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The map label for this gene is ureC [H]

Identifier: 123968428

GI number: 123968428

Start: 768414

End: 770123

Strand: Direct

Name: ureC [H]

Synonym: A9601_08951

Alternate gene names: 123968428

Gene position: 768414-770123 (Clockwise)

Preceding gene: 123968427

Following gene: 123968430

Centisome position: 46.02

GC content: 36.9

Gene sequence:

>1710_bases
ATGTCTTACAAAATTGATAGAAAAACTTATGCTCAAACTTACGGACCTACTACAGGAGATAGAGTAAGGCTTGCTGATAC
CGAACTGTTTATAGAAGTAGAAAAGGATTTAACTACATACGGAGATGAAGTTAAATTTGGTGGAGGTAAAGTTATTCGAG
ATGGGATGGGACAGTCTCAAGTAAGAAGAGCTGATGGAGCTGTAGATACCGTAATAACTAATGCTTTGATCGTAGATTGG
TGGGGAATTATTAAGGCTGATGTGGGTATAAAAGATGGAATGATTTTTGAAATTGGTAAGGCTGGCAATCCAGATATCCA
GGATAATGTTGATATTGTTATTGGTGCATCAACAGAAGTAATAGCTGGAGAGGGGCATATTCTTACTGCAGGTTCAATAG
ATACCCATATTCACTTTATCTGTCCCCAACAAATTGAGACAGCACTATCCTCTGGAATTACAACCATGTTGGGAGGAGGA
ACAGGACCTGCAACTGGCACAAATGCGACTACTTGTACTCCTGGTTCTTTTCATATTTCAAGAATGCTTCAATCTGCAGA
AGCATTTCCTATGAATTTAGGTTTTTTTGGAAAAGGAAACTCAACAAACGAGATCAATCTTATTGATCAGGTTGAGGCTG
GTGCTTGTGGTTTGAAGCTTCATGAAGATTGGGGGACCACCCCTTCTACAATAAATTCTTGTCTAAATGTTGCAGATAAA
TTTGACGTACAAGTATGTATTCATACTGATACTTTGAATGAGGCAGGCTTTGTTGAAGATACCATCAACGCTATTGCAGG
AAGAACTATTCATACTTTTCATACCGAAGGAGCAGGTGGAGGTCATGCTCCAGACATTATAAAAATCTGTGGAGAAAAAA
ATGTTCTTCCTAGTAGTACAAATCCAACAAGACCTTATACAAGAAACACATTAGAAGAACATCTTGACATGTTAATGGTT
TGTCATCATTTAGATTCTAAAATCCCAGAAGACATTGCATTTGCTGAGTCAAGGATAAGAAGAGAGACTATTGCAGCTGA
GGATATCTTGCATGATTTAGGTGCCTTTTCAATAATTGCTAGTGATTCTCAAGCTATGGGAAGAGTTGGCGAAGTAATTA
CAAGAACTTTTCAAACCGCACATAAAATGAAAGTCCAAAGGGGGCCGCTATCGCAGGATTCTGATAGAAACGATAACTAT
AGAGTGAAGAGATATATTTCTAAAGTCACAATTAATCCTGCAATAGCTCATGGTATTGATAAACATGTTGGGTCTATAGA
AAAGGGTAAAATTGCAGATTTGGTATTGTGGAAACCTTCCTTTTTTGCGGTGAAGCCTGAATTAGTTGTTAAAGGAGGAT
CTATAGTTTGGTCCCAAATGGGTGATGCAAATGCTTCAATTCCTACTCCAGGTCCCGTACATGGTCGGCCTATGTTTGCA
AGTTTCGGCCAATCTCTAATTAAGAGTTCTTTTACCTTTCTAAGTAAAAATTCAATTGAACAAAATATTCCAAATAAATT
AGGCTTACAAAAAAAATGTATTGCCGTAGAAAATACAAGAAATATCAATAAATCAAACTTAAAACTTAATACTAAACTAC
CAAATATTTCAGTTGATCCTCAAACTTATGAAGTTTTTTCTGATGGAGAACTTCTTACTTGTGAACCACTTGATGAAGTC
CCAATGGCTCAGAGGTATTTTTTGCTTTAG

Upstream 100 bases:

>100_bases
CCGGGGGATACAACAGATGTCAAATTAGTTCCATTTTCAGGTTTAAGAAATGCATATGGTTTTAATTCATTAGTTAATGG
TTCTTTAAATAGTTAGAATT

Downstream 100 bases:

>100_bases
AAGTTTTTAATTAATTCTTTTTCACTTATCTTTATGTCTTTTGACCCCGCAATCGCTAAATCTTCTTGAAGTTTGTTCTC
ACAAGATAGAACCCTTGACC

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSYKIDRKTYAQTYGPTTGDRVRLADTELFIEVEKDLTTYGDEVKFGGGKVIRDGMGQSQVRRADGAVDTVITNALIVDW
WGIIKADVGIKDGMIFEIGKAGNPDIQDNVDIVIGASTEVIAGEGHILTAGSIDTHIHFICPQQIETALSSGITTMLGGG
TGPATGTNATTCTPGSFHISRMLQSAEAFPMNLGFFGKGNSTNEINLIDQVEAGACGLKLHEDWGTTPSTINSCLNVADK
FDVQVCIHTDTLNEAGFVEDTINAIAGRTIHTFHTEGAGGGHAPDIIKICGEKNVLPSSTNPTRPYTRNTLEEHLDMLMV
CHHLDSKIPEDIAFAESRIRRETIAAEDILHDLGAFSIIASDSQAMGRVGEVITRTFQTAHKMKVQRGPLSQDSDRNDNY
RVKRYISKVTINPAIAHGIDKHVGSIEKGKIADLVLWKPSFFAVKPELVVKGGSIVWSQMGDANASIPTPGPVHGRPMFA
SFGQSLIKSSFTFLSKNSIEQNIPNKLGLQKKCIAVENTRNINKSNLKLNTKLPNISVDPQTYEVFSDGELLTCEPLDEV
PMAQRYFLL

Sequences:

>Translated_569_residues
MSYKIDRKTYAQTYGPTTGDRVRLADTELFIEVEKDLTTYGDEVKFGGGKVIRDGMGQSQVRRADGAVDTVITNALIVDW
WGIIKADVGIKDGMIFEIGKAGNPDIQDNVDIVIGASTEVIAGEGHILTAGSIDTHIHFICPQQIETALSSGITTMLGGG
TGPATGTNATTCTPGSFHISRMLQSAEAFPMNLGFFGKGNSTNEINLIDQVEAGACGLKLHEDWGTTPSTINSCLNVADK
FDVQVCIHTDTLNEAGFVEDTINAIAGRTIHTFHTEGAGGGHAPDIIKICGEKNVLPSSTNPTRPYTRNTLEEHLDMLMV
CHHLDSKIPEDIAFAESRIRRETIAAEDILHDLGAFSIIASDSQAMGRVGEVITRTFQTAHKMKVQRGPLSQDSDRNDNY
RVKRYISKVTINPAIAHGIDKHVGSIEKGKIADLVLWKPSFFAVKPELVVKGGSIVWSQMGDANASIPTPGPVHGRPMFA
SFGQSLIKSSFTFLSKNSIEQNIPNKLGLQKKCIAVENTRNINKSNLKLNTKLPNISVDPQTYEVFSDGELLTCEPLDEV
PMAQRYFLL
>Mature_568_residues
SYKIDRKTYAQTYGPTTGDRVRLADTELFIEVEKDLTTYGDEVKFGGGKVIRDGMGQSQVRRADGAVDTVITNALIVDWW
GIIKADVGIKDGMIFEIGKAGNPDIQDNVDIVIGASTEVIAGEGHILTAGSIDTHIHFICPQQIETALSSGITTMLGGGT
GPATGTNATTCTPGSFHISRMLQSAEAFPMNLGFFGKGNSTNEINLIDQVEAGACGLKLHEDWGTTPSTINSCLNVADKF
DVQVCIHTDTLNEAGFVEDTINAIAGRTIHTFHTEGAGGGHAPDIIKICGEKNVLPSSTNPTRPYTRNTLEEHLDMLMVC
HHLDSKIPEDIAFAESRIRRETIAAEDILHDLGAFSIIASDSQAMGRVGEVITRTFQTAHKMKVQRGPLSQDSDRNDNYR
VKRYISKVTINPAIAHGIDKHVGSIEKGKIADLVLWKPSFFAVKPELVVKGGSIVWSQMGDANASIPTPGPVHGRPMFAS
FGQSLIKSSFTFLSKNSIEQNIPNKLGLQKKCIAVENTRNINKSNLKLNTKLPNISVDPQTYEVFSDGELLTCEPLDEVP
MAQRYFLL

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 61784; Mature: 61653

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKIDRKTYAQTYGPTTGDRVRLADTELFIEVEKDLTTYGDEVKFGGGKVIRDGMGQSQ
CCEECCCHHHHHHCCCCCCCEEEEECCEEEEEECCHHHCCCCEEEECCCEEEECCCCHHH
VRRADGAVDTVITNALIVDWWGIIKADVGIKDGMIFEIGKAGNPDIQDNVDIVIGASTEV
HHHHCCHHHHHHHHHHHEEHHHHEEECCCCCCCEEEEECCCCCCCCCCCCCEEEECCCEE
IAGEGHILTAGSIDTHIHFICPQQIETALSSGITTMLGGGTGPATGTNATTCTPGSFHIS
EECCCCEEEECCCCCEEEEECHHHHHHHHHCCCCEEECCCCCCCCCCCCCEECCCHHHHH
RMLQSAEAFPMNLGFFGKGNSTNEINLIDQVEAGACGLKLHEDWGTTPSTINSCLNVADK
HHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHCC
FDVQVCIHTDTLNEAGFVEDTINAIAGRTIHTFHTEGAGGGHAPDIIKICGEKNVLPSST
CCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCC
NPTRPYTRNTLEEHLDMLMVCHHLDSKIPEDIAFAESRIRRETIAAEDILHDLGAFSIIA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
SDSQAMGRVGEVITRTFQTAHKMKVQRGPLSQDSDRNDNYRVKRYISKVTINPAIAHGID
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
KHVGSIEKGKIADLVLWKPSFFAVKPELVVKGGSIVWSQMGDANASIPTPGPVHGRPMFA
HHHCCCCCCCEEEEEEECCCEEEECCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCHHH
SFGQSLIKSSFTFLSKNSIEQNIPNKLGLQKKCIAVENTRNINKSNLKLNTKLPNISVDP
HHHHHHHHHHHHHHHHCCHHHCCCHHHCCCCEEEEECCCCCCCCCCEEEEECCCCCEECC
QTYEVFSDGELLTCEPLDEVPMAQRYFLL
CEEEEECCCCEEEECCCCCCCCCHHHCCC
>Mature Secondary Structure 
SYKIDRKTYAQTYGPTTGDRVRLADTELFIEVEKDLTTYGDEVKFGGGKVIRDGMGQSQ
CEECCCHHHHHHCCCCCCCEEEEECCEEEEEECCHHHCCCCEEEECCCEEEECCCCHHH
VRRADGAVDTVITNALIVDWWGIIKADVGIKDGMIFEIGKAGNPDIQDNVDIVIGASTEV
HHHHCCHHHHHHHHHHHEEHHHHEEECCCCCCCEEEEECCCCCCCCCCCCCEEEECCCEE
IAGEGHILTAGSIDTHIHFICPQQIETALSSGITTMLGGGTGPATGTNATTCTPGSFHIS
EECCCCEEEECCCCCEEEEECHHHHHHHHHCCCCEEECCCCCCCCCCCCCEECCCHHHHH
RMLQSAEAFPMNLGFFGKGNSTNEINLIDQVEAGACGLKLHEDWGTTPSTINSCLNVADK
HHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHCC
FDVQVCIHTDTLNEAGFVEDTINAIAGRTIHTFHTEGAGGGHAPDIIKICGEKNVLPSST
CCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCC
NPTRPYTRNTLEEHLDMLMVCHHLDSKIPEDIAFAESRIRRETIAAEDILHDLGAFSIIA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
SDSQAMGRVGEVITRTFQTAHKMKVQRGPLSQDSDRNDNYRVKRYISKVTINPAIAHGID
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
KHVGSIEKGKIADLVLWKPSFFAVKPELVVKGGSIVWSQMGDANASIPTPGPVHGRPMFA
HHHCCCCCCCEEEEEEECCCEEEECCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCHHH
SFGQSLIKSSFTFLSKNSIEQNIPNKLGLQKKCIAVENTRNINKSNLKLNTKLPNISVDP
HHHHHHHHHHHHHHHHCCHHHCCCHHHCCCCEEEEECCCCCCCCCCEEEEECCCCCEECC
QTYEVFSDGELLTCEPLDEVPMAQRYFLL
CEEEEECCCCEEEECCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA