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The map label for this gene is trxB [H]

Identifier: 123968858

GI number: 123968858

Start: 1102542

End: 1103918

Strand: Direct

Name: trxB [H]

Synonym: A9601_13251

Alternate gene names: 123968858

Gene position: 1102542-1103918 (Clockwise)

Preceding gene: 123968857

Following gene: 123968863

Centisome position: 66.02

GC content: 35.73

Gene sequence:

>1377_bases
ATGGAGAATAAAGAGAACAATTCAAACGTAGAAAATGTTGTAATCATAGGCTCAGGACCTGCGGGTTATACCGCTGCAAT
ATATGCCGCAAGAGCAAATCTTCAACCATTACTCGTAACAGGATTTAATTCAGGTGGAATTCCTGGTGGCCAATTAATGA
CTACAACATTTGTTGAAAATTATCCAGGGTTCCCAGATGGAGTACTAGGTCCTGAATTAATGGATCTTATGAAGGCTCAA
GCAGAAAGATGGGGTACTAATTTATACGAAAGTGATGTTGTCTCAATAAATACTGATTCACATCCCTTTGAATTAAAAAC
TTTAGAAGGGACTATAAAAACTAACTCAATTATTATTGCAACTGGAGCAAGTGCAAATAGATTAGGAGTGATAAATGAAG
ATAAATTCTGGAGTAAAGGAATAAGTGCTTGTGCAATCTGTGATGGAGCAACTCCACAATTCAGAGATGAAGAATTAGCT
GTTATAGGAGGAGGAGACTCTGCATGTGAAGAAGCAGCATACCTCACAAAGTATGGCAGCAAGGTTCATTTAATTGTCAG
ATCAGAAAAATTAAGGGCTAGCGCAGCAATGGTTGATAGAGTAAAAGCTAATCCAAAGATAGAAATCCATTGGAACACAA
AAGTTAATAAAGCTGATGGTTTTGAATGGCTTGAGAAAATAGAAACTATTCACTCTCAGGAAGGTAAAGGAGAAATCAAT
ATAAAAGGTCTTTTTTATGCGATAGGACACACACCAAATACGAAGTTCTTAGACAACAAAATTGATTTAGATAATAAAGG
TTATATTGCTTGCAAATCAGGAAGACCAGAAACATCTATTGAAGGCATTTTTGCAGCAGGTGATGTTGTTGATTCTGAGT
GGAGACAAGGAGTTACAGCTGCAGGAACTGGATGCATGGCAGCATTAGCTACCGAAAGGTGGCTAGCAGAGAAAAACTTA
GCAAAAACCATAGTCAGAGAAACACCCGAACCAGAAAAAAAACTTAATTCATCAGACTTTAATGAAGAAGAAGTTAATGA
AGATACTTTCGATTCAAATTCTGAATGGCAAAAAGGCAGTTATGCATTAAGGAAACTTTATCACGAGAGTAAAAAACCTA
TCTTGGTAATTTTTAGTTCCCCAAGTTGTGGCCCATGCCATGTATTAAAACCTCAATTAAAAAGGGTAATCAAAGAACTT
GATGGTGCAGTGCTTGGGGTTGAAATAGATATTGATAAAGATCAAAATATTGCAAAACAAGCTGGTATTAACGGCACACC
AACAGTTCAACTTTTTAAAGAAAAATTATTAAAAAAGCAATGGCAAGGTGTTAAACAAAGAAGTGAGTTTAAAGAAGCAA
TAAAAAATATTATCTAA

Upstream 100 bases:

>100_bases
GACCAAAAAGTCAACGATTAAATAACAAGTCGATCGAGTGAAACCCGCCCTACATAATTTGGGTTTGTTTATTATTATAA
GTAGTGAATTTAGCAAATAA

Downstream 100 bases:

>100_bases
AATAACTGGTTACTTATTATTCCTCTTGGGGTTATTTTTATTAGTTGTGGGTTTAGAACCCCCTGCATTTCTTTCTCTAT
AAGTTATCCTTCCTCTAGAA

Product: putative thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MENKENNSNVENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVENYPGFPDGVLGPELMDLMKAQ
AERWGTNLYESDVVSINTDSHPFELKTLEGTIKTNSIIIATGASANRLGVINEDKFWSKGISACAICDGATPQFRDEELA
VIGGGDSACEEAAYLTKYGSKVHLIVRSEKLRASAAMVDRVKANPKIEIHWNTKVNKADGFEWLEKIETIHSQEGKGEIN
IKGLFYAIGHTPNTKFLDNKIDLDNKGYIACKSGRPETSIEGIFAAGDVVDSEWRQGVTAAGTGCMAALATERWLAEKNL
AKTIVRETPEPEKKLNSSDFNEEEVNEDTFDSNSEWQKGSYALRKLYHESKKPILVIFSSPSCGPCHVLKPQLKRVIKEL
DGAVLGVEIDIDKDQNIAKQAGINGTPTVQLFKEKLLKKQWQGVKQRSEFKEAIKNII

Sequences:

>Translated_458_residues
MENKENNSNVENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVENYPGFPDGVLGPELMDLMKAQ
AERWGTNLYESDVVSINTDSHPFELKTLEGTIKTNSIIIATGASANRLGVINEDKFWSKGISACAICDGATPQFRDEELA
VIGGGDSACEEAAYLTKYGSKVHLIVRSEKLRASAAMVDRVKANPKIEIHWNTKVNKADGFEWLEKIETIHSQEGKGEIN
IKGLFYAIGHTPNTKFLDNKIDLDNKGYIACKSGRPETSIEGIFAAGDVVDSEWRQGVTAAGTGCMAALATERWLAEKNL
AKTIVRETPEPEKKLNSSDFNEEEVNEDTFDSNSEWQKGSYALRKLYHESKKPILVIFSSPSCGPCHVLKPQLKRVIKEL
DGAVLGVEIDIDKDQNIAKQAGINGTPTVQLFKEKLLKKQWQGVKQRSEFKEAIKNII
>Mature_458_residues
MENKENNSNVENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVENYPGFPDGVLGPELMDLMKAQ
AERWGTNLYESDVVSINTDSHPFELKTLEGTIKTNSIIIATGASANRLGVINEDKFWSKGISACAICDGATPQFRDEELA
VIGGGDSACEEAAYLTKYGSKVHLIVRSEKLRASAAMVDRVKANPKIEIHWNTKVNKADGFEWLEKIETIHSQEGKGEIN
IKGLFYAIGHTPNTKFLDNKIDLDNKGYIACKSGRPETSIEGIFAAGDVVDSEWRQGVTAAGTGCMAALATERWLAEKNL
AKTIVRETPEPEKKLNSSDFNEEEVNEDTFDSNSEWQKGSYALRKLYHESKKPILVIFSSPSCGPCHVLKPQLKRVIKEL
DGAVLGVEIDIDKDQNIAKQAGINGTPTVQLFKEKLLKKQWQGVKQRSEFKEAIKNII

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=43.7699680511182, Blast_Score=254, Evalue=9e-69,
Organism=Escherichia coli, GI87081763, Length=323, Percent_Identity=30.030959752322, Blast_Score=124, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6320560, Length=310, Percent_Identity=51.9354838709677, Blast_Score=311, Evalue=1e-85,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=48.5623003194888, Blast_Score=297, Evalue=2e-81,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 50169; Mature: 50169

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKENNSNVENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVEN
CCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEHHHC
YPGFPDGVLGPELMDLMKAQAERWGTNLYESDVVSINTDSHPFELKTLEGTIKTNSIIIA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEECEEEECEEEEE
TGASANRLGVINEDKFWSKGISACAICDGATPQFRDEELAVIGGGDSACEEAAYLTKYGS
ECCCCCEEEECCCCHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC
KVHLIVRSEKLRASAAMVDRVKANPKIEIHWNTKVNKADGFEWLEKIETIHSQEGKGEIN
EEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEE
IKGLFYAIGHTPNTKFLDNKIDLDNKGYIACKSGRPETSIEGIFAAGDVVDSEWRQGVTA
EEEEEEEECCCCCCCCCCCEECCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHCCCCC
AGTGCMAALATERWLAEKNLAKTIVRETPEPEKKLNSSDFNEEEVNEDTFDSNSEWQKGS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHCCCCCCCCCCCCCHHH
YALRKLYHESKKPILVIFSSPSCGPCHVLKPQLKRVIKELDGAVLGVEIDIDKDQNIAKQ
HHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEECCCCCCHHHH
AGINGTPTVQLFKEKLLKKQWQGVKQRSEFKEAIKNII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENKENNSNVENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVEN
CCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEHHHC
YPGFPDGVLGPELMDLMKAQAERWGTNLYESDVVSINTDSHPFELKTLEGTIKTNSIIIA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEECEEEECEEEEE
TGASANRLGVINEDKFWSKGISACAICDGATPQFRDEELAVIGGGDSACEEAAYLTKYGS
ECCCCCEEEECCCCHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC
KVHLIVRSEKLRASAAMVDRVKANPKIEIHWNTKVNKADGFEWLEKIETIHSQEGKGEIN
EEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEE
IKGLFYAIGHTPNTKFLDNKIDLDNKGYIACKSGRPETSIEGIFAAGDVVDSEWRQGVTA
EEEEEEEECCCCCCCCCCCEECCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHCCCCC
AGTGCMAALATERWLAEKNLAKTIVRETPEPEKKLNSSDFNEEEVNEDTFDSNSEWQKGS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHCCCCCCCCCCCCCHHH
YALRKLYHESKKPILVIFSSPSCGPCHVLKPQLKRVIKELDGAVLGVEIDIDKDQNIAKQ
HHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEECCCCCCHHHH
AGINGTPTVQLFKEKLLKKQWQGVKQRSEFKEAIKNII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]