSETQAPGNPKATILVVDDEPAVLRILVMRLQLAGYRVICAEDGEEALEIFHREQPDLLVLDVMLPR
LDGFAVCRRLRAESCVPIIFLSALEAISERVAGLDLGADDYIPKPFSPKELEARIATILRRVGPGSATAEIRDLPVGQGV
MRVGDLVVDTNRRQVSRAGERIGLTYTEFSLLELLFREPGRVVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEPD
PRNPELILTVRGIGYSSQRVGDIPASASASASASAPASAPASASVAVAS

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=42.1739130434783, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=38.4279475982533, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=37.6623376623377, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1790860, Length=238, Percent_Identity=37.3949579831933, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=37.6068376068376, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=36.5217391304348, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=36.2068965517241, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=36.3636363636364, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=38.695652173913, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=32.4675324675325, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=35.0649350649351, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=33.4763948497854, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=33.1896551724138, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=34.1991341991342, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788550, Length=129, Percent_Identity=34.8837209302326, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=31.4814814814815, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=153, Percent_Identity=33.9869281045752, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI145693157, Length=122, Percent_Identity=30.327868852459, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 31255; Mature: 31124

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHPGGSSQFQSNAGSETQAPGNPKATILVVDDEPAVLRILVMRLQLAGYRVICAEDGEE
CCCCCCCCCHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCHH
ALEIFHREQPDLLVLDVMLPRLDGFAVCRRLRAESCVPIIFLSALEAISERVAGLDLGAD
HHHHHHCCCCCEEEEEHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
DYIPKPFSPKELEARIATILRRVGPGSATAEIRDLPVGQGVMRVGDLVVDTNRRQVSRAG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCEEEECCHHHHHHHH
ERIGLTYTEFSLLELLFREPGRVVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEP
HHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC
DPRNPELILTVRGIGYSSQRVGDIPASASASASASAPASAPASASVAVAS
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure 
SHPGGSSQFQSNAGSETQAPGNPKATILVVDDEPAVLRILVMRLQLAGYRVICAEDGEE
CCCCCCCCHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCHH
ALEIFHREQPDLLVLDVMLPRLDGFAVCRRLRAESCVPIIFLSALEAISERVAGLDLGAD
HHHHHHCCCCCEEEEEHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
DYIPKPFSPKELEARIATILRRVGPGSATAEIRDLPVGQGVMRVGDLVVDTNRRQVSRAG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCEEEECCHHHHHHHH
ERIGLTYTEFSLLELLFREPGRVVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEP
HHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC
DPRNPELILTVRGIGYSSQRVGDIPASASASASASAPASAPASASVAVAS
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]