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The map label for this gene is csgA [H]

Identifier: 123968292

GI number: 123968292

Start: 665247

End: 665912

Strand: Direct

Name: csgA [H]

Synonym: A9601_07571

Alternate gene names: 123968292

Gene position: 665247-665912 (Clockwise)

Preceding gene: 123968282

Following gene: 123968299

Centisome position: 39.84

GC content: 32.58

Gene sequence:

>666_bases
ATGTCGACTTATCTAATTACAGGATCAAATAGGGGTATTGGATTAGAACTATGTAGACAAATTCATAAGAGGGGAGATAA
TGTAATTGCAACGTGTAGGAAAGCTTCAAAAGAACTTAGAGATTTAGGAGTGAGAATTGAAGAGAATATAGAAATTTCTT
CTGATGAGTCGATAACAAATTTGTGTAAAAAACTATCCGGAGTTAATTTAGATTGCTTTATTCATAATGCAGGAATTTAT
GAATTTAATTCTTTCGAAAACTTAGATAAAAAAAGTATTTTGCGGCAATTTGAAGTCAATGCATTGAGCCCAATATGTAT
GACTCAATCACTTAAACATTTTTTAAAAAGATCTTCTAAAGTTGCTTTTATCACGAGTAGAATGGGATCTATTGAAGATA
ATACATCAGGAAGTTCTTATGGTTACAGAATGTCTAAGGTTGCCTTGTCCATGGCAGCAAAATCACTTTCCATAGATTTA
TCAAGGGAAGATATTTATGTAGCTATTTTGCATCCTGGGTTAGTGAGTACAAGAATGACTGGCTTTACAAGAAATGGAAT
AAGTCCTGAAGAATCAGCAAATGGCCTTTTAAAACGTATTGATTCTTTAAATAAAAATAACTCGGGTACTTTTTGGCATG
CTAACGGAGAAGTTTTGCCTTGGTAA

Upstream 100 bases:

>100_bases
CTTAAAAAATCTAATAAGGAATTTTATAAATTTTTTCTTGTTCTAGTTCGTTTTCTTTTATATTTGGATTTAGATTAATT
TTTTATTTTTTAGTTTAGAG

Downstream 100 bases:

>100_bases
TATAAATATATTTATATTGAAGAGATTTATATCTTTAATTTGTTAAAAAATTTTTAAATTTTTAACGAATTTCTTTCCTT
GTTTAATTCTTTTGGTTATC

Product: short-chain dehydrogenase/reductase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSTYLITGSNRGIGLELCRQIHKRGDNVIATCRKASKELRDLGVRIEENIEISSDESITNLCKKLSGVNLDCFIHNAGIY
EFNSFENLDKKSILRQFEVNALSPICMTQSLKHFLKRSSKVAFITSRMGSIEDNTSGSSYGYRMSKVALSMAAKSLSIDL
SREDIYVAILHPGLVSTRMTGFTRNGISPEESANGLLKRIDSLNKNNSGTFWHANGEVLPW

Sequences:

>Translated_221_residues
MSTYLITGSNRGIGLELCRQIHKRGDNVIATCRKASKELRDLGVRIEENIEISSDESITNLCKKLSGVNLDCFIHNAGIY
EFNSFENLDKKSILRQFEVNALSPICMTQSLKHFLKRSSKVAFITSRMGSIEDNTSGSSYGYRMSKVALSMAAKSLSIDL
SREDIYVAILHPGLVSTRMTGFTRNGISPEESANGLLKRIDSLNKNNSGTFWHANGEVLPW
>Mature_220_residues
STYLITGSNRGIGLELCRQIHKRGDNVIATCRKASKELRDLGVRIEENIEISSDESITNLCKKLSGVNLDCFIHNAGIYE
FNSFENLDKKSILRQFEVNALSPICMTQSLKHFLKRSSKVAFITSRMGSIEDNTSGSSYGYRMSKVALSMAAKSLSIDLS
REDIYVAILHPGLVSTRMTGFTRNGISPEESANGLLKRIDSLNKNNSGTFWHANGEVLPW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Escherichia coli, GI1786701, Length=185, Percent_Identity=25.9459459459459, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17558996, Length=248, Percent_Identity=30.6451612903226, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17559964, Length=248, Percent_Identity=35.0806451612903, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17558994, Length=242, Percent_Identity=32.2314049586777, Blast_Score=93, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17559962, Length=247, Percent_Identity=34.0080971659919, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193207563, Length=242, Percent_Identity=29.3388429752066, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI72001658, Length=244, Percent_Identity=32.7868852459016, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17542178, Length=239, Percent_Identity=31.7991631799163, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17558992, Length=244, Percent_Identity=31.9672131147541, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17541382, Length=251, Percent_Identity=30.2788844621514, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17558990, Length=247, Percent_Identity=27.5303643724696, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17532177, Length=238, Percent_Identity=31.0924369747899, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322779, Length=245, Percent_Identity=30.6122448979592, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24640547, Length=249, Percent_Identity=30.1204819277108, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24643142, Length=180, Percent_Identity=30, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24572; Mature: 24441

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTYLITGSNRGIGLELCRQIHKRGDNVIATCRKASKELRDLGVRIEENIEISSDESITN
CCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECCEEECCCHHHHH
LCKKLSGVNLDCFIHNAGIYEFNSFENLDKKSILRQFEVNALSPICMTQSLKHFLKRSSK
HHHHHCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
VAFITSRMGSIEDNTSGSSYGYRMSKVALSMAAKSLSIDLSREDIYVAILHPGLVSTRMT
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCHHHHHHC
GFTRNGISPEESANGLLKRIDSLNKNNSGTFWHANGEVLPW
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
STYLITGSNRGIGLELCRQIHKRGDNVIATCRKASKELRDLGVRIEENIEISSDESITN
CEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECCEEECCCHHHHH
LCKKLSGVNLDCFIHNAGIYEFNSFENLDKKSILRQFEVNALSPICMTQSLKHFLKRSSK
HHHHHCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
VAFITSRMGSIEDNTSGSSYGYRMSKVALSMAAKSLSIDLSREDIYVAILHPGLVSTRMT
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCHHHHHHC
GFTRNGISPEESANGLLKRIDSLNKNNSGTFWHANGEVLPW
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]