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The map label for this gene is pyrF [H]

Identifier: 123969060

GI number: 123969060

Start: 1308511

End: 1309239

Strand: Reverse

Name: pyrF [H]

Synonym: A9601_15281

Alternate gene names: 123969060

Gene position: 1309239-1308511 (Counterclockwise)

Preceding gene: 123969061

Following gene: 123969052

Centisome position: 78.4

GC content: 30.04

Gene sequence:

>729_bases
ATGAATAAAAGATTTAATTCAGAAGATAAAATAATATTGGCAATTGATGGATTAGATTTAAGTCAAGCAAAATTACTTCT
GGAAAAATGTCCCCATGTTAAGTGGGTGAAAGTTGGTTTAGAGCTTTTTGTTAGGGAAGGTCCAAGAGTTATTGAAATAT
TAAAAGGTTTAAATAAAAAAATTTTTTTAGACTTAAAATTTCATGATATTCCAAATACCATGAGTGCAGCATGTTTCCAA
GTTTCAAAATTAGGAGTTGATATAATTTCTATTCATGCTTCAGCAGGTCTAAAAGCCCTTAAGGATTCGAAGAAAGCATC
TTTAGAAGGAGCCACATCAGTCAGTGTTAAACCTCCATTTGTTGTAGGAATAACTGTTTTAACAAGCTTTTCTCTTAAAG
ATTTTCAAACTGATCTTGATAGAAATAATTCAATTGAAGAAAATGTATTGAGACTTGCAAAATTGTCTTTTGATGCTGGA
TTAGATGGATGTGTTTGTTCCCCTTGGGAGGTAAAAATGTTGAGATCTAACTATAAGAATAATTTTGAACTTATTACACC
AGGAATCAGATTAAATATTGATAGTAAAGATGATCAAAATAGAATTATGACACCCCATGAAGCTATAGATAATGGCGCTT
CTAAGTTAGTCATTGGTAGATCAATATCAAAAGCTATAGATCCTAATATGGCTCTAATAGAAATATTTAAATCTATTGAT
TCTGATTAA

Upstream 100 bases:

>100_bases
AACAAATCCTGATTTAGTTTTTAATTCAAAAAATGATTTGGAAGGGAAAATTTTGCAAATTGGAAAAAAAATAATTAAGA
GGTTTGAAAACTAAAAATTG

Downstream 100 bases:

>100_bases
TTTTAGATTCTTCTCCCTTAATCAATCTTTTAATGTTTGTTCTATGTTTCCAGATTACTAATAATGCCACAATTAAACTT
ATAAAAAAATATGAGTGAAT

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNKRFNSEDKIILAIDGLDLSQAKLLLEKCPHVKWVKVGLELFVREGPRVIEILKGLNKKIFLDLKFHDIPNTMSAACFQ
VSKLGVDIISIHASAGLKALKDSKKASLEGATSVSVKPPFVVGITVLTSFSLKDFQTDLDRNNSIEENVLRLAKLSFDAG
LDGCVCSPWEVKMLRSNYKNNFELITPGIRLNIDSKDDQNRIMTPHEAIDNGASKLVIGRSISKAIDPNMALIEIFKSID
SD

Sequences:

>Translated_242_residues
MNKRFNSEDKIILAIDGLDLSQAKLLLEKCPHVKWVKVGLELFVREGPRVIEILKGLNKKIFLDLKFHDIPNTMSAACFQ
VSKLGVDIISIHASAGLKALKDSKKASLEGATSVSVKPPFVVGITVLTSFSLKDFQTDLDRNNSIEENVLRLAKLSFDAG
LDGCVCSPWEVKMLRSNYKNNFELITPGIRLNIDSKDDQNRIMTPHEAIDNGASKLVIGRSISKAIDPNMALIEIFKSID
SD
>Mature_242_residues
MNKRFNSEDKIILAIDGLDLSQAKLLLEKCPHVKWVKVGLELFVREGPRVIEILKGLNKKIFLDLKFHDIPNTMSAACFQ
VSKLGVDIISIHASAGLKALKDSKKASLEGATSVSVKPPFVVGITVLTSFSLKDFQTDLDRNNSIEENVLRLAKLSFDAG
LDGCVCSPWEVKMLRSNYKNNFELITPGIRLNIDSKDDQNRIMTPHEAIDNGASKLVIGRSISKAIDPNMALIEIFKSID
SD

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=239, Percent_Identity=35.1464435146443, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 26780; Mature: 26780

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRFNSEDKIILAIDGLDLSQAKLLLEKCPHVKWVKVGLELFVREGPRVIEILKGLNKK
CCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEHHHHHHHHCCCCHHHHHHHCCCCE
IFLDLKFHDIPNTMSAACFQVSKLGVDIISIHASAGLKALKDSKKASLEGATSVSVKPPF
EEEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHCCHHHCCCCCCEEECCCCE
VVGITVLTSFSLKDFQTDLDRNNSIEENVLRLAKLSFDAGLDGCVCSPWEVKMLRSNYKN
EEEEHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCC
NFELITPGIRLNIDSKDDQNRIMTPHEAIDNGASKLVIGRSISKAIDPNMALIEIFKSID
CCEEECCCEEEEECCCCCCCCCCCCHHHHCCCCCEEEECCCHHHHCCCCHHHHHHHHHHC
SD
CC
>Mature Secondary Structure
MNKRFNSEDKIILAIDGLDLSQAKLLLEKCPHVKWVKVGLELFVREGPRVIEILKGLNKK
CCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEHHHHHHHHCCCCHHHHHHHCCCCE
IFLDLKFHDIPNTMSAACFQVSKLGVDIISIHASAGLKALKDSKKASLEGATSVSVKPPF
EEEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHCCHHHCCCCCCEEECCCCE
VVGITVLTSFSLKDFQTDLDRNNSIEENVLRLAKLSFDAGLDGCVCSPWEVKMLRSNYKN
EEEEHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCC
NFELITPGIRLNIDSKDDQNRIMTPHEAIDNGASKLVIGRSISKAIDPNMALIEIFKSID
CCEEECCCEEEEECCCCCCCCCCCCHHHHCCCCCEEEECCCHHHHCCCCHHHHHHHHHHC
SD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA