Click here to switch to the map view.

The map label for this gene is des [H]

Identifier: 123969119

GI number: 123969119

Start: 1352826

End: 1353932

Strand: Direct

Name: des [H]

Synonym: A9601_15871

Alternate gene names: 123969119

Gene position: 1352826-1353932 (Clockwise)

Preceding gene: 123969118

Following gene: 123969121

Centisome position: 81.01

GC content: 28.91

Gene sequence:

>1107_bases
ATGCCTAAAGTATATAGAGGTGAATTTTTAATAAAGCCATTTCTAAAAAGAAATAATTTTAGAGCTTCTTATCAAATTAT
TTCTACCATCATTCCGATAATCTCAATTTGGTTAATCATCTACCACATCACAAATCAACCTTTTTCATTATTGATTAAAG
GATTTCTATTAATACCTTCGATAGTTCTACTAACTCTATTCTCTTCTCGAACATTCTCATTAATGCATGATTGCGGTCAT
AATTCTCTTTTTACAAAACGGAAATTAAACCGCTTATTTGGATTTTTACTTGGCTTGGTTAATGGTATTCCACAAAAGTC
ATGGTCGATTGATCATGCATTTCATCATAGAAATAATGGAAATTGGGAAATTTATAAAGGGCCCGTAGATGTTTTAAGTC
TTGAAGATTATGCATCCCTTACAAAAAGAGAGCAAATATTTTATAAAGTAAGTCGAAACTGGATTATGCTTTTCCCTGGC
GGTTTTTTTTACTTGGTTTTAAAACCCAGATTAGGACTTATTATTATTATTTTTAATTTAATTAAAGATATATTGAAAGA
GACTTTTATCAAAATCAAAAACAGACAAATTTCTCAACTTCTAGCTATTAATTCAAGAGTCAAACCACCTTTTTCTGATT
ATGGAGATAATTTCGGTGAACTAAGTGAATTAATAATCAATAACATAGTAGTAATAATAGGCTGGATTTTTATGTGCAAA
TGGTTGGGGATAGTTTTTTTCTTATCATTTTATTCCATTGTATTAACATTATCAGCAGCAATTTTAATGTGTGTTTTTTT
CGTACAACATAACTATGAGAATGCGTATGCTAAAAATACAAAAAATTGGGATCTCATCGATGGAGCTATTTTAGGTAGTA
GCAATTTAGATATCCCTAATTGGCTAAATTGGTTTTTAGCAGACATATCCTTCCACAGCATTCATCATCTCTCTGAGAGA
ATACCAAATTACAACTTAAGAGCTTGTCATAAAGCAAACATTCATTTGCTCCAACAATCAAAGTTCTTAAAATTAAGAGA
TTTTTATAACTGCTTCAAATATATTATTTGGGATAATAAAAATGAAAAATTAATTCCTATAAGTTAA

Upstream 100 bases:

>100_bases
TAAAGAATTTATTCTTTAGTATGATTTTTAAAATTTTTTATTGTTTATTAAATAATCAATACTTTTTAAAAATTGTTAGT
ATCAAAAAAAAAAGAGAAAT

Downstream 100 bases:

>100_bases
TACCTAATTCAATCTTCTTCTCAATTTTCTTTTTATGGGAATACTGCTATAAGCATGAGTTCCTATAGATGGAGGCAAGT
CATTTTTTAAAGGATGCATA

Product: Fatty acid desaturase, type 2

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MPKVYRGEFLIKPFLKRNNFRASYQIISTIIPIISIWLIIYHITNQPFSLLIKGFLLIPSIVLLTLFSSRTFSLMHDCGH
NSLFTKRKLNRLFGFLLGLVNGIPQKSWSIDHAFHHRNNGNWEIYKGPVDVLSLEDYASLTKREQIFYKVSRNWIMLFPG
GFFYLVLKPRLGLIIIIFNLIKDILKETFIKIKNRQISQLLAINSRVKPPFSDYGDNFGELSELIINNIVVIIGWIFMCK
WLGIVFFLSFYSIVLTLSAAILMCVFFVQHNYENAYAKNTKNWDLIDGAILGSSNLDIPNWLNWFLADISFHSIHHLSER
IPNYNLRACHKANIHLLQQSKFLKLRDFYNCFKYIIWDNKNEKLIPIS

