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The map label for this gene is dnaA [H]

Identifier: 123968156

GI number: 123968156

Start: 541765

End: 543159

Strand: Direct

Name: dnaA [H]

Synonym: A9601_06211

Alternate gene names: 123968156

Gene position: 541765-543159 (Clockwise)

Preceding gene: 123968153

Following gene: 123968158

Centisome position: 32.44

GC content: 34.55

Gene sequence:

>1395_bases
TTGCAAGCAACTAATCCTATTTGGGCGGAAGTTCAACAATCACTCCAAAAAACTTTAAGTAAGCCTTCATTTGAGACATG
GATAAGGCCTGCTAAGTTTAATTGTTTTGAAAATGGCTTATTAACTTTAATCGCCCCAAATACATTTTCTAGTGATTGGT
TGAGAAAGAATTATTGTGAAACTATTGAAAAAGCTGCGAAGGAAATCTGCGGTCATGATGTAAAAGTTGTTTTTAAATCT
GAAACGAATACCAGCAGCGATTTATCAAATGAAGATAAAGCTAACGAAAAGAATGTTCATCATAAAACAAGATCTTTTTC
TAGTAATAACCAAAATAATTCTTCAAAAAATCAATTCAAAAATCCTAATGGTTTAAATTTACGCTACGTCTTTAAAAGAT
TTGTTGTAGGTCCAAATAGTAGGTTGGCTCATGCCGCAGCTTTAGCCGTTGCCGAATCTCCTGGGAGAGAATTCAATCCA
TTATTTATTTGTGGAGGAGTAGGCCTTGGTAAGACTCATTTAATGCAAGCAATAGGTCATTATCGAGTAGAAATAGATCC
AGAAGCAAAAGTTAAATATGTATCTACAGAGACTTTTACAAATGATGTTATTAGTGGTATTCGAAGAGATGGAATGACAG
CTATACGAGATAAATATAGAAATGTAGATTTGATTTTAATAGATGATATACAGTTCTTAGAAGGCAAAGAGTATACACAG
GAAGAATTCTTTCATACTTTTAACGCACTTCACGAATCAGGAAGTCAAATAGTTATTGCAAGTGACAGACCACCAAATCA
GTTGTCGGGAATTCAAGAGAGATTAATTTCTAGGTTCTCAATGGGTATGACCGCAGATATTCAACCACCTGACCTTGAGA
CGAGGACAGCCATCCTTCAAAAAAAGGCAGAACAAGAGAGGATGAGTCTTCCAAGAGATTTAATTCAATTTATAGCAGGA
AGATTCACTTCGAATATTCGAGAATTGGAAGGAGCATTTACTAGAGCTGTTGCATTTGCATCAATAACAGGCTTGCCAAT
GACAGTTCAATCAATTGCTCCAATGCTTGATCCTAATAGTGTTGGTGTAGTCGTTACTCCAAAACAAGTTATTAATAAAG
TGTCAGATTTCTTTAAAGTTTCTACTGATGAATTGATCAGTTCAAGTAGGAGAAAACCAGTAAGTCAAGCTAGACAAATA
GGTATGTATCTTATGAGACATGGTACGGATCTAAGCCTACCAAGAATTGGAGATGAGTTTGGGGGTAAGGACCATACAAC
AGTTATGTATGCTATTGAACAAGTTGAAAAAAAGTTATCTATTGATCCAAATATTGCAAGTCAAGTTCAAAAAATAAGAG
ATTTACTTCAAATAGATTCGAGAAAAAATTTATAG

Upstream 100 bases:

>100_bases
CGATACTTTGTTAAATAATTTTAAATTTGTCGTGATCTTGTGATTTGATAATGGCCAATTATTAAATTCCAACTAGATTG
ATAATCTAGAGAATAAAACT

Downstream 100 bases:

>100_bases
TTTTACTTATAACTAGAAATGAAATTTATTGGATCTTGATCATATCGATGCCTAAAAGGTATCTTATCTATTTCATTGAT
GTTACTAAGCGATTCAATTT

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MQATNPIWAEVQQSLQKTLSKPSFETWIRPAKFNCFENGLLTLIAPNTFSSDWLRKNYCETIEKAAKEICGHDVKVVFKS
ETNTSSDLSNEDKANEKNVHHKTRSFSSNNQNNSSKNQFKNPNGLNLRYVFKRFVVGPNSRLAHAAALAVAESPGREFNP
LFICGGVGLGKTHLMQAIGHYRVEIDPEAKVKYVSTETFTNDVISGIRRDGMTAIRDKYRNVDLILIDDIQFLEGKEYTQ
EEFFHTFNALHESGSQIVIASDRPPNQLSGIQERLISRFSMGMTADIQPPDLETRTAILQKKAEQERMSLPRDLIQFIAG
RFTSNIRELEGAFTRAVAFASITGLPMTVQSIAPMLDPNSVGVVVTPKQVINKVSDFFKVSTDELISSSRRKPVSQARQI
GMYLMRHGTDLSLPRIGDEFGGKDHTTVMYAIEQVEKKLSIDPNIASQVQKIRDLLQIDSRKNL

Sequences:

>Translated_464_residues
MQATNPIWAEVQQSLQKTLSKPSFETWIRPAKFNCFENGLLTLIAPNTFSSDWLRKNYCETIEKAAKEICGHDVKVVFKS
ETNTSSDLSNEDKANEKNVHHKTRSFSSNNQNNSSKNQFKNPNGLNLRYVFKRFVVGPNSRLAHAAALAVAESPGREFNP
LFICGGVGLGKTHLMQAIGHYRVEIDPEAKVKYVSTETFTNDVISGIRRDGMTAIRDKYRNVDLILIDDIQFLEGKEYTQ
EEFFHTFNALHESGSQIVIASDRPPNQLSGIQERLISRFSMGMTADIQPPDLETRTAILQKKAEQERMSLPRDLIQFIAG
RFTSNIRELEGAFTRAVAFASITGLPMTVQSIAPMLDPNSVGVVVTPKQVINKVSDFFKVSTDELISSSRRKPVSQARQI
GMYLMRHGTDLSLPRIGDEFGGKDHTTVMYAIEQVEKKLSIDPNIASQVQKIRDLLQIDSRKNL
>Mature_464_residues
MQATNPIWAEVQQSLQKTLSKPSFETWIRPAKFNCFENGLLTLIAPNTFSSDWLRKNYCETIEKAAKEICGHDVKVVFKS
ETNTSSDLSNEDKANEKNVHHKTRSFSSNNQNNSSKNQFKNPNGLNLRYVFKRFVVGPNSRLAHAAALAVAESPGREFNP
LFICGGVGLGKTHLMQAIGHYRVEIDPEAKVKYVSTETFTNDVISGIRRDGMTAIRDKYRNVDLILIDDIQFLEGKEYTQ
EEFFHTFNALHESGSQIVIASDRPPNQLSGIQERLISRFSMGMTADIQPPDLETRTAILQKKAEQERMSLPRDLIQFIAG
RFTSNIRELEGAFTRAVAFASITGLPMTVQSIAPMLDPNSVGVVVTPKQVINKVSDFFKVSTDELISSSRRKPVSQARQI
GMYLMRHGTDLSLPRIGDEFGGKDHTTVMYAIEQVEKKLSIDPNIASQVQKIRDLLQIDSRKNL

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=444, Percent_Identity=38.5135135135135, Blast_Score=319, Evalue=3e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 52145; Mature: 52145

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQATNPIWAEVQQSLQKