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The map label for this gene is umuC [H]

Identifier: 123968456

GI number: 123968456

Start: 794799

End: 796085

Strand: Reverse

Name: umuC [H]

Synonym: A9601_09231

Alternate gene names: 123968456

Gene position: 796085-794799 (Counterclockwise)

Preceding gene: 123968457

Following gene: 123968455

Centisome position: 47.67

GC content: 30.77

Gene sequence:

>1287_bases
ATGAGAATTTCAAATATTGATGCAATAGCTCTTATAGATGCCAATAATTTTTACGCGTCATGTGAACAAAATATTAATCC
TCATTTGAGAAATAAACCAGTAGTAATTTTATCTAATAATGACGGATGTATCATTGCAAGAAGCCCTGAAGCGCGAGCTT
TAAAAATTAAAATGGGAACTCCGTATTTTAAGGTCAAAGAAAGACTAAATAAATTAGATGTAGCAGTCTTAAGCTCAAAC
TACTCGCTTTATGGGGATATGAGCAGAAGACTAATGAATTTACTGAAAAATTACTGTGAACAGATAGAAATTTATTCTAT
TGACGAAGCATTCGTCTCGATTTCTAGACCTAATGATGAAAATCTATATCCTTGGGCAAGAAGCATAAGATCATTAATAT
ATCAGAATCTAGGGATTACCATAACAGTAGGAATAGGAGAAAATAAAGTAAGAGCAAAAATTGCTAATAAACTAGCTAAA
AATATTGATTATTCAGCTGGAATATTTGATTTAGCTAGAACCGAAAATGAGAATAATTATTTGAAAAGAATTAGTATAGA
TAAGATATGGGGAGTCGGGAAACAAACCTCTAATTGGTTGCAAAGTAAAGGTATTAAAAATGCGAGAGAACTAAGAGATA
TGGAAGAAAATGAAATCATTAAGAAATTAGGCATCGTAGGGAAAAGACTGCAATTAGAACTGAAAGGCCATAGATGCCTG
CCCATAGAAAAAAACAAGAAATCAAAAAAAGAAATTCAGGTGAGCAGGAGTTTCGGCACGCCTATCACAAAATTAGAAGA
CTTAACTCAAGCACTAGCAACTCACGCAATAAAAGCCTCTGAAAAAATGAGAAGTCAGAATTTGCAATCATCTGATATTA
GAGTATTTGCCAGAACCAGTAAATATTCAAGTCAAAATTATCAAAGAAGTGCTCATAGAAAACTTACAAATGCAACAGAT
GACACAAATAAAATTTTAAAAATAGTAGTTGAATTATCTGAAGAAATTTATAATCCCGAATATAAATTCTCAAAAGCTGG
TGTTTTAATGCAGGATTTAACTAATAGCGAATATTTACAGCAATCAGTTATCAATTACAAATCTCAGAAAGACTTAAAAA
AATCAGCAAATCTTATGAAAACGATTGATTTATTAAATAAAAGATTTAATAACAATGCAATTACATGGGCTATTACAAAA
AATCCACAAAGTTGGAAGATGAATAATAATTTCTTAAGTCGCTCATCTACAACTGATATAGAACAAATCCCAACTATAGT
GAAGTAA

Upstream 100 bases:

>100_bases
ATTTAAAAGCAGAAAATCATAATTATCCTGATTTTAGATTTAAAAACCATATTGATGTACAGATATGGGGAGTTGTTATT
TATTCAATACATAGCTATTT

Downstream 100 bases:

>100_bases
ACAAAATAGAATGGAATTTATATTATTTTTGAGCAAATTAGATAAAGAGATTCTTAACTTATTAATTAAAGCAAACTACA
TAGTTGAAGAAAATAAAATT

Product: putative UmuC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MRISNIDAIALIDANNFYASCEQNINPHLRNKPVVILSNNDGCIIARSPEARALKIKMGTPYFKVKERLNKLDVAVLSSN
YSLYGDMSRRLMNLLKNYCEQIEIYSIDEAFVSISRPNDENLYPWARSIRSLIYQNLGITITVGIGENKVRAKIANKLAK
NIDYSAGIFDLARTENENNYLKRISIDKIWGVGKQTSNWLQSKGIKNARELRDMEENEIIKKLGIVGKRLQLELKGHRCL
PIEKNKKSKKEIQVSRSFGTPITKLEDLTQALATHAIKASEKMRSQNLQSSDIRVFARTSKYSSQNYQRSAHRKLTNATD
DTNKILKIVVELSEEIYNPEYKFSKAGVLMQDLTNSEYLQQSVINYKSQKDLKKSANLMKTIDLLNKRFNNNAITWAITK
NPQSWKMNNNFLSRSSTTDIEQIPTIVK

Sequences:

>Translated_428_residues
MRISNIDAIALIDANNFYASCEQNINPHLRNKPVVILSNNDGCIIARSPEARALKIKMGTPYFKVKERLNKLDVAVLSSN
YSLYGDMSRRLMNLLKNYCEQIEIYSIDEAFVSISRPNDENLYPWARSIRSLIYQNLGITITVGIGENKVRAKIANKLAK
NIDYSAGIFDLARTENENNYLKRISIDKIWGVGKQTSNWLQSKGIKNARELRDMEENEIIKKLGIVGKRLQLELKGHRCL
PIEKNKKSKKEIQVSRSFGTPITKLEDLTQALATHAIKASEKMRSQNLQSSDIRVFARTSKYSSQNYQRSAHRKLTNATD
DTNKILKIVVELSEEIYNPEYKFSKAGVLMQDLTNSEYLQQSVINYKSQKDLKKSANLMKTIDLLNKRFNNNAITWAITK
NPQSWKMNNNFLSRSSTTDIEQIPTIVK
>Mature_428_residues
MRISNIDAIALIDANNFYASCEQNINPHLRNKPVVILSNNDGCIIARSPEARALKIKMGTPYFKVKERLNKLDVAVLSSN
YSLYGDMSRRLMNLLKNYCEQIEIYSIDEAFVSISRPNDENLYPWARSIRSLIYQNLGITITVGIGENKVRAKIANKLAK
NIDYSAGIFDLARTENENNYLKRISIDKIWGVGKQTSNWLQSKGIKNARELRDMEENEIIKKLGIVGKRLQLELKGHRCL
PIEKNKKSKKEIQVSRSFGTPITKLEDLTQALATHAIKASEKMRSQNLQSSDIRVFARTSKYSSQNYQRSAHRKLTNATD
DTNKILKIVVELSEEIYNPEYKFSKAGVLMQDLTNSEYLQQSVINYKSQKDLKKSANLMKTIDLLNKRFNNNAITWAITK
NPQSWKMNNNFLSRSSTTDIEQIPTIVK

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=414, Percent_Identity=36.7149758454106, Blast_Score=274, Evalue=1e-74,
Organism=Escherichia coli, GI1786425, Length=225, Percent_Identity=25.3333333333333, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19923006, Length=304, Percent_Identity=23.3552631578947, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 48981; Mature: 48981

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRISNIDAIALIDANNFYASCEQNINPHLRNKPVVILSNNDGCIIARSPEARALKIKMGT
CCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCEEEEECCCCEEEEECCCCEEEEEEECC
PYFKVKERLNKLDVAVLSSNYSLYGDMSRRLMNLLKNYCEQIEIYSIDEAFVSISRPNDE
CHHHHHHHHHHHEEEEEECCCCEEHHHHHHHHHHHHHHHHHEEEEEECHHHEEECCCCCC
NLYPWARSIRSLIYQNLGITITVGIGENKVRAKIANKLAKNIDYSAGIFDLARTENENNY
CCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCC
LKRISIDKIWGVGKQTSNWLQSKGIKNARELRDMEENEIIKKLGIVGKRLQLELKGHRCL
EEEEEHHHHHCCCCHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCEEC
PIEKNKKSKKEIQVSRSFGTPITKLEDLTQALATHAIKASEKMRSQNLQSSDIRVFARTS
CCCCCCCCHHHEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
KYSSQNYQRSAHRKLTNATDDTNKILKIVVELSEEIYNPEYKFSKAGVLMQDLTNSEYLQ
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHCCCHHHHH
QSVINYKSQKDLKKSANLMKTIDLLNKRFNNNAITWAITKNPQSWKMNNNFLSRSSTTDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEECCCCCCCH
EQIPTIVK
HHCCCCCC
>Mature Secondary Structure
MRISNIDAIALIDANNFYASCEQNINPHLRNKPVVILSNNDGCIIARSPEARALKIKMGT
CCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCEEEEECCCCEEEEECCCCEEEEEEECC
PYFKVKERLNKLDVAVLSSNYSLYGDMSRRLMNLLKNYCEQIEIYSIDEAFVSISRPNDE
CHHHHHHHHHHHEEEEEECCCCEEHHHHHHHHHHHHHHHHHEEEEEECHHHEEECCCCCC
NLYPWARSIRSLIYQNLGITITVGIGENKVRAKIANKLAKNIDYSAGIFDLARTENENNY
CCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCC
LKRISIDKIWGVGKQTSNWLQSKGIKNARELRDMEENEIIKKLGIVGKRLQLELKGHRCL
EEEEEHHHHHCCCCHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCEEC
PIEKNKKSKKEIQVSRSFGTPITKLEDLTQALATHAIKASEKMRSQNLQSSDIRVFARTS
CCCCCCCCHHHEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
KYSSQNYQRSAHRKLTNATDDTNKILKIVVELSEEIYNPEYKFSKAGVLMQDLTNSEYLQ
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHCCCHHHHH
QSVINYKSQKDLKKSANLMKTIDLLNKRFNNNAITWAITKNPQSWKMNNNFLSRSSTTDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEECCCCCCCH
EQIPTIVK
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2989817; 2989816; 8905232; 9278503; 1320188 [H]