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The map label for this gene is rpoC1 [H]

Identifier: 123969220

GI number: 123969220

Start: 1428254

End: 1430158

Strand: Reverse

Name: rpoC1 [H]

Synonym: A9601_16881

Alternate gene names: 123969220

Gene position: 1430158-1428254 (Counterclockwise)

Preceding gene: 123969221

Following gene: 123969219

Centisome position: 85.64

GC content: 36.85

Gene sequence:

>1905_bases
ATGACAAACAGCAACTTAAGAACTGAAAATCACTTTGATTACGTCAAAATTTCAATAGCTTCTCCACAAAGAATAATGGA
TTGGGGTCAGAGGACATTGCCCAATGGACAAGTTGTTGGTGAAGTTACTAAACCTGAAACTATCAATTACAGGACACTTA
AACCAGAAATGGACGGATTGTTTTGTGAAAAGATTTTTGGGCCATCTAAAGATTGGGAATGCCATTGCGGGAAATACAAA
AGGGTAAGACATCGCGGCATCGTTTGTGAGAGATGTGGGGTTGAAGTAACTGAAAGTAGAGTAAGAAGACATAGGATGGG
TTATATAAAACTCGCTGCGCCAGTTTCCCATGTTTGGTATTTGAAAGGAATTCCTAGTTACGTTGCAATACTTTTGGATA
TTCCGCTTAGGGATGTAGAACAAATAGTTTATTTTAATTGTTATGTCGTTTTAGATCCAGGTGATCATAAAGAACTTAAA
TATAAGCAATTACTCACTGAGGATGAGTGGCTTGAAATTGAAGATGAAATTTATGCGGAAGATTCAACTATAGAGAATGA
ACCTTTTGTTGGAATTGGTGCTGAGGCACTGAAGCAATTACTAGAGGACCTTGATTTACATCAGATTGCTGAGGAGCTTA
GAGAAGAAATTACTAATAGCAAAGGGCAAAAGAGGGCAAAACTTATAAAAAGGATAAGAGTTATTGATAATTTTATTGCC
ACTAATGCAAAACCAGAATGGATGGTTTTAGATGCAATCCCAGTTATACCTCCTGATCTTAGACCTATGGTTCAGCTTGA
TGGGGGGAGATTTGCAACTTCAGATTTAAACGACTTATATAGAAGAGTTATAAATAGAAATAATAGACTAGCCAGGCTTC
AAGAAATTTTAGCTCCTGAAATCATAGTAAGAAATGAAAAAAGAATGCTTCAGGAGGCCGTTGATGCACTTATAGATAAT
GGTAGGAGAGGAAGGACTGTTGTTGGAGCAAATAATAGAGCTCTAAAGTCCCTAAGTGACATAATTGAAGGAAAACAAGG
AAGATTCAGACAGAATCTTCTTGGAAAACGTGTTGACTATTCAGGGAGATCTGTAATAGTTGTGGGTCCTAAATTAAAAA
TGCATCAGTGTGGACTCCCAAAAGAAATGGCGATAGAGCTCTTTCAACCTTTTGTAATTCATAGATTAATACGACAAAAT
ATTGTGAATAATATTAAAGCTGCAAAAAAATTAATACAAAAAGCCGATGACGAAGTTATGCAGGTCCTTCAGGAAGTTAT
TGAAGGCCATCCAATTCTCTTAAATAGAGCCCCTACTCTGCATCGTTTGGGAATTCAAGCTTTTGAACCGAAATTAGTTG
GAGGTAGAGCAATACAACTTCACCCTTTAGTTTGTCCCGCTTTCAATGCTGACTTTGATGGAGATCAAATGGCAGTTCAT
GTTCCCTTAGCTCTTGAGGCACAAACCGAAGCACGCATGCTTATGCTAGCCAGTAATAATATTCTTTCTCCTGCCACTGG
GGAACCTATTGTGACTCCATCACAAGATATGGTTTTGGGATCTTATTATCTAACAGCTTTGCAACCGAATTATCAAAAAC
CAGAATTCGGAGATAATAAGACTACTTTTGCTTCATTAGAAGATGTTATTTTTGCTTTTGAAGATAAAAGACTCAGCCTT
CATGAATGGATCTGGGTTAGATTTAATGGAGAAGTTGAAGATGAAGACGAAATGCTTAGCCCACAAAAAACTAAAGAGCT
AGAAGATGGCTCAAGATTAGAAATCTGGAATTTAAGAAGGGACAGATTTGGCTCTGATAATAATTTAATAAGTAGATTTG
TACTGACAACTGTTGGGAGAGTAGTTATGAACTATACCATCATCGATTCTGTTTCTAAAACGTAA

Upstream 100 bases:

>100_bases
GAAATACTCCATCAAGGCCTACTTACGAATCACTAGGAACCTCTGAATATGAGGAAGATTAAAAACTTAATTAAAACTCT
TTAATTTAAATTCGCCAAAA

Downstream 100 bases:

>100_bases
TCTTTAAAAACTTTTTTCATTTATTTAAAAATCATGACTTCATCTAAACCTAAAAAAACATCTAGAGTACGTAAAACCAC
TAAAAACTCAAAAAAGAACA

Product: DNA-directed RNA polymerase subunit gamma

Products: NA

Alternate protein names: RNAP subunit gamma; RNA polymerase subunit gamma; Transcriptase subunit gamma [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MTNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYK
RVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWYLKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDPGDHKELK
YKQLLTEDEWLEIEDEIYAEDSTIENEPFVGIGAEALKQLLEDLDLHQIAEELREEITNSKGQKRAKLIKRIRVIDNFIA
TNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDN
GRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQN
IVNNIKAAKKLIQKADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVH
VPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNYQKPEFGDNKTTFASLEDVIFAFEDKRLSL
HEWIWVRFNGEVEDEDEMLSPQKTKELEDGSRLEIWNLRRDRFGSDNNLISRFVLTTVGRVVMNYTIIDSVSKT

Sequences:

>Translated_634_residues
MTNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYK
RVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWYLKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDPGDHKELK
YKQLLTEDEWLEIEDEIYAEDSTIENEPFVGIGAEALKQLLEDLDLHQIAEELREEITNSKGQKRAKLIKRIRVIDNFIA
TNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDN
GRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQN
IVNNIKAAKKLIQKADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVH
VPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNYQKPEFGDNKTTFASLEDVIFAFEDKRLSL
HEWIWVRFNGEVEDEDEMLSPQKTKELEDGSRLEIWNLRRDRFGSDNNLISRFVLTTVGRVVMNYTIIDSVSKT
>Mature_633_residues
TNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYKR
VRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWYLKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDPGDHKELKY
KQLLTEDEWLEIEDEIYAEDSTIENEPFVGIGAEALKQLLEDLDLHQIAEELREEITNSKGQKRAKLIKRIRVIDNFIAT
NAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNG
RRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNI
VNNIKAAKKLIQKADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVHV
PLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNYQKPEFGDNKTTFASLEDVIFAFEDKRLSLH
EWIWVRFNGEVEDEDEMLSPQKTKELEDGSRLEIWNLRRDRFGSDNNLISRFVLTTVGRVVMNYTIIDSVSKT

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=490, Percent_Identity=26.734693877551, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI39725938, Length=321, Percent_Identity=28.9719626168224, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI103471997, Length=224, Percent_Identity=31.6964285714286, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI2367335, Length=524, Percent_Identity=62.2137404580153, Blast_Score=692, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=308, Percent_Identity=32.1428571428571, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71987878, Length=305, Percent_Identity=30.8196721311475, Blast_Score=142, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71998295, Length=347, Percent_Identity=24.4956772334294, Blast_Score=96, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320061, Length=498, Percent_Identity=27.5100401606426, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6324690, Length=235, Percent_Identity=35.3191489361702, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324917, Length=301, Percent_Identity=23.5880398671096, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17530899, Length=488, Percent_Identity=26.0245901639344, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281360912, Length=526, Percent_Identity=26.425855513308, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17647875, Length=337, Percent_Identity=28.1899109792285, Blast_Score=109, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR012755 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 72503; Mature: 72371

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGL
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCH
FCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWY
HHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCEEEEECCHHHHHH
LKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDPGDHKELKYKQLLTEDEWLEIEDEIYAE
HCCHHHHHHHHHHCCHHHHHHEEEEEEEEEECCCCCCHHHHHHHCCCCCCEEECHHHCCC
DSTIENEPFVGIGAEALKQLLEDLDLHQIAEELREEITNSKGQKRAKLIKRIRVIDNFIA
CCCCCCCCCEECCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPE
CCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCH
IIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDY
HEECCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQKADDEVM
CCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVH
HHHHHHHCCCCEEEECCCCHHHHCCHHCCCEEECCEEEEEECEECCCCCCCCCCCCEEEE
VPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNYQKPEFGDNK
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEHHEEEEEECCCCCCCCCCCCC
TTFASLEDVIFAFEDKRLSLHEWIWVRFNGEVEDEDEMLSPQKTKELEDGSRLEIWNLRR
CHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHCCCHHHHHCCCCCEEEEEECHH
DRFGSDNNLISRFVLTTVGRVVMNYTIIDSVSKT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGL
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCH
FCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWY
HHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCEEEEECCHHHHHH
LKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDPGDHKELKYKQLLTEDEWLEIEDEIYAE
HCCHHHHHHHHHHCCHHHHHHEEEEEEEEEECCCCCCHHHHHHHCCCCCCEEECHHHCCC
DSTIENEPFVGIGAEALKQLLEDLDLHQIAEELREEITNSKGQKRAKLIKRIRVIDNFIA
CCCCCCCCCEECCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPE
CCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCH
IIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDY
HEECCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQKADDEVM
CCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVH
HHHHHHHCCCCEEEECCCCHHHHCCHHCCCEEECCEEEEEECEECCCCCCCCCCCCEEEE
VPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNYQKPEFGDNK
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEHHEEEEEECCCCCCCCCCCCC
TTFASLEDVIFAFEDKRLSLHEWIWVRFNGEVEDEDEMLSPQKTKELEDGSRLEIWNLRR
CHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHCCCHHHHHCCCCCEEEEEECHH
DRFGSDNNLISRFVLTTVGRVVMNYTIIDSVSKT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA