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The map label for this gene is rnc [H]

Identifier: 123969345

GI number: 123969345

Start: 1546751

End: 1547500

Strand: Direct

Name: rnc [H]

Synonym: A9601_18131

Alternate gene names: 123969345

Gene position: 1546751-1547500 (Clockwise)

Preceding gene: 123969342

Following gene: 123969347

Centisome position: 92.63

GC content: 28.8

Gene sequence:

>750_bases
ATGACAAATATAATTAATGCAAAGAGAATTAATCAAATAACTACTTTCTTAAAGGCTTTAAATATTAAATCGAAAAGATT
TTCTGAAATAATTAGAAATCAAGATATTTCAGTTATTCAAGATTTTAATCAAGCATTTATCCACTCCTCAGAGGACAAAA
TAATAAATTACGAAAAACTAGAATTTTTCGGAGATGCAGTGCTCAGATTAGCTGCTTCAAATTTTATTGAAAAAAAATAT
CCTCAAATGAGTGTAGGAGAAAGATCAGAGCTAAGAGCACAAATTGTAAGTGATGAATGGTTAACTAAATTAGGCGAAAA
AATTGATATAGAAAAATTAATAATTAAAGGACCTAAAGCTATTGGTGATGAAAATTCAAAAAATACTATTATTTGTGAAG
CTACAGAAGCTTTAATCGGTGCTATCTATAAGTGCTTTAGTTCAATTAAGGAAGTAAATCTTTGGTTAGATGATATTTGG
GAGGAAGATTCGGAAATATTTTTAAAATCTCCATATAAATTCAAATCTAAGACAGTATTGCAAGAGTGGTGCCAAAGTAA
AGGTTTTGATTTGCCAGTCTATAAAATAATTGAAGTCTCAAAAAAAAATGGGGACCCTGAAAGATTCTATTGCAATATAT
TTATCGAAGGATTAAAAGAGTCATCTGCATTCGGCAAATCCCATAAACAAGCAGAAACAAATGCAGCTAGAGTTTTGATA
GAAAAATTTATAGCTAAAGGTCAAATCTAA

Upstream 100 bases:

>100_bases
AAGTAATTCCAGTCCTAGATAGATGATTGCCCATCTTTATTAAGATGAACAGAACCCGGCTTATGACCTGCTTTCTAATT
GTTGTGATTATTCAAATCAG

Downstream 100 bases:

>100_bases
TTTTTATACTATTTCTAAATTCGTTAGCTGAAAAGTTATGAGTTTATCCCAATTACCCCCTTCAAACAGAACAGCTGCCC
TTTTTTTTGTAACTCTTTGT

Product: putative ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III 2; RNase III 2 [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTNIINAKRINQITTFLKALNIKSKRFSEIIRNQDISVIQDFNQAFIHSSEDKIINYEKLEFFGDAVLRLAASNFIEKKY
PQMSVGERSELRAQIVSDEWLTKLGEKIDIEKLIIKGPKAIGDENSKNTIICEATEALIGAIYKCFSSIKEVNLWLDDIW
EEDSEIFLKSPYKFKSKTVLQEWCQSKGFDLPVYKIIEVSKKNGDPERFYCNIFIEGLKESSAFGKSHKQAETNAARVLI
EKFIAKGQI

Sequences:

>Translated_249_residues
MTNIINAKRINQITTFLKALNIKSKRFSEIIRNQDISVIQDFNQAFIHSSEDKIINYEKLEFFGDAVLRLAASNFIEKKY
PQMSVGERSELRAQIVSDEWLTKLGEKIDIEKLIIKGPKAIGDENSKNTIICEATEALIGAIYKCFSSIKEVNLWLDDIW
EEDSEIFLKSPYKFKSKTVLQEWCQSKGFDLPVYKIIEVSKKNGDPERFYCNIFIEGLKESSAFGKSHKQAETNAARVLI
EKFIAKGQI
>Mature_248_residues
TNIINAKRINQITTFLKALNIKSKRFSEIIRNQDISVIQDFNQAFIHSSEDKIINYEKLEFFGDAVLRLAASNFIEKKYP
QMSVGERSELRAQIVSDEWLTKLGEKIDIEKLIIKGPKAIGDENSKNTIICEATEALIGAIYKCFSSIKEVNLWLDDIWE
EDSEIFLKSPYKFKSKTVLQEWCQSKGFDLPVYKIIEVSKKNGDPERFYCNIFIEGLKESSAFGKSHKQAETNAARVLIE
KFIAKGQI

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Escherichia coli, GI1788920, Length=188, Percent_Identity=28.7234042553192, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 28575; Mature: 28444

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS50137 DS_RBD ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNIINAKRINQITTFLKALNIKSKRFSEIIRNQDISVIQDFNQAFIHSSEDKIINYEKL
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHH
EFFGDAVLRLAASNFIEKKYPQMSVGERSELRAQIVSDEWLTKLGEKIDIEKLIIKGPKA
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHH
IGDENSKNTIICEATEALIGAIYKCFSSIKEVNLWLDDIWEEDSEIFLKSPYKFKSKTVL
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHH
QEWCQSKGFDLPVYKIIEVSKKNGDPERFYCNIFIEGLKESSAFGKSHKQAETNAARVLI
HHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EKFIAKGQI
HHHHHCCCC
>Mature Secondary Structure 
TNIINAKRINQITTFLKALNIKSKRFSEIIRNQDISVIQDFNQAFIHSSEDKIINYEKL
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHH
EFFGDAVLRLAASNFIEKKYPQMSVGERSELRAQIVSDEWLTKLGEKIDIEKLIIKGPKA
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHH
IGDENSKNTIICEATEALIGAIYKCFSSIKEVNLWLDDIWEEDSEIFLKSPYKFKSKTVL
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHH
QEWCQSKGFDLPVYKIIEVSKKNGDPERFYCNIFIEGLKESSAFGKSHKQAETNAARVLI
HHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EKFIAKGQI
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]