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The map label for this gene is efp [H]

Identifier: 124021745

GI number: 124021745

Start: 34184

End: 34744

Strand: Direct

Name: efp [H]

Synonym: P9303_00301

Alternate gene names: 124021745

Gene position: 34184-34744 (Clockwise)

Preceding gene: 124021742

Following gene: 124021746

Centisome position: 1.27

GC content: 49.91

Gene sequence:

>561_bases
ATGATCTCAAGTAACGACTTCCGCACTGGCACCTCGATTGAATTAGACGGTTCTGTGTGGCGTGTAGTCGAGTTTTTGCA
TGTGAAACCGGGTAAGGGTTCAGCATTTGTGCGTACCAAGTTGAAGGCGGTGCAGAGCGGCAGCGTGGTGGAAAAAACCT
TTAGGGCTGGGGAGATGCTTCCGCAGGCCTTGCTTGAGAAGTCGACCCTTCAACACACGTATATGGAGTCCGGTGACTAT
GTCTTTATGGACATGTCTAGTTATGAGGAAACTAGGCTTACAGCGCAGCAGATCGGTGACAGTCGTAAATACCTCAAGGA
AGGGATGGAGGTGAATGTGGTCTCATGGAACGGAAATCCTCTTGAGGTGGAGCTCCCCAATTCTGTGGTGCTTGAAATCA
CTGAAACTGATCCTGGTGTCAAGGGTGATACCGCTACCGGTGGTACTAAGCCCGCCATCCTTGAGACTGGTGCTCAGGTG
ATGGTTCCTTTGTTTCTTTCTGTGGGCGAGAAAATTAAAGTCGATACACGTAACGACAGCTACCTAGGTCGCGAGAACTA
A

Upstream 100 bases:

>100_bases
GTGACCAGGCTGGTCAGTAGAGGAGTATTTGGCATGTGGAACTCTTCTTGTGCTGGGACTTTGGCACAGCCGTATGATCC
CTCTGATCCGTTCAGCGGGA

Downstream 100 bases:

>100_bases
TGGCTATGCAGCTCGATCATGATCAACTGCACCAGTTGCTTGCAGCCTTGGCGGAAAGCGACATCCAGGAATTTCGCCTT
GAGGGCGATGATTTTCGTCT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MISSNDFRTGTSIELDGSVWRVVEFLHVKPGKGSAFVRTKLKAVQSGSVVEKTFRAGEMLPQALLEKSTLQHTYMESGDY
VFMDMSSYEETRLTAQQIGDSRKYLKEGMEVNVVSWNGNPLEVELPNSVVLEITETDPGVKGDTATGGTKPAILETGAQV
MVPLFLSVGEKIKVDTRNDSYLGREN

Sequences:

>Translated_186_residues
MISSNDFRTGTSIELDGSVWRVVEFLHVKPGKGSAFVRTKLKAVQSGSVVEKTFRAGEMLPQALLEKSTLQHTYMESGDY
VFMDMSSYEETRLTAQQIGDSRKYLKEGMEVNVVSWNGNPLEVELPNSVVLEITETDPGVKGDTATGGTKPAILETGAQV
MVPLFLSVGEKIKVDTRNDSYLGREN
>Mature_186_residues
MISSNDFRTGTSIELDGSVWRVVEFLHVKPGKGSAFVRTKLKAVQSGSVVEKTFRAGEMLPQALLEKSTLQHTYMESGDY
VFMDMSSYEETRLTAQQIGDSRKYLKEGMEVNVVSWNGNPLEVELPNSVVLEITETDPGVKGDTATGGTKPAILETGAQV
MVPLFLSVGEKIKVDTRNDSYLGREN

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=181, Percent_Identity=46.9613259668508, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI87082061, Length=190, Percent_Identity=32.1052631578947, Blast_Score=109, Evalue=1e-25,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20468; Mature: 20468

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSNDFRTGTSIELDGSVWRVVEFLHVKPGKGSAFVRTKLKAVQSGSVVEKTFRAGEML
CCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
PQALLEKSTLQHTYMESGDYVFMDMSSYEETRLTAQQIGDSRKYLKEGMEVNVVSWNGNP
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHCCCEEEEEEECCCE
LEVELPNSVVLEITETDPGVKGDTATGGTKPAILETGAQVMVPLFLSVGEKIKVDTRNDS
EEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCEEEEECCCCC
YLGREN
CCCCCC
>Mature Secondary Structure
MISSNDFRTGTSIELDGSVWRVVEFLHVKPGKGSAFVRTKLKAVQSGSVVEKTFRAGEML
CCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
PQALLEKSTLQHTYMESGDYVFMDMSSYEETRLTAQQIGDSRKYLKEGMEVNVVSWNGNP
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHCCCEEEEEEECCCE
LEVELPNSVVLEITETDPGVKGDTATGGTKPAILETGAQVMVPLFLSVGEKIKVDTRNDS
EEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCEEEEECCCCC
YLGREN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA