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The map label for this gene is fur [H]

Identifier: 123968665

GI number: 123968665

Start: 952726

End: 953160

Strand: Direct

Name: fur [H]

Synonym: A9601_11321

Alternate gene names: 123968665

Gene position: 952726-953160 (Clockwise)

Preceding gene: 123968663

Following gene: 123968667

Centisome position: 57.05

GC content: 37.47

Gene sequence:

>435_bases
ATGATCAAAAATACGGGGAAAAAAAAGATTTCGGAAACAATGGTAACTAAGCCTGACATTACCAAAAGACAAGAACAACT
TCTTGAAGAACTTAATAAATGTGAAGATGAACTGAGCGGTCAAGAGTTGCATAGACAATTGATTGAAAGCGGAAAAGCTA
TGGGACTGACAACTGTATACAGGAATCTTCAAGTTCTTATAAAGCATGGTTTAATACGTTCTAGACATCTCCCAACAGGA
GAGGTTCTTTACACTCCCGTAGATAGAGACATTCATCATTTGACATGTGTTCAATGTGGTGAGACTTCAAAAATGGAAGG
GTGCCCTGTAAAAGATATTCATACACCCAAAACAAATCCAAAGAAATTCCAATTGTTGTTCCATACCCTGGAGTATTTCG
GACTTTGCCAGAACTGCTATCAAGCACAAAGTTAA

Upstream 100 bases:

>100_bases
GTTCCCATAGCTGGACATAGAATTCCTGAAAAAATAGTTATTATTAAGGGAACAAGCCACCAACTGCTATTAATAAAAGA
CATTAATCTATTGATTCGGT

Downstream 100 bases:

>100_bases
AACTAAATATTTTTTTAATCACAACAATTATTATCCTCAATAGAGCTGATATTTATATCCTCTAATTTATCTTTTATGGA
ATCAGGGCTTCCACAGGCCA

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MIKNTGKKKISETMVTKPDITKRQEQLLEELNKCEDELSGQELHRQLIESGKAMGLTTVYRNLQVLIKHGLIRSRHLPTG
EVLYTPVDRDIHHLTCVQCGETSKMEGCPVKDIHTPKTNPKKFQLLFHTLEYFGLCQNCYQAQS

Sequences:

>Translated_144_residues
MIKNTGKKKISETMVTKPDITKRQEQLLEELNKCEDELSGQELHRQLIESGKAMGLTTVYRNLQVLIKHGLIRSRHLPTG
EVLYTPVDRDIHHLTCVQCGETSKMEGCPVKDIHTPKTNPKKFQLLFHTLEYFGLCQNCYQAQS
>Mature_144_residues
MIKNTGKKKISETMVTKPDITKRQEQLLEELNKCEDELSGQELHRQLIESGKAMGLTTVYRNLQVLIKHGLIRSRHLPTG
EVLYTPVDRDIHHLTCVQCGETSKMEGCPVKDIHTPKTNPKKFQLLFHTLEYFGLCQNCYQAQS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of the fbp protein [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16522; Mature: 16522

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNTGKKKISETMVTKPDITKRQEQLLEELNKCEDELSGQELHRQLIESGKAMGLTTVY
CCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHH
RNLQVLIKHGLIRSRHLPTGEVLYTPVDRDIHHLTCVQCGETSKMEGCPVKDIHTPKTNP
HHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
KKFQLLFHTLEYFGLCQNCYQAQS
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKNTGKKKISETMVTKPDITKRQEQLLEELNKCEDELSGQELHRQLIESGKAMGLTTVY
CCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHH
RNLQVLIKHGLIRSRHLPTGEVLYTPVDRDIHHLTCVQCGETSKMEGCPVKDIHTPKTNP
HHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
KKFQLLFHTLEYFGLCQNCYQAQS
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8406856 [H]