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The map label for this gene is cbiD

Identifier: 124021759

GI number: 124021759

Start: 43673

End: 44833

Strand: Direct

Name: cbiD

Synonym: P9303_00441

Alternate gene names: 124021759

Gene position: 43673-44833 (Clockwise)

Preceding gene: 124021757

Following gene: 124021760

Centisome position: 1.63

GC content: 55.12

Gene sequence:

>1161_bases
TTGACTCTCCCGGTTTGGGTCGCGGCTGCGGCCCGAGCTGCTACCGAAGCTTTGCTTGGAAGGCCTTTCAGTGCTTTTCA
GTTGCTTGAATTGCCTGATCGCGACGAACCTTTTGCTGTGTCAGTCACCTCTGCAGCGGTTTTGGCTGGAGGTGAACAGG
CTTTGTCAATCAGCCATTGCGATCCAGGTCCAGGTCTGGATCTCACAAGAGGTTTGGAGATTTGGGTGTGTGTTCAGTGG
CAGGAGTTGGTTGTTGGTGTTGATGATGAGTTGAATGTTCATTCAGAGGCCTGGCTGAATCTCGTGGCAGGCAAGGGTGT
TGGCACGCTGGGGTCCGGTGGAGAGGCGTGTGTGTCTCGATTTGCACGCGAGCTTTTGAGTCGTAATTTGTACCCCCTGG
TGCCTTCGGGTCGAGGGCTGCGGTTGGAAGTTGTGCTGCCTAGGGGTAGAGATTTGGCAGCACGTACCAGTAATGCAGCT
TTTGGGGTTGTGGATGGCTTGGCCTTGATTGGTACCCAGGCGGATGTGCAGGTCAGCGCCTCTCCTGATCAGTTGCAGCA
GACCATTGAGCAACTACGTCGGCAAAGTGCCGCTTCAGATTTTTGTGGAGCAATGACTTTGGTGATTGGTGAGAATGGTC
TTGATCTAGCTCGACAGTTGGGGTTGGCTGTTCAGCCGCTCCTCAAGATTGGCAATTGGTTGGGGCCTGTCATCGTGGCC
GCGGCAGAGGCTGGGGTGGAGCAATTGTTGTTGTTGGGCTATCACGGCAAGTTGGTGAAGTTGGCAGGGGGGATTTTTCA
TACTCATCACCATCTGGCAGATGGTCGTTTGGAGGTGCTTGCGGCGATGGCTGTGCGTGAAGGATTGCCGTTGGATCTGA
TCCGGCAACTTGGCCAGGCTGATTCCATGGAGGCAGCATTGAAGATGCTGGAAGCTCAAGATCCAGAGCTGGTACGCAAG
CTTTGGTATCGGCTGGCGGCAACAGTGGAGCATCGCAGCGCTGCCTACCTTGCTCGTTATGGCTCATGGTCGATCGCTAT
TGGGGCAGCTCTTTTCGATCGTCAGCGACGGTTGCGCTGGGCTGGTCCCCAAGGGTCTCAACAGTTGGCTGTCTTGGGAG
TGACCCCTGAGGATTCACCGATAAGCCTTTCTCTACCCTGA

Upstream 100 bases:

>100_bases
TGAGTTTGTCCTGCACGGCCTAAGGCTTAGTAATGAACCAACCTAGAAAATACCTAAGCAAGGGTTTTTTATCGATCACG
CCGATGCTGATTCAAGGGGG

Downstream 100 bases:

>100_bases
ACGTTCTGTTGGTTGACTCCAGAGGAGCTTTTTCGCTGATATGTCCAATTCCCAGTCTGAAGGTCAGCGCCAGCCGGCAA
TCGTCATTCTCGATTTTGGC

Product: cobalt-precorrin-6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTLPVWVAAAARAATEALLGRPFSAFQLLELPDRDEPFAVSVTSAAVLAGGEQALSISHCDPGPGLDLTRGLEIWVCVQW
QELVVGVDDELNVHSEAWLNLVAGKGVGTLGSGGEACVSRFARELLSRNLYPLVPSGRGLRLEVVLPRGRDLAARTSNAA
FGVVDGLALIGTQADVQVSASPDQLQQTIEQLRRQSAASDFCGAMTLVIGENGLDLARQLGLAVQPLLKIGNWLGPVIVA
AAEAGVEQLLLLGYHGKLVKLAGGIFHTHHHLADGRLEVLAAMAVREGLPLDLIRQLGQADSMEAALKMLEAQDPELVRK
LWYRLAATVEHRSAAYLARYGSWSIAIGAALFDRQRRLRWAGPQGSQQLAVLGVTPEDSPISLSLP

Sequences:

>Translated_386_residues
MTLPVWVAAAARAATEALLGRPFSAFQLLELPDRDEPFAVSVTSAAVLAGGEQALSISHCDPGPGLDLTRGLEIWVCVQW
QELVVGVDDELNVHSEAWLNLVAGKGVGTLGSGGEACVSRFARELLSRNLYPLVPSGRGLRLEVVLPRGRDLAARTSNAA
FGVVDGLALIGTQADVQVSASPDQLQQTIEQLRRQSAASDFCGAMTLVIGENGLDLARQLGLAVQPLLKIGNWLGPVIVA
AAEAGVEQLLLLGYHGKLVKLAGGIFHTHHHLADGRLEVLAAMAVREGLPLDLIRQLGQADSMEAALKMLEAQDPELVRK
LWYRLAATVEHRSAAYLARYGSWSIAIGAALFDRQRRLRWAGPQGSQQLAVLGVTPEDSPISLSLP
>Mature_385_residues
TLPVWVAAAARAATEALLGRPFSAFQLLELPDRDEPFAVSVTSAAVLAGGEQALSISHCDPGPGLDLTRGLEIWVCVQWQ
ELVVGVDDELNVHSEAWLNLVAGKGVGTLGSGGEACVSRFARELLSRNLYPLVPSGRGLRLEVVLPRGRDLAARTSNAAF
GVVDGLALIGTQADVQVSASPDQLQQTIEQLRRQSAASDFCGAMTLVIGENGLDLARQLGLAVQPLLKIGNWLGPVIVAA
AEAGVEQLLLLGYHGKLVKLAGGIFHTHHHLADGRLEVLAAMAVREGLPLDLIRQLGQADSMEAALKMLEAQDPELVRKL
WYRLAATVEHRSAAYLARYGSWSIAIGAALFDRQRRLRWAGPQGSQQLAVLGVTPEDSPISLSLP

Specific function: May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A

COG id: COG1903

COG function: function code H; Cobalamin biosynthesis protein CbiD

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBID_PROM3 (A2C5P1)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016066.1
- ProteinModelPortal:   A2C5P1
- STRING:   A2C5P1
- GeneID:   4778423
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_00441
- eggNOG:   COG1903
- HOGENOM:   HBG285971
- OMA:   THHHLAD
- ProtClustDB:   PRK00075
- HAMAP:   MF_00787
- InterPro:   IPR002748
- PIRSF:   PIRSF026782
- TIGRFAMs:   TIGR00312

Pfam domain/function: PF01888 CbiD; SSF111342 Cbl_biosynth_CbiD

EC number: NA

Molecular weight: Translated: 41145; Mature: 41014

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPVWVAAAARAATEALLGRPFSAFQLLELPDRDEPFAVSVTSAAVLAGGEQALSISHC
CCCCHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCCCEEEEEEHHHHEECCCCEEEEECC
DPGPGLDLTRGLEIWVCVQWQELVVGVDDELNVHSEAWLNLVAGKGVGTLGSGGEACVSR
CCCCCCCCCCCCEEEEEEEEEHEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHH
FARELLSRNLYPLVPSGRGLRLEVVLPRGRDLAARTSNAAFGVVDGLALIGTQADVQVSA
HHHHHHHCCCCEECCCCCCEEEEEEECCCCCCHHCCCCCCHHHHHHHHHCCCCCCEEEEC
SPDQLQQTIEQLRRQSAASDFCGAMTLVIGENGLDLARQLGLAVQPLLKIGNWLGPVIVA
CHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHHHHH
AAEAGVEQLLLLGYHGKLVKLAGGIFHTHHHLADGRLEVLAAMAVREGLPLDLIRQLGQA
HHHHCHHHHHHHCCCCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHCCC
DSMEAALKMLEAQDPELVRKLWYRLAATVEHRSAAYLARYGSWSIAIGAALFDRQRRLRW
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHEE
AGPQGSQQLAVLGVTPEDSPISLSLP
CCCCCCCEEEEEEECCCCCCEEEECC
>Mature Secondary Structure 
TLPVWVAAAARAATEALLGRPFSAFQLLELPDRDEPFAVSVTSAAVLAGGEQALSISHC
CCCHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCCCEEEEEEHHHHEECCCCEEEEECC
DPGPGLDLTRGLEIWVCVQWQELVVGVDDELNVHSEAWLNLVAGKGVGTLGSGGEACVSR
CCCCCCCCCCCCEEEEEEEEEHEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHH
FARELLSRNLYPLVPSGRGLRLEVVLPRGRDLAARTSNAAFGVVDGLALIGTQADVQVSA
HHHHHHHCCCCEECCCCCCEEEEEEECCCCCCHHCCCCCCHHHHHHHHHCCCCCCEEEEC
SPDQLQQTIEQLRRQSAASDFCGAMTLVIGENGLDLARQLGLAVQPLLKIGNWLGPVIVA
CHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHHHHH
AAEAGVEQLLLLGYHGKLVKLAGGIFHTHHHLADGRLEVLAAMAVREGLPLDLIRQLGQA
HHHHCHHHHHHHCCCCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHCCC
DSMEAALKMLEAQDPELVRKLWYRLAATVEHRSAAYLARYGSWSIAIGAALFDRQRRLRW
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHEE
AGPQGSQQLAVLGVTPEDSPISLSLP
CCCCCCCEEEEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA