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The map label for this gene is pqqL [C]

Identifier: 123968342

GI number: 123968342

Start: 694842

End: 696092

Strand: Reverse

Name: pqqL [C]

Synonym: A9601_08071

Alternate gene names: 123968342

Gene position: 696092-694842 (Counterclockwise)

Preceding gene: 123968353

Following gene: 123968341

Centisome position: 41.69

GC content: 29.98

Gene sequence:

>1251_bases
ATGAAAGTAGGAGATGTTAACTACTACACCCATTCAAGCAAAACTAGATGTGTTTTTGTGGACAATAAAGAATTGCCGCT
TATAAGCATTGATATTTGGTGCAAAGCAGGTTCTTCATTTGAGGATGTTGATAAAAATGGCACTGCTCATTTTCTAGAAC
ATATGATTTTTAAAGGATCTAACAAAATAATGCCAGGTGAGTTTGACCATAAAATTGAATCACTAGGCGGAGTAAGTAAC
GCTTCAACTGGTTATGATGATGTACATTACCATGTCTTAGTTCCACCCAATAACTTTAAAGAATCACTTGCTCTTTTGAC
AAATATAGTCGTTGCTCCAGTTTTTAATCCTGATGAGTTTATAAAAGAAAAAGGGGTAGTTATTGATGAAATAAAACAAC
AAAATGATCAGCCTGAAGAGAGACTATTTAATTATTTTTTAAAAAGGGTTTGGTTAAGTCCTAATTATGCCAATTCGATC
TTGGGAACTGAACATAGCATTAAAAACTTAGAGATAAATGACCTTACGAAATTTCATAGCAAACATTACACTACCGAAAA
AATTTGTATCGCAATTGCGGGGAATCTCTCCGAAGAAATTTATAAAATTTTTGAAAAAAGTGATCTATCTGGTATAAAAG
AAAGTCCAAATTTAATAAATCTAAAAAATAAACCTTCTTTAAAAATAAGGAATGGTAGAGAGTCAGTTAAGTTTGAAAAT
TTAGAGTTTTCAAGAATATTTATGGCTTGGTTTATACCAAACCTAAATGATCAAAAAAATATTATTGGACTTGAGATATT
AGCATCCATACTCTCTGTTGGAAGAAACAGCAGATTAGTTAAAATTTTAAAAGAAGATAATAATCTTGTTGAATCGATAT
ATGTAGATGTAAATGCTGGAGAATTAGGAGGATTATTTATAATGGAAGCAAGTTGTGAGTCCAAAGATATTGATTTAGTA
GAAAAGCAAATTAATAAAACAATAGATGAGATATCAAATTGTAAACTCTTGGCTTTGGATGAAATAAAAAAAGCAATAAA
TATTGTTAAAAGTAATTATATCTTTAATTTAGAGACATCTACACAACTCACTTCATTCTATGGGAATGAACTTCTTTGGG
GGAGAAAATCTTCAATAAATAGTATAGAGAGTCATTTAAAATATTGGAATAACTTGGAAAATTTCAAAGAGATCACAGAA
TATATCCGTGGAGAGAAATTTACATTAGTTGCATCCCCTGGTAAATGTTAA

Upstream 100 bases:

>100_bases
AATAAATCCAAAATAAGAGGGTCAGTTAATTTTGATTTAGTTAAAGATTCAGACAACAAGGCTAAAAAGTACCAAAATAG
AATTTAAAGAGAGAACCGAA

Downstream 100 bases:

>100_bases
AGAGATATTTTTTAAATAATAAAAAAAGAAATTTTTCAATTGCTTCAATTTGGATTAAAGGGGGGAGTGATATGGATAGT
ACTGGCAAAAAAGGTATTAA

Product: Zn-dependent peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MKVGDVNYYTHSSKTRCVFVDNKELPLISIDIWCKAGSSFEDVDKNGTAHFLEHMIFKGSNKIMPGEFDHKIESLGGVSN
ASTGYDDVHYHVLVPPNNFKESLALLTNIVVAPVFNPDEFIKEKGVVIDEIKQQNDQPEERLFNYFLKRVWLSPNYANSI
LGTEHSIKNLEINDLTKFHSKHYTTEKICIAIAGNLSEEIYKIFEKSDLSGIKESPNLINLKNKPSLKIRNGRESVKFEN
LEFSRIFMAWFIPNLNDQKNIIGLEILASILSVGRNSRLVKILKEDNNLVESIYVDVNAGELGGLFIMEASCESKDIDLV
EKQINKTIDEISNCKLLALDEIKKAINIVKSNYIFNLETSTQLTSFYGNELLWGRKSSINSIESHLKYWNNLENFKEITE
YIRGEKFTLVASPGKC

Sequences:

>Translated_416_residues
MKVGDVNYYTHSSKTRCVFVDNKELPLISIDIWCKAGSSFEDVDKNGTAHFLEHMIFKGSNKIMPGEFDHKIESLGGVSN
ASTGYDDVHYHVLVPPNNFKESLALLTNIVVAPVFNPDEFIKEKGVVIDEIKQQNDQPEERLFNYFLKRVWLSPNYANSI
LGTEHSIKNLEINDLTKFHSKHYTTEKICIAIAGNLSEEIYKIFEKSDLSGIKESPNLINLKNKPSLKIRNGRESVKFEN
LEFSRIFMAWFIPNLNDQKNIIGLEILASILSVGRNSRLVKILKEDNNLVESIYVDVNAGELGGLFIMEASCESKDIDLV
EKQINKTIDEISNCKLLALDEIKKAINIVKSNYIFNLETSTQLTSFYGNELLWGRKSSINSIESHLKYWNNLENFKEITE
YIRGEKFTLVASPGKC
>Mature_416_residues
MKVGDVNYYTHSSKTRCVFVDNKELPLISIDIWCKAGSSFEDVDKNGTAHFLEHMIFKGSNKIMPGEFDHKIESLGGVSN
ASTGYDDVHYHVLVPPNNFKESLALLTNIVVAPVFNPDEFIKEKGVVIDEIKQQNDQPEERLFNYFLKRVWLSPNYANSI
LGTEHSIKNLEINDLTKFHSKHYTTEKICIAIAGNLSEEIYKIFEKSDLSGIKESPNLINLKNKPSLKIRNGRESVKFEN
LEFSRIFMAWFIPNLNDQKNIIGLEILASILSVGRNSRLVKILKEDNNLVESIYVDVNAGELGGLFIMEASCESKDIDLV
EKQINKTIDEISNCKLLALDEIKKAINIVKSNYIFNLETSTQLTSFYGNELLWGRKSSINSIESHLKYWNNLENFKEITE
YIRGEKFTLVASPGKC

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=401, Percent_Identity=25.6857855361596, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI46593007, Length=392, Percent_Identity=21.6836734693878, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71999683, Length=389, Percent_Identity=22.879177377892, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17553678, Length=388, Percent_Identity=21.3917525773196, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323192, Length=362, Percent_Identity=22.6519337016575, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357875, Length=373, Percent_Identity=22.2520107238606, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24646943, Length=373, Percent_Identity=22.2520107238606, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24641429, Length=254, Percent_Identity=24.4094488188976, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24667786, Length=176, Percent_Identity=26.1363636363636, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47349; Mature: 47349

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGDVNYYTHSSKTRCVFVDNKELPLISIDIWCKAGSSFEDVDKNGTAHFLEHMIFKGS
CCCCCCEEEECCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHCCCCHHHHHHHHHHCCC
NKIMPGEFDHKIESLGGVSNASTGYDDVHYHVLVPPNNFKESLALLTNIVVAPVFNPDEF
CCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHEECCCHHHH
IKEKGVVIDEIKQQNDQPEERLFNYFLKRVWLSPNYANSILGTEHSIKNLEINDLTKFHS
HHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHH
KHYTTEKICIAIAGNLSEEIYKIFEKSDLSGIKESPNLINLKNKPSLKIRNGRESVKFEN
HCCCHHEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCEECC
LEFSRIFMAWFIPNLNDQKNIIGLEILASILSVGRNSRLVKILKEDNNLVESIYVDVNAG
CHHHHEEEEHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEEECCC
ELGGLFIMEASCESKDIDLVEKQINKTIDEISNCKLLALDEIKKAINIVKSNYIFNLETS
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHCCEEEEECCC
TQLTSFYGNELLWGRKSSINSIESHLKYWNNLENFKEITEYIRGEKFTLVASPGKC
HHHHHHHCCCEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCEEEEEECCCCC
>Mature Secondary Structure
MKVGDVNYYTHSSKTRCVFVDNKELPLISIDIWCKAGSSFEDVDKNGTAHFLEHMIFKGS
CCCCCCEEEECCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHCCCCHHHHHHHHHHCCC
NKIMPGEFDHKIESLGGVSNASTGYDDVHYHVLVPPNNFKESLALLTNIVVAPVFNPDEF
CCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHEECCCHHHH
IKEKGVVIDEIKQQNDQPEERLFNYFLKRVWLSPNYANSILGTEHSIKNLEINDLTKFHS
HHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHH
KHYTTEKICIAIAGNLSEEIYKIFEKSDLSGIKESPNLINLKNKPSLKIRNGRESVKFEN
HCCCHHEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCEECC
LEFSRIFMAWFIPNLNDQKNIIGLEILASILSVGRNSRLVKILKEDNNLVESIYVDVNAG
CHHHHEEEEHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEEECCC
ELGGLFIMEASCESKDIDLVEKQINKTIDEISNCKLLALDEIKKAINIVKSNYIFNLETS
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHCCEEEEECCC
TQLTSFYGNELLWGRKSSINSIESHLKYWNNLENFKEITEYIRGEKFTLVASPGKC
HHHHHHHCCCEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]