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The map label for this gene is glmS [H]

Identifier: 123969348

GI number: 123969348

Start: 1548284

End: 1550179

Strand: Reverse

Name: glmS [H]

Synonym: A9601_18161

Alternate gene names: 123969348

Gene position: 1550179-1548284 (Counterclockwise)

Preceding gene: 123969349

Following gene: 123969346

Centisome position: 92.83

GC content: 32.49

Gene sequence:

>1896_bases
ATGTGTGGAATAGTTGCTGTAACTGGATATAAAAAAGCTCTTCCATTATTAATAAATGGTTTAGAAAAACTCGAATACAG
AGGTTACGATTCTGCAGGTATTGCGATAATAAATACCGAAACAAATTGTATTTCTTGTAATAAAGCAGAAGGAAAACTAA
AGAATTTAATAAATAATCTTAATAATCACAATATTCCTGGAACTGTGGGTATAGGTCATACCAGATGGGCAACTCATGGA
AAGCCTGAGGTTAAAAATGCTCATCCTCATACCGATAGTTCTGGGAACATAGCAGTTGTACAAAATGGCATTATTGAAAA
TTTTCAAGATTTAAAGAATAAATTAGAGGAAGAGGGCATTAGTTTTAATTCTGATACAGATACCGAGGTAATTCCTCATC
TAATTCAAAGAGAGTTAAATACATTAGGTAAACTTAAACTTGAGAATAATGGTTCGACATTATTAATAGCTGTGAGAAAT
GTAATATCTGATTTAGAAGGATCTTATGCTTTAGCAGTTTTATGGTCTGGAGCCCCAACATCTTTGGTAGTTGCAAGAAA
ACAAGCGCCCTTGATTATTGGTTTGGGTGAAGGAGAATTTATTTGTGCTAGTGATACTCCAGCTATTGCAAACTTTACGA
ATATTATTTTGCCTATGGAGGATGAAGAAATAGCTTTATTAACTCCGCTTGGAATTGAAATATATGACTCAAGTAACGAG
AGACAATATCGAAATCCAGTTTCTCTAAAAGTCTCTGAGCAAATAATGGATAAGATGAACTTCAAACACTACATGTTAAA
AGAAATATATGATCAGCCAAAGACTGCAAAAAACTGGTTAGAGAATTATTTAATTAAGAACTTAGATAATGGTCAATATC
AAATCAAGTATCCTTTTGATACAAAGTTTTTCGAATCAATAGAAAGAATTGAAATTATTGCTTGTGGTACAAGTAAACAT
GCTGCAATGGTAGGTAGCTTTTTATTAGAACAATTTTCAGGTATCCCTACAAATGTCTTTTATGCAAGCGAATTTCGATA
TTCTCCACCTCCATTATTACCAAATACATTAACTATTGGAGTCACTCAATCTGGAGAAACTGCTGATACCATCGCGGCTA
TCGACATGGAAATTAAAAGACGTTCTTCAATTGAAGATAAAAAATTTAAACCTAACCTTATTGCAATAACAAATAGAAAA
GAGAGTTCCATAGGAAGGCAGGTTTCTAATATAATTGATATCTGTGCAGGAATAGAAGTTGGAGTAGCTGCAACAAAAAC
TTTTTTTGCTCAATTACTTTCTTTTTATGGATTAGCCATAAAATTTGCTCAAATTAAAGGCAACCAAAGTCCTGATGAAA
TAGGAAAATTAATAAACGAACTGATAAAACTTCCTCCATTACTGGAAGATCTCTTAGAGAAGCATAATAAATCTTCAGAA
AAACTAGCACATGACTTTTTTAATATTAAAGATGTTATTTTTTTAGGGAGAGGAATAAATTATCCAATTGCTCTTGAAGG
TGCGTTAAAACTTAAAGAAATTAGTTATATTCATGCTGCTGGATATCCTGCTGGTGAAATGAAACATGGTCCAATAGCTT
TATTAGATAAAAAAGTACCTGTAATTTCAATTGCCTCTCCCGGTGAAGTTTTTGATAAAGTTATTAGTAATGCACAAGAA
GCGAAAGCTAGAGATTCATATTTGATTGGGATAGCTCCTGAATGTAATGGAACTGAAATCTTTGATTATTTAATGAAAGT
TCCCTCCACTAATGAATGGATTTCACCTCTACTTAATATATTGCCTTTACAATTATTGAGTTACCATATCGCAGCTCATA
GAGGCCTTGATGTGGATCAACCAAGAAATTTAGCTAAAAGTGTAACTGTGGAATAA

Upstream 100 bases:

>100_bases
GTATGGGCTTAGCATATTAATTTTTATAGTGCAGTTTTAAGAGAGTCCATTTTTTATTAAATACGCATTTTATTTCAATA
TAATTGAAAAAAAGTTTCGT

Downstream 100 bases:

>100_bases
TTATTTTCTTAAAAATTTGTATTTTAAATTTATAGTTCTAAAAGTCCATTTGGAGGATTGATGATTAAAAAATTATTTTT
AATATCTACTAATGGGACTA

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MCGIVAVTGYKKALPLLINGLEKLEYRGYDSAGIAIINTETNCISCNKAEGKLKNLINNLNNHNIPGTVGIGHTRWATHG
KPEVKNAHPHTDSSGNIAVVQNGIIENFQDLKNKLEEEGISFNSDTDTEVIPHLIQRELNTLGKLKLENNGSTLLIAVRN
VISDLEGSYALAVLWSGAPTSLVVARKQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDSSNE
RQYRNPVSLKVSEQIMDKMNFKHYMLKEIYDQPKTAKNWLENYLIKNLDNGQYQIKYPFDTKFFESIERIEIIACGTSKH
AAMVGSFLLEQFSGIPTNVFYASEFRYSPPPLLPNTLTIGVTQSGETADTIAAIDMEIKRRSSIEDKKFKPNLIAITNRK
ESSIGRQVSNIIDICAGIEVGVAATKTFFAQLLSFYGLAIKFAQIKGNQSPDEIGKLINELIKLPPLLEDLLEKHNKSSE
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVPVISIASPGEVFDKVISNAQE
AKARDSYLIGIAPECNGTEIFDYLMKVPSTNEWISPLLNILPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE

Sequences:

>Translated_631_residues
MCGIVAVTGYKKALPLLINGLEKLEYRGYDSAGIAIINTETNCISCNKAEGKLKNLINNLNNHNIPGTVGIGHTRWATHG
KPEVKNAHPHTDSSGNIAVVQNGIIENFQDLKNKLEEEGISFNSDTDTEVIPHLIQRELNTLGKLKLENNGSTLLIAVRN
VISDLEGSYALAVLWSGAPTSLVVARKQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDSSNE
RQYRNPVSLKVSEQIMDKMNFKHYMLKEIYDQPKTAKNWLENYLIKNLDNGQYQIKYPFDTKFFESIERIEIIACGTSKH
AAMVGSFLLEQFSGIPTNVFYASEFRYSPPPLLPNTLTIGVTQSGETADTIAAIDMEIKRRSSIEDKKFKPNLIAITNRK
ESSIGRQVSNIIDICAGIEVGVAATKTFFAQLLSFYGLAIKFAQIKGNQSPDEIGKLINELIKLPPLLEDLLEKHNKSSE
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVPVISIASPGEVFDKVISNAQE
AKARDSYLIGIAPECNGTEIFDYLMKVPSTNEWISPLLNILPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE
>Mature_631_residues
MCGIVAVTGYKKALPLLINGLEKLEYRGYDSAGIAIINTETNCISCNKAEGKLKNLINNLNNHNIPGTVGIGHTRWATHG
KPEVKNAHPHTDSSGNIAVVQNGIIENFQDLKNKLEEEGISFNSDTDTEVIPHLIQRELNTLGKLKLENNGSTLLIAVRN
VISDLEGSYALAVLWSGAPTSLVVARKQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDSSNE
RQYRNPVSLKVSEQIMDKMNFKHYMLKEIYDQPKTAKNWLENYLIKNLDNGQYQIKYPFDTKFFESIERIEIIACGTSKH
AAMVGSFLLEQFSGIPTNVFYASEFRYSPPPLLPNTLTIGVTQSGETADTIAAIDMEIKRRSSIEDKKFKPNLIAITNRK
ESSIGRQVSNIIDICAGIEVGVAATKTFFAQLLSFYGLAIKFAQIKGNQSPDEIGKLINELIKLPPLLEDLLEKHNKSSE
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVPVISIASPGEVFDKVISNAQE
AKARDSYLIGIAPECNGTEIFDYLMKVPSTNEWISPLLNILPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=702, Percent_Identity=34.045584045584, Blast_Score=345, Evalue=7e-95,
Organism=Homo sapiens, GI205277386, Length=701, Percent_Identity=32.9529243937233, Blast_Score=334, Evalue=2e-91,
Organism=Escherichia coli, GI1790167, Length=635, Percent_Identity=41.5748031496063, Blast_Score=453, Evalue=1e-128,
Organism=Escherichia coli, GI1788651, Length=219, Percent_Identity=28.7671232876712, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082251, Length=320, Percent_Identity=23.4375, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17532899, Length=449, Percent_Identity=35.4120267260579, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17532897, Length=449, Percent_Identity=35.4120267260579, Blast_Score=236, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17539970, Length=448, Percent_Identity=34.375, Blast_Score=235, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17554892, Length=250, Percent_Identity=27.6, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322745, Length=446, Percent_Identity=33.4080717488789, Blast_Score=227, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6323731, Length=458, Percent_Identity=27.9475982532751, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323730, Length=210, Percent_Identity=39.5238095238095, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6323958, Length=182, Percent_Identity=27.4725274725275, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21357745, Length=714, Percent_Identity=33.6134453781513, Blast_Score=357, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24659598, Length=203, Percent_Identity=28.0788177339901, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24659604, Length=183, Percent_Identity=28.4153005464481, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573187, Length=118, Percent_Identity=33.8983050847458, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 69643; Mature: 69643

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVAVTGYKKALPLLINGLEKLEYRGYDSAGIAIINTETNCISCNKAEGKLKNLINNL
CCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHC
NNHNIPGTVGIGHTRWATHGKPEVKNAHPHTDSSGNIAVVQNGIIENFQDLKNKLEEEGI
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCC
SFNSDTDTEVIPHLIQRELNTLGKLKLENNGSTLLIAVRNVISDLEGSYALAVLWSGAPT
CCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEHHHHHHHCCCCEEEEEEECCCCC
SLVVARKQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDSSNE
EEEEEECCCCEEEECCCCCEEEECCCCCHHCCEEEEEECCCCCEEEEECCCEEEEECCCC
RQYRNPVSLKVSEQIMDKMNFKHYMLKEIYDQPKTAKNWLENYLIKNLDNGQYQIKYPFD
CCCCCCCCEEEHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
TKFFESIERIEIIACGTSKHAAMVGSFLLEQFSGIPTNVFYASEFRYSPPPLLPNTLTIG
CHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEE
VTQSGETADTIAAIDMEIKRRSSIEDKKFKPNLIAITNRKESSIGRQVSNIIDICAGIEV
EECCCCCHHHEEEHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCC
GVAATKTFFAQLLSFYGLAIKFAQIKGNQSPDEIGKLINELIKLPPLLEDLLEKHNKSSE
CHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHH
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVP
HHHHHHHCHHEEEEECCCCCCCEEECCCEEEHHEEEEEECCCCCCCCCCCCEEEEECCCC
VISIASPGEVFDKVISNAQEAKARDSYLIGIAPECNGTEIFDYLMKVPSTNEWISPLLNI
EEEECCCHHHHHHHHCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHH
LPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MCGIVAVTGYKKALPLLINGLEKLEYRGYDSAGIAIINTETNCISCNKAEGKLKNLINNL
CCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHC
NNHNIPGTVGIGHTRWATHGKPEVKNAHPHTDSSGNIAVVQNGIIENFQDLKNKLEEEGI
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCC
SFNSDTDTEVIPHLIQRELNTLGKLKLENNGSTLLIAVRNVISDLEGSYALAVLWSGAPT
CCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEHHHHHHHCCCCEEEEEEECCCCC
SLVVARKQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDSSNE
EEEEEECCCCEEEECCCCCEEEECCCCCHHCCEEEEEECCCCCEEEEECCCEEEEECCCC
RQYRNPVSLKVSEQIMDKMNFKHYMLKEIYDQPKTAKNWLENYLIKNLDNGQYQIKYPFD
CCCCCCCCEEEHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
TKFFESIERIEIIACGTSKHAAMVGSFLLEQFSGIPTNVFYASEFRYSPPPLLPNTLTIG
CHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEE
VTQSGETADTIAAIDMEIKRRSSIEDKKFKPNLIAITNRKESSIGRQVSNIIDICAGIEV
EECCCCCHHHEEEHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCC
GVAATKTFFAQLLSFYGLAIKFAQIKGNQSPDEIGKLINELIKLPPLLEDLLEKHNKSSE
CHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHH
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVP
HHHHHHHCHHEEEEECCCCCCCEEECCCEEEHHEEEEEECCCCCCCCCCCCEEEEECCCC
VISIASPGEVFDKVISNAQEAKARDSYLIGIAPECNGTEIFDYLMKVPSTNEWISPLLNI
EEEECCCHHHHHHHHCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHH
LPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]