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The map label for this gene is rfbF [H]

Identifier: 123968940

GI number: 123968940

Start: 1177969

End: 1178742

Strand: Reverse

Name: rfbF [H]

Synonym: A9601_14071

Alternate gene names: 123968940

Gene position: 1178742-1177969 (Counterclockwise)

Preceding gene: 123968941

Following gene: 123968939

Centisome position: 70.59

GC content: 33.72

Gene sequence:

>774_bases
TTGACTAAAGCAGTAATTTTAGCTGGCGGACTAGGGACACGTTTGAGCGAAGAGACATCCTTAAAGCCTAAACCAATGAT
TGAGATTGGGGGGAAACCAATTCTTTGGCACATCTTAAAAATATTTAGTCATTACGAGATTAATGATTTTATTATATGCT
GCGGTTACAAGGGATATTTGATAAAAGAATATTTTGCGAATTATTTTTTACATACAAGTGATATAACTTTTCATATGGAT
AATGATAACTATATGGAAGTACATCAAAGAAAAAGCGAACCCTGGAAAGTAACCTTAGTTGATACTGGAGACCTGACTCA
AACTGGAGGCAGACTTAAGAGAGTTTTTAAATATTTAGATTCTGAGACTTTTTGTTTTACATATGGTGATGGGGTCTCTG
ATGTTAATATTAAAGATCTTCTTGAAAAACATAAAGAGTCAGAAAAACTTGCTACTGTGACTACCGTTAAGCCTCCAGGA
AGATTTGGAGCTTTAAGATTAGATAATGATTTAGTATCAAATTTCCAGGAAAAACCAGATGGCGATAACTCTTGGATAAA
TGGTGGTTTTTTCGTCTTAGAACCTGAAGTAGTAGAACTTATTGAAAATGATCAAGTTATATGGGAAGAAGATATATTAC
CTAAATTGGTCTTGAAAAATCAGTTAGGAGCATATAAACATAGGGGTTTTTGGCACCCAATGGATACTTTGCGCGATAGA
AATTCTCTAGATTTACTATGCAAAAAAGGAAATGCACCATGGATAAAATGGTAA

Upstream 100 bases:

>100_bases
TTAAATTAAAAAATTTAACGAATTAACATATGTTAAACTTTCTAAAATCTTAAATTAAAATTTATTGGATTTTATTTAAG
ACCACACTTTTAAAATTGAT

Downstream 100 bases:

>100_bases
AATTTGAAAATCAATTTGTTTGATTTTGATTTTATGACCTAAGGTTATAAAATCTAAGAAGTTTAAATGCTTTAAATGAT
AATATTAATCTGCAATTCAA

Product: glucose-1-phosphate cytidylyltransferase

Products: NA

Alternate protein names: CDP-glucose pyrophosphorylase [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTKAVILAGGLGTRLSEETSLKPKPMIEIGGKPILWHILKIFSHYEINDFIICCGYKGYLIKEYFANYFLHTSDITFHMD
NDNYMEVHQRKSEPWKVTLVDTGDLTQTGGRLKRVFKYLDSETFCFTYGDGVSDVNIKDLLEKHKESEKLATVTTVKPPG
RFGALRLDNDLVSNFQEKPDGDNSWINGGFFVLEPEVVELIENDQVIWEEDILPKLVLKNQLGAYKHRGFWHPMDTLRDR
NSLDLLCKKGNAPWIKW

Sequences:

>Translated_257_residues
MTKAVILAGGLGTRLSEETSLKPKPMIEIGGKPILWHILKIFSHYEINDFIICCGYKGYLIKEYFANYFLHTSDITFHMD
NDNYMEVHQRKSEPWKVTLVDTGDLTQTGGRLKRVFKYLDSETFCFTYGDGVSDVNIKDLLEKHKESEKLATVTTVKPPG
RFGALRLDNDLVSNFQEKPDGDNSWINGGFFVLEPEVVELIENDQVIWEEDILPKLVLKNQLGAYKHRGFWHPMDTLRDR
NSLDLLCKKGNAPWIKW
>Mature_256_residues
TKAVILAGGLGTRLSEETSLKPKPMIEIGGKPILWHILKIFSHYEINDFIICCGYKGYLIKEYFANYFLHTSDITFHMDN
DNYMEVHQRKSEPWKVTLVDTGDLTQTGGRLKRVFKYLDSETFCFTYGDGVSDVNIKDLLEKHKESEKLATVTTVKPPGR
FGALRLDNDLVSNFQEKPDGDNSWINGGFFVLEPEVVELIENDQVIWEEDILPKLVLKNQLGAYKHRGFWHPMDTLRDRN
SLDLLCKKGNAPWIKW

Specific function: Involved in the biosynthesis of the tyvelose, a 3,6- dideoxyhexose found in the O-antigen of the surface lipopolysaccharides. It catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate. This enzyme can utilize either CTP or UTP as the nucle

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate cytidylyltransferase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI133931050, Length=246, Percent_Identity=26.0162601626016, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320148, Length=244, Percent_Identity=28.2786885245902, Blast_Score=90, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21355443, Length=250, Percent_Identity=27.6, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644084, Length=250, Percent_Identity=27.6, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013446
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.33 [H]

Molecular weight: Translated: 29618; Mature: 29487

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKAVILAGGLGTRLSEETSLKPKPMIEIGGKPILWHILKIFSHYEINDFIICCGYKGYL
CCCEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCHH
IKEYFANYFLHTSDITFHMDNDNYMEVHQRKSEPWKVTLVDTGDLTQTGGRLKRVFKYLD
HHHHHHHHEEEECCEEEEECCCCEEHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHC
SETFCFTYGDGVSDVNIKDLLEKHKESEKLATVTTVKPPGRFGALRLDNDLVSNFQEKPD
CCEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECHHHHHHHHHCCC
GDNSWINGGFFVLEPEVVELIENDQVIWEEDILPKLVLKNQLGAYKHRGFWHPMDTLRDR
CCCCEECCCEEEECHHHHHHHCCCCEEEHHHHHHHHHHHHHHCHHHHCCCCCCHHHHCCC
NSLDLLCKKGNAPWIKW
CCEEEEEECCCCCCCCC
>Mature Secondary Structure 
TKAVILAGGLGTRLSEETSLKPKPMIEIGGKPILWHILKIFSHYEINDFIICCGYKGYL
CCEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCHH
IKEYFANYFLHTSDITFHMDNDNYMEVHQRKSEPWKVTLVDTGDLTQTGGRLKRVFKYLD
HHHHHHHHEEEECCEEEEECCCCEEHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHC
SETFCFTYGDGVSDVNIKDLLEKHKESEKLATVTTVKPPGRFGALRLDNDLVSNFQEKPD
CCEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECHHHHHHHHHCCC
GDNSWINGGFFVLEPEVVELIENDQVIWEEDILPKLVLKNQLGAYKHRGFWHPMDTLRDR
CCCCEECCCEEEECHHHHHHHCCCCEEEHHHHHHHHHHHHHHCHHHHCCCCCCHHHHCCC
NSLDLLCKKGNAPWIKW
CCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]