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The map label for this gene is lytB [H]

Identifier: 124021777

GI number: 124021777

Start: 57045

End: 58628

Strand: Direct

Name: lytB [H]

Synonym: P9303_00621

Alternate gene names: 124021777

Gene position: 57045-58628 (Clockwise)

Preceding gene: 124021776

Following gene: 124021778

Centisome position: 2.13

GC content: 55.43

Gene sequence:

>1584_bases
TTGGCCAAGACTTTTCATCGTTCGCTGATTCGCTCTAAGCAAGTCATGAGTGGCGCCCTGGTCTTGCTTGGTGTTTGCAC
GGTGGGCTGTGAGGCCCAAGAGGTGATTCCACCAGTTGGTTCTGTTGGTATGCCTACTCATCAGGCGGTACAAGCTCCGC
CGGTTCCTATTTCAGGTAGGTCTTTGTTGTGGGTGGCTTTGCAGCCTTATTTGGGGCAGGGCACGACGTCGAGTCGCTCA
GCTCCATCAGTACGTTTGATCAGTGCTGGGCATCAGCCCTTATTGCTCAAGGATGCTCGCGGTGATGTGCAGCGGGCTCC
AGTCATCACAATCACCTGGCGGTTGGTAGCTCTCGAGGAGCCCCTGCAGTTGTCACGTCAGGTGGCTGGTCCATTCGCCA
GTTTCGAGTCGGCCGAGCAGGTTGCATCGCAGTGGCGAGAGCTGGGCGTTGCGGCCGTGGTGGCTCATCCAAGCGAATGG
GAAGTGTGGGCACCGCAAGGGGTACAACCTCTCCCAGGAGTGGACATTCGTCTTTGGCAGGGCATCGTTTCTACAGCTGT
GCAGCCTGTGATTCAGGGGGACAGTGGTGATCGCAGCTTGGTGGGTCCGATTCAGATTGATGCTCCGGATGGCCTCAGTT
GGAAGGGTGGGGTGTATTTGGGGCCGTTTCAACTGCAGGTTGATGCCTACGGAAGCTGGACTTTGGTGGAACATGTTCCC
CTGGAGAGGTATCTGGAAGGAGTGGTGCCCCATGAGATTGGAGCGGGCGCTCCATCAGCAGCCTTAGCTGCTCAGACGGT
GTTGGCTAGGACCTGGGCACTTGCCAATAGCCATCGGTTTGCCCTTGATGGATACCATCTGTGCAGTGACACTCAGTGCC
AGGTTTACAGCGATCCAAGGCAGGCCAGTTTTGGTGTCCGCCAGGCGATTGCGAGCACTGCTGGCAAGGTGTTGAGCTGG
AAGGAGCAACCGATCAATGCTGTTTATCACGCCAGCAATGGTGGTGTGATGGCCGCTGGTTCTGAAGCTTGGTCCATGGA
GTCTGTTCCATACCTAAGGGCTCAGTTGGATGGATCCGTTGGATGGGTAGATCGCTTCCTTTTGCCACTCACAGAACGAG
TTGTCGTGAAGTCATTGCTGGATAATGCCGATGGTGCTTATGGCCAGGGTCATCCCCGTTTTCGTTGGACCCGTACTTTG
ACTGCTGAACAGTTGCAACAAGCTTTGCGTTTGGTGGCGCCTAGCTTGTCAATGCCCCAGCGATTGACTGTTCTTGAACG
GGGTCCAAGTGGTCGGGTCTTGTCTTTGGAGATACGTGATGAAGGCCATCAGTCCCCTGTGGTGCTTCGATTAGACGGTA
TTCGGCGTCATTTGCGTCAGTTACCAAGCACTCTCTTCGTGGTTGAGGAAGTTGGTGTCGGAGTTTGGCAGCTTTCTGGC
GGTGGTTTTGGCCATGGGGCTGGGCTTTCACAAGCCGGAGCAGTTGATCTGGCCCGTCGAGGCTGGACAACTGAACAGAT
TCTTAGTCATTACTACCCAGGAACGACCTATGGACCTTTGCCTGAGATGAAGGATGCCCCTTAG

Upstream 100 bases:

>100_bases
TTTAGGCATCTCTGACGGTCTGCGCACAAGCGACAATCTTACGATCAAGACCTGCCAGAAGCCAAATTCCGCATGATGGG
TGTTTGCCGAGGGGGCAGCA

Downstream 100 bases:

>100_bases
AGTCGCTGGACTTCGGGTCTATGCATGGCCGCCGCCGCTGTCATTGGGGATCATCGACGCGGCAAGACAGCCCTGTTTTT
GATTGCTTGCGGTTGGGCTG

Product: amidase enhancer

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP76; CWBP76; Modifier protein of major autolysin [H]

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MAKTFHRSLIRSKQVMSGALVLLGVCTVGCEAQEVIPPVGSVGMPTHQAVQAPPVPISGRSLLWVALQPYLGQGTTSSRS
APSVRLISAGHQPLLLKDARGDVQRAPVITITWRLVALEEPLQLSRQVAGPFASFESAEQVASQWRELGVAAVVAHPSEW
EVWAPQGVQPLPGVDIRLWQGIVSTAVQPVIQGDSGDRSLVGPIQIDAPDGLSWKGGVYLGPFQLQVDAYGSWTLVEHVP
LERYLEGVVPHEIGAGAPSAALAAQTVLARTWALANSHRFALDGYHLCSDTQCQVYSDPRQASFGVRQAIASTAGKVLSW
KEQPINAVYHASNGGVMAAGSEAWSMESVPYLRAQLDGSVGWVDRFLLPLTERVVVKSLLDNADGAYGQGHPRFRWTRTL
TAEQLQQALRLVAPSLSMPQRLTVLERGPSGRVLSLEIRDEGHQSPVVLRLDGIRRHLRQLPSTLFVVEEVGVGVWQLSG
GGFGHGAGLSQAGAVDLARRGWTTEQILSHYYPGTTYGPLPEMKDAP

Sequences:

>Translated_527_residues
MAKTFHRSLIRSKQVMSGALVLLGVCTVGCEAQEVIPPVGSVGMPTHQAVQAPPVPISGRSLLWVALQPYLGQGTTSSRS
APSVRLISAGHQPLLLKDARGDVQRAPVITITWRLVALEEPLQLSRQVAGPFASFESAEQVASQWRELGVAAVVAHPSEW
EVWAPQGVQPLPGVDIRLWQGIVSTAVQPVIQGDSGDRSLVGPIQIDAPDGLSWKGGVYLGPFQLQVDAYGSWTLVEHVP
LERYLEGVVPHEIGAGAPSAALAAQTVLARTWALANSHRFALDGYHLCSDTQCQVYSDPRQASFGVRQAIASTAGKVLSW
KEQPINAVYHASNGGVMAAGSEAWSMESVPYLRAQLDGSVGWVDRFLLPLTERVVVKSLLDNADGAYGQGHPRFRWTRTL
TAEQLQQALRLVAPSLSMPQRLTVLERGPSGRVLSLEIRDEGHQSPVVLRLDGIRRHLRQLPSTLFVVEEVGVGVWQLSG
GGFGHGAGLSQAGAVDLARRGWTTEQILSHYYPGTTYGPLPEMKDAP
>Mature_526_residues
AKTFHRSLIRSKQVMSGALVLLGVCTVGCEAQEVIPPVGSVGMPTHQAVQAPPVPISGRSLLWVALQPYLGQGTTSSRSA
PSVRLISAGHQPLLLKDARGDVQRAPVITITWRLVALEEPLQLSRQVAGPFASFESAEQVASQWRELGVAAVVAHPSEWE
VWAPQGVQPLPGVDIRLWQGIVSTAVQPVIQGDSGDRSLVGPIQIDAPDGLSWKGGVYLGPFQLQVDAYGSWTLVEHVPL
ERYLEGVVPHEIGAGAPSAALAAQTVLARTWALANSHRFALDGYHLCSDTQCQVYSDPRQASFGVRQAIASTAGKVLSWK
EQPINAVYHASNGGVMAAGSEAWSMESVPYLRAQLDGSVGWVDRFLLPLTERVVVKSLLDNADGAYGQGHPRFRWTRTLT
AEQLQQALRLVAPSLSMPQRLTVLERGPSGRVLSLEIRDEGHQSPVVLRLDGIRRHLRQLPSTLFVVEEVGVGVWQLSGG
GFGHGAGLSQAGAVDLARRGWTTEQILSHYYPGTTYGPLPEMKDAP

Specific function: Possibly involved in cell wall metabolism during spore formation. Enhances the amidase activity approximately threefold [H]

COG id: COG2385

COG function: function code D; Sporulation protein and related proteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein. Secreted, cell wall. Note=Cell wall localization shown in PubMed:11987133 [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007253
- InterPro:   IPR013486
- InterPro:   IPR013693 [H]

Pfam domain/function: PF04122 CW_binding_2; PF08486 SpoIID [H]

EC number: NA

Molecular weight: Translated: 56762; Mature: 56631

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTFHRSLIRSKQVMSGALVLLGVCTVGCEAQEVIPPVGSVGMPTHQAVQAPPVPISGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHCCCCCCCCCCC
SLLWVALQPYLGQGTTSSRSAPSVRLISAGHQPLLLKDARGDVQRAPVITITWRLVALEE
CEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCHHCCEEEEEEEEEEECC
PLQLSRQVAGPFASFESAEQVASQWRELGVAAVVAHPSEWEVWAPQGVQPLPGVDIRLWQ
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEECCCCCCCCCCCCHHHHH
GIVSTAVQPVIQGDSGDRSLVGPIQIDAPDGLSWKGGVYLGPFQLQVDAYGSWTLVEHVP
HHHHHHHHHHCCCCCCCCEEECCEEEECCCCCCCCCCEEECCEEEEEECCCCEEEEECCC
LERYLEGVVPHEIGAGAPSAALAAQTVLARTWALANSHRFALDGYHLCSDTQCQVYSDPR
HHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCEEECCCCCEEEECCCH
QASFGVRQAIASTAGKVLSWKEQPINAVYHASNGGVMAAGSEAWSMESVPYLRAQLDGSV
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCHHHHHCCCCH
GWVDRFLLPLTERVVVKSLLDNADGAYGQGHPRFRWTRTLTAEQLQQALRLVAPSLSMPQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCC
RLTVLERGPSGRVLSLEIRDEGHQSPVVLRLDGIRRHLRQLPSTLFVVEEVGVGVWQLSG
EEEEEECCCCCCEEEEEECCCCCCCCEEEEEHHHHHHHHHCCHHEEEHHHCCCCEEEECC
GGFGHGAGLSQAGAVDLARRGWTTEQILSHYYPGTTYGPLPEMKDAP
CCCCCCCCCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKTFHRSLIRSKQVMSGALVLLGVCTVGCEAQEVIPPVGSVGMPTHQAVQAPPVPISGR
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHCCCCCCCCCCC
SLLWVALQPYLGQGTTSSRSAPSVRLISAGHQPLLLKDARGDVQRAPVITITWRLVALEE
CEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCHHCCEEEEEEEEEEECC
PLQLSRQVAGPFASFESAEQVASQWRELGVAAVVAHPSEWEVWAPQGVQPLPGVDIRLWQ
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEECCCCCCCCCCCCHHHHH
GIVSTAVQPVIQGDSGDRSLVGPIQIDAPDGLSWKGGVYLGPFQLQVDAYGSWTLVEHVP
HHHHHHHHHHCCCCCCCCEEECCEEEECCCCCCCCCCEEECCEEEEEECCCCEEEEECCC
LERYLEGVVPHEIGAGAPSAALAAQTVLARTWALANSHRFALDGYHLCSDTQCQVYSDPR
HHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCEEECCCCCEEEECCCH
QASFGVRQAIASTAGKVLSWKEQPINAVYHASNGGVMAAGSEAWSMESVPYLRAQLDGSV
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCHHHHHCCCCH
GWVDRFLLPLTERVVVKSLLDNADGAYGQGHPRFRWTRTLTAEQLQQALRLVAPSLSMPQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCC
RLTVLERGPSGRVLSLEIRDEGHQSPVVLRLDGIRRHLRQLPSTLFVVEEVGVGVWQLSG
EEEEEECCCCCCEEEEEECCCCCCCCEEEEEHHHHHHHHHCCHHEEEHHHCCCCEEEECC
GGFGHGAGLSQAGAVDLARRGWTTEQILSHYYPGTTYGPLPEMKDAP
CCCCCCCCCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1357079; 1356138; 9384377 [H]