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The map label for this gene is cumB [H]

Identifier: 123968475

GI number: 123968475

Start: 811253

End: 811690

Strand: Reverse

Name: cumB [H]

Synonym: A9601_09421

Alternate gene names: 123968475

Gene position: 811690-811253 (Counterclockwise)

Preceding gene: 123968478

Following gene: 123968473

Centisome position: 48.61

GC content: 35.16

Gene sequence:

>438_bases
ATGAATTCGATATTAAGAAGATCCAAAGAAATTGGAAAAGTTGAACTACCAATATGTTCAATAATTTTAGATGAGAGAGG
AAGATGTATCGGGAGAGGTGTTAACAGTAGGAATATAAATAAAGACCCATTGGGTCATGCTGAGATAATGGCACTTAGGC
AAGCATCTCTAATAAAAAATGATTGGAGATTTAATGAATGTACTATTATCACAAATTTAGAACCTTGTACTATGTGTTCC
TCTGCTCTTATACAAGCGCGGATGGGTAAAGTTATTTTCGGGGCTTACGATAAGAAAAGAGGGGGATTGGGCGGCTCAAT
TGACCTATCAAAACATGAAAGTGCTCATCACAAAATGGAAATAATTGGAGGTATCCTAGAAGATGAATGTAGTCAAATTT
TACAGATTTGGTTCAAAAAGTTGAGGACTCAAAAATAG

Upstream 100 bases:

>100_bases
ATTGTATTCTCAATATTGGTAAATGAGATATATTTTTGAAAATGGAAATAGTAATGAAGATCAACAAAGAAAAACAAATA
ATTCAAAATACACTTTGTGG

Downstream 100 bases:

>100_bases
AAAATTTCTTTAGCTCAGTATCAAATAAGTTTAATAATCTGTCGACATTCTCATCACTTGAGTTAAAGCCCATTAAACCT
ATCCGCCATACCTTACCAGA

Product: putative cytidine/deoxycytidylate deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MNSILRRSKEIGKVELPICSIILDERGRCIGRGVNSRNINKDPLGHAEIMALRQASLIKNDWRFNECTIITNLEPCTMCS
SALIQARMGKVIFGAYDKKRGGLGGSIDLSKHESAHHKMEIIGGILEDECSQILQIWFKKLRTQK

Sequences:

>Translated_145_residues
MNSILRRSKEIGKVELPICSIILDERGRCIGRGVNSRNINKDPLGHAEIMALRQASLIKNDWRFNECTIITNLEPCTMCS
SALIQARMGKVIFGAYDKKRGGLGGSIDLSKHESAHHKMEIIGGILEDECSQILQIWFKKLRTQK
>Mature_145_residues
MNSILRRSKEIGKVELPICSIILDERGRCIGRGVNSRNINKDPLGHAEIMALRQASLIKNDWRFNECTIITNLEPCTMCS
SALIQARMGKVIFGAYDKKRGGLGGSIDLSKHESAHHKMEIIGGILEDECSQILQIWFKKLRTQK

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=130, Percent_Identity=40.7692307692308, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16307; Mature: 16307

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSILRRSKEIGKVELPICSIILDERGRCIGRGVNSRNINKDPLGHAEIMALRQASLIKN
CCHHHHHHHHCCEEECHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHC
DWRFNECTIITNLEPCTMCSSALIQARMGKVIFGAYDKKRGGLGGSIDLSKHESAHHKME
CCCCCCEEEEECCCHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
IIGGILEDECSQILQIWFKKLRTQK
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSILRRSKEIGKVELPICSIILDERGRCIGRGVNSRNINKDPLGHAEIMALRQASLIKN
CCHHHHHHHHCCEEECHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHC
DWRFNECTIITNLEPCTMCSSALIQARMGKVIFGAYDKKRGGLGGSIDLSKHESAHHKME
CCCCCCEEEEECCCHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
IIGGILEDECSQILQIWFKKLRTQK
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]