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The map label for this gene is livH [H]

Identifier: 123968420

GI number: 123968420

Start: 762396

End: 763550

Strand: Reverse

Name: livH [H]

Synonym: A9601_08871

Alternate gene names: 123968420

Gene position: 763550-762396 (Counterclockwise)

Preceding gene: 123968421

Following gene: 123968419

Centisome position: 45.72

GC content: 35.84

Gene sequence:

>1155_bases
TTGGAGTTACTTCTCGATAGTCTTTTTAATGGTGTTGCAATCGGATCTGTACTACTTGTTGCAGCATTAGGTCTAGCAAT
TGTTTTTGGTCTTATGGGTGTAATAAATCTTGCCCATGGAGAGCTTATGATGCTTGGGGCTTACACAACATACGTAACAC
AATTAATTTTCAAATTACCTATATTAAAACCTTTCTACAATTCGTACATAATAGTTTCTATTTTCCTTGCTTTTATTGTT
AGTGGAGTAGTTGGCATTCTTCTGGAAAAAACCATAATAAGAAAGCTTTATGGAAGTCCACTAGAAACACTTCTAGCAAC
TTGGGGCGTAAGCTTAATTCTTCAACAATTTGTCAGAAGTGTACCTTTAGCTTATGGGACCGGTCTGGTTATAAGTCTGT
TAATTGGGTTATTCTTACCAACAACATTCCCTTCAAAAATAAAAGAATCAATAAATTTCAAATATTTTAAATTTAGTTCT
TGGATATTTGCTGCTTTAACTGGGGTCCTGACAGGTGGTGTAATCTCATCCTCTGTCAGCAAACTTAGTAGAGCAAGCGC
TAGAAATGTTGATGTAACAGCACCCTCATGGATGAGAGGTCAAGTTGAAATCATTGGAACTGCATTTCCTAAGACAAGAT
TAATGATAATTGTCATAACTCTAATCTCTGTAATAGCAATAACATTATTTCTTAATCAAAGTGCCTGGGGGATGCGTATA
AGAGCAGTTACTCAGAACCGACAAATGAGTGATTGTCTTGGTATATCTACTGAAAAAGTGGATATAATTACTTTTGGAAT
TGGATCTGGCTTAGCAGGAGTTGCTGGTGTAGCAGTATCTCTTTTAGGTTCTGTAGGACCAAATGTTGGCGGAAACTACA
TAGTTGGTTGTTTTATGGTTGTAGTGCTGGGAGGTGTAGGAAATTTATTAGGAACAGTACTTGCTTCATTTGGAATAGGA
ATAATGACTGATTTAATCGGAGCCGGAAGGCTCTTATCAATATGGCCAGATATGCCTTTACCTTTATCAAACACAATTAA
CTTTTTTGCGACCACAAGTATGGCAAGAGTAATGATATTTGCACTAATTGTTATATTCTTACAATTTAAACCTACAGGTT
TATTTCCTCAAAAAGGAAGGATGGTTGAAAACTAA

Upstream 100 bases:

>100_bases
GAAAAGTATAAGCTTTAAACTTATTAAAACCTATACTTCAAAATAAAAGGAGGTTAACACCTCCTTTTATTTTATATAAT
CAAATTTTTCTTTTTTAAAA

Downstream 100 bases:

>100_bases
TGTCCTTAAGTAAAATTAAATTTGATAAAAAAATAGTATTATCATTTTGGATAATATTAATAGCCTTAATTATTGCAGCA
CCAACTATACTCCCTGTATT

Product: putative urea ABC transporter

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MELLLDSLFNGVAIGSVLLVAALGLAIVFGLMGVINLAHGELMMLGAYTTYVTQLIFKLPILKPFYNSYIIVSIFLAFIV
SGVVGILLEKTIIRKLYGSPLETLLATWGVSLILQQFVRSVPLAYGTGLVISLLIGLFLPTTFPSKIKESINFKYFKFSS
WIFAALTGVLTGGVISSSVSKLSRASARNVDVTAPSWMRGQVEIIGTAFPKTRLMIIVITLISVIAITLFLNQSAWGMRI
RAVTQNRQMSDCLGISTEKVDIITFGIGSGLAGVAGVAVSLLGSVGPNVGGNYIVGCFMVVVLGGVGNLLGTVLASFGIG
IMTDLIGAGRLLSIWPDMPLPLSNTINFFATTSMARVMIFALIVIFLQFKPTGLFPQKGRMVEN

Sequences:

>Translated_384_residues
MELLLDSLFNGVAIGSVLLVAALGLAIVFGLMGVINLAHGELMMLGAYTTYVTQLIFKLPILKPFYNSYIIVSIFLAFIV
SGVVGILLEKTIIRKLYGSPLETLLATWGVSLILQQFVRSVPLAYGTGLVISLLIGLFLPTTFPSKIKESINFKYFKFSS
WIFAALTGVLTGGVISSSVSKLSRASARNVDVTAPSWMRGQVEIIGTAFPKTRLMIIVITLISVIAITLFLNQSAWGMRI
RAVTQNRQMSDCLGISTEKVDIITFGIGSGLAGVAGVAVSLLGSVGPNVGGNYIVGCFMVVVLGGVGNLLGTVLASFGIG
IMTDLIGAGRLLSIWPDMPLPLSNTINFFATTSMARVMIFALIVIFLQFKPTGLFPQKGRMVEN
>Mature_384_residues
MELLLDSLFNGVAIGSVLLVAALGLAIVFGLMGVINLAHGELMMLGAYTTYVTQLIFKLPILKPFYNSYIIVSIFLAFIV
SGVVGILLEKTIIRKLYGSPLETLLATWGVSLILQQFVRSVPLAYGTGLVISLLIGLFLPTTFPSKIKESINFKYFKFSS
WIFAALTGVLTGGVISSSVSKLSRASARNVDVTAPSWMRGQVEIIGTAFPKTRLMIIVITLISVIAITLFLNQSAWGMRI
RAVTQNRQMSDCLGISTEKVDIITFGIGSGLAGVAGVAVSLLGSVGPNVGGNYIVGCFMVVVLGGVGNLLGTVLASFGIG
IMTDLIGAGRLLSIWPDMPLPLSNTINFFATTSMARVMIFALIVIFLQFKPTGLFPQKGRMVEN

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=376, Percent_Identity=25.531914893617, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 41046; Mature: 41046

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLLDSLFNGVAIGSVLLVAALGLAIVFGLMGVINLAHGELMMLGAYTTYVTQLIFKLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
ILKPFYNSYIIVSIFLAFIVSGVVGILLEKTIIRKLYGSPLETLLATWGVSLILQQFVRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VPLAYGTGLVISLLIGLFLPTTFPSKIKESINFKYFKFSSWIFAALTGVLTGGVISSSVS
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
KLSRASARNVDVTAPSWMRGQVEIIGTAFPKTRLMIIVITLISVIAITLFLNQSAWGMRI
HHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
RAVTQNRQMSDCLGISTEKVDIITFGIGSGLAGVAGVAVSLLGSVGPNVGGNYIVGCFMV
EEECCCCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VVLGGVGNLLGTVLASFGIGIMTDLIGAGRLLSIWPDMPLPLSNTINFFATTSMARVMIF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
ALIVIFLQFKPTGLFPQKGRMVEN
HHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MELLLDSLFNGVAIGSVLLVAALGLAIVFGLMGVINLAHGELMMLGAYTTYVTQLIFKLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
ILKPFYNSYIIVSIFLAFIVSGVVGILLEKTIIRKLYGSPLETLLATWGVSLILQQFVRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VPLAYGTGLVISLLIGLFLPTTFPSKIKESINFKYFKFSSWIFAALTGVLTGGVISSSVS
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
KLSRASARNVDVTAPSWMRGQVEIIGTAFPKTRLMIIVITLISVIAITLFLNQSAWGMRI
HHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
RAVTQNRQMSDCLGISTEKVDIITFGIGSGLAGVAGVAVSLLGSVGPNVGGNYIVGCFMV
EEECCCCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VVLGGVGNLLGTVLASFGIGIMTDLIGAGRLLSIWPDMPLPLSNTINFFATTSMARVMIF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
ALIVIFLQFKPTGLFPQKGRMVEN
HHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]