Click here to switch to the map view.

The map label for this gene is dhsS

Identifier: 124021758

GI number: 124021758

Start: 42440

End: 43588

Strand: Reverse

Name: dhsS

Synonym: P9303_00431

Alternate gene names: NA

Gene position: 43588-42440 (Counterclockwise)

Preceding gene: 124021765

Following gene: 124021754

Centisome position: 1.62

GC content: 53.35

Gene sequence:

>1149_bases
GTGCAGGACAAACTCACCCTGATGATCCCGGGTCCTACACCGGTTCCCGAAACAGTACTCAAAGCAATGGGTCGCCACCC
CATCGGCCATCGCAGTGGAGAGTTTCAAGCCGTCGTTAGACATACCACCGAGCAGCTGCGCTGGCTGCATCAGACCAAAT
CAGATGTTCTAGTCATCACTGGCAGCGGCACCGCTGCGATGGAAGCAGGAATCATCAATACCCTCAGCTACGGCGACAAG
GTTCTCTGCGGCGACAACGGCAAGTTTGGACAGCGCTGGGTAAAGCTGGCTAAGGCTTACGGCCTGGACGTACAAGTGAT
AAAAGCAGACTGGGGACAACCGTTAGACCCAGAAGCCTTCAAAAGAGCACTGGAAGCAGACAATGGCAAAACAATCAAAG
CGGTAATTCTTACCCACTCGGAAACCTCAACCGGGGTCATTAACGACCTTGAAACCATCAGCAAATATGTCCGCACTCAC
GGCAAAGCACTAACCATCGCTGATTGCGTGACAAGCCTTGGGGCCTGCAATGTACCCATGGATTCTTGGGGTCTAGATGT
GGTTGCCTCCGGTTCCCAAAAGGGATACATGATGCCTCCAGGTCTCAGCTTCGTGGCCATGAGTGAACGAGCCTGGCAAG
CACATCAACAATCGGATCTACCGAAGTTTTATCTCGATCTGGGGCCTTACCGAAAAACTGCCGCTCAAGACAGCAATCCA
TTCACCCCTGCTGTGAATCTCTACTTCGCACTGGAATCTGCGCTGGGAATGATGCAGTCAGAAGGACTAGAAGCCATCTT
TGACCGTCATGCCCGCCACCGCGCAGCCGCTCAGGCCGGCATGAAGGCCATCTGCCTGCCCCTGTATGCAGCTGAAGGAC
ACGGCAGCCCAGCGATCACCGCAGTCGCACCTGAGGGAGTTGATGCAGAGCAACTGCGCAAAACTGTCAAAGAGAAATTC
GACATCCTGCTAGCAGGTGGACAGGATCATCTAAAAGGGAAGGTCTTCCGTATCGGCCATCTTGGATTCGTATGTGATAG
AGATATCCTCACTGCCATAGCTGCCATCGAATCCACCTTGCAATCTCTTGGCTTGCATAAAGGCAACATGGGAGATGGCC
TGGCTGCTGCTGCAGCAATTCTGAGATAA

Upstream 100 bases:

>100_bases
AAACCGGGAGAGTCAACCCCCTTGAATCAGCATCGGCGTGATCGATAAAAAACCCTTGCTTAGGTATTTTCTAGGTTGGT
TCATTACTAAGCCTTAGGCC

Downstream 100 bases:

>100_bases
CAGTGCTCGCCAACAAAACGAACTAAAGCTGATCTAAACTGATAAAATGCGGGTGTAATTCAGTGGTAGAATGTCAGCTT
CCCAAGCTGAACGTCGCCGG

Product: soluble hydrogenase small subunit

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQDKLTLMIPGPTPVPETVLKAMGRHPIGHRSGEFQAVVRHTTEQLRWLHQTKSDVLVITGSGTAAMEAGIINTLSYGDK
VLCGDNGKFGQRWVKLAKAYGLDVQVIKADWGQPLDPEAFKRALEADNGKTIKAVILTHSETSTGVINDLETISKYVRTH
GKALTIADCVTSLGACNVPMDSWGLDVVASGSQKGYMMPPGLSFVAMSERAWQAHQQSDLPKFYLDLGPYRKTAAQDSNP
FTPAVNLYFALESALGMMQSEGLEAIFDRHARHRAAAQAGMKAICLPLYAAEGHGSPAITAVAPEGVDAEQLRKTVKEKF
DILLAGGQDHLKGKVFRIGHLGFVCDRDILTAIAAIESTLQSLGLHKGNMGDGLAAAAAILR

Sequences:

>Translated_382_residues
MQDKLTLMIPGPTPVPETVLKAMGRHPIGHRSGEFQAVVRHTTEQLRWLHQTKSDVLVITGSGTAAMEAGIINTLSYGDK
VLCGDNGKFGQRWVKLAKAYGLDVQVIKADWGQPLDPEAFKRALEADNGKTIKAVILTHSETSTGVINDLETISKYVRTH
GKALTIADCVTSLGACNVPMDSWGLDVVASGSQKGYMMPPGLSFVAMSERAWQAHQQSDLPKFYLDLGPYRKTAAQDSNP
FTPAVNLYFALESALGMMQSEGLEAIFDRHARHRAAAQAGMKAICLPLYAAEGHGSPAITAVAPEGVDAEQLRKTVKEKF
DILLAGGQDHLKGKVFRIGHLGFVCDRDILTAIAAIESTLQSLGLHKGNMGDGLAAAAAILR
>Mature_382_residues
MQDKLTLMIPGPTPVPETVLKAMGRHPIGHRSGEFQAVVRHTTEQLRWLHQTKSDVLVITGSGTAAMEAGIINTLSYGDK
VLCGDNGKFGQRWVKLAKAYGLDVQVIKADWGQPLDPEAFKRALEADNGKTIKAVILTHSETSTGVINDLETISKYVRTH
GKALTIADCVTSLGACNVPMDSWGLDVVASGSQKGYMMPPGLSFVAMSERAWQAHQQSDLPKFYLDLGPYRKTAAQDSNP
FTPAVNLYFALESALGMMQSEGLEAIFDRHARHRAAAQAGMKAICLPLYAAEGHGSPAITAVAPEGVDAEQLRKTVKEKF
DILLAGGQDHLKGKVFRIGHLGFVCDRDILTAIAAIESTLQSLGLHKGNMGDGLAAAAAILR

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=366, Percent_Identity=31.6939890710383, Blast_Score=155, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17536281, Length=347, Percent_Identity=31.1239193083574, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6321079, Length=370, Percent_Identity=27.027027027027, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17530823, Length=347, Percent_Identity=29.6829971181556, Blast_Score=145, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 41053; Mature: 41053

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDKLTLMIPGPTPVPETVLKAMGRHPIGHRSGEFQAVVRHTTEQLRWLHQTKSDVLVIT
CCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
GSGTAAMEAGIINTLSYGDKVLCGDNGKFGQRWVKLAKAYGLDVQVIKADWGQPLDPEAF
CCCCHHHHHCHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHH
KRALEADNGKTIKAVILTHSETSTGVINDLETISKYVRTHGKALTIADCVTSLGACNVPM
HHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCCC
DSWGLDVVASGSQKGYMMPPGLSFVAMSERAWQAHQQSDLPKFYLDLGPYRKTAAQDSNP
CCCCCEEEECCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCCEECCCCCCHHHHCCCCCC
FTPAVNLYFALESALGMMQSEGLEAIFDRHARHRAAAQAGMKAICLPLYAAEGHGSPAIT
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEE
AVAPEGVDAEQLRKTVKEKFDILLAGGQDHLKGKVFRIGHLGFVCDRDILTAIAAIESTL
EECCCCCCHHHHHHHHHHHHCEEEECCCHHHCCEEEEEECCCCEECHHHHHHHHHHHHHH
QSLGLHKGNMGDGLAAAAAILR
HHHCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MQDKLTLMIPGPTPVPETVLKAMGRHPIGHRSGEFQAVVRHTTEQLRWLHQTKSDVLVIT
CCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
GSGTAAMEAGIINTLSYGDKVLCGDNGKFGQRWVKLAKAYGLDVQVIKADWGQPLDPEAF
CCCCHHHHHCHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHH
KRALEADNGKTIKAVILTHSETSTGVINDLETISKYVRTHGKALTIADCVTSLGACNVPM
HHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCCC
DSWGLDVVASGSQKGYMMPPGLSFVAMSERAWQAHQQSDLPKFYLDLGPYRKTAAQDSNP
CCCCCEEEECCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCCEECCCCCCHHHHCCCCCC
FTPAVNLYFALESALGMMQSEGLEAIFDRHARHRAAAQAGMKAICLPLYAAEGHGSPAIT
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEE
AVAPEGVDAEQLRKTVKEKFDILLAGGQDHLKGKVFRIGHLGFVCDRDILTAIAAIESTL
EECCCCCCHHHHHHHHHHHHCEEEECCCHHHCCEEEEEECCCCEECHHHHHHHHHHHHHH
QSLGLHKGNMGDGLAAAAAILR
HHHCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513553 [H]