Sequences:

>Translated_368_residues
MPKVYRGEFLIKPFLKRNNFRASYQIISTIIPIISIWLIIYHITNQPFSLLIKGFLLIPSIVLLTLFSSRTFSLMHDCGH
NSLFTKRKLNRLFGFLLGLVNGIPQKSWSIDHAFHHRNNGNWEIYKGPVDVLSLEDYASLTKREQIFYKVSRNWIMLFPG
GFFYLVLKPRLGLIIIIFNLIKDILKETFIKIKNRQISQLLAINSRVKPPFSDYGDNFGELSELIINNIVVIIGWIFMCK
WLGIVFFLSFYSIVLTLSAAILMCVFFVQHNYENAYAKNTKNWDLIDGAILGSSNLDIPNWLNWFLADISFHSIHHLSER
IPNYNLRACHKANIHLLQQSKFLKLRDFYNCFKYIIWDNKNEKLIPIS
>Mature_367_residues
PKVYRGEFLIKPFLKRNNFRASYQIISTIIPIISIWLIIYHITNQPFSLLIKGFLLIPSIVLLTLFSSRTFSLMHDCGHN
SLFTKRKLNRLFGFLLGLVNGIPQKSWSIDHAFHHRNNGNWEIYKGPVDVLSLEDYASLTKREQIFYKVSRNWIMLFPGG
FFYLVLKPRLGLIIIIFNLIKDILKETFIKIKNRQISQLLAINSRVKPPFSDYGDNFGELSELIINNIVVIIGWIFMCKW
LGIVFFLSFYSIVLTLSAAILMCVFFVQHNYENAYAKNTKNWDLIDGAILGSSNLDIPNWLNWFLADISFHSIHHLSERI
PNYNLRACHKANIHLLQQSKFLKLRDFYNCFKYIIWDNKNEKLIPIS

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 43089; Mature: 42958

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVYRGEFLIKPFLKRNNFRASYQIISTIIPIISIWLIIYHITNQPFSLLIKGFLLIPS
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IVLLTLFSSRTFSLMHDCGHNSLFTKRKLNRLFGFLLGLVNGIPQKSWSIDHAFHHRNNG
HHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCC
NWEIYKGPVDVLSLEDYASLTKREQIFYKVSRNWIMLFPGGFFYLVLKPRLGLIIIIFNL
CEEEEECCCCEEEHHHHHHHHHHHHHHHEECCCEEEEECCCEEEEEECCCCCHHHHHHHH
IKDILKETFIKIKNRQISQLLAINSRVKPPFSDYGDNFGELSELIINNIVVIIGWIFMCK
HHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
WLGIVFFLSFYSIVLTLSAAILMCVFFVQHNYENAYAKNTKNWDLIDGAILGSSNLDIPN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEECCCCCCCHH
WLNWFLADISFHSIHHLSERIPNYNLRACHKANIHLLQQSKFLKLRDFYNCFKYIIWDNK
HHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHEEHHHHHHHHHHHHHHHHHHEECCC
NEKLIPIS
CCEEECCC
>Mature Secondary Structure 
PKVYRGEFLIKPFLKRNNFRASYQIISTIIPIISIWLIIYHITNQPFSLLIKGFLLIPS
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IVLLTLFSSRTFSLMHDCGHNSLFTKRKLNRLFGFLLGLVNGIPQKSWSIDHAFHHRNNG
HHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCC
NWEIYKGPVDVLSLEDYASLTKREQIFYKVSRNWIMLFPGGFFYLVLKPRLGLIIIIFNL
CEEEEECCCCEEEHHHHHHHHHHHHHHHEECCCEEEEECCCEEEEEECCCCCHHHHHHHH
IKDILKETFIKIKNRQISQLLAINSRVKPPFSDYGDNFGELSELIINNIVVIIGWIFMCK
HHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
WLGIVFFLSFYSIVLTLSAAILMCVFFVQHNYENAYAKNTKNWDLIDGAILGSSNLDIPN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEECCCCCCCHH
WLNWFLADISFHSIHHLSERIPNYNLRACHKANIHLLQQSKFLKLRDFYNCFKYIIWDNK
HHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHEEHHHHHHHHHHHHHHHHHHEECCC
NEKLIPIS
CCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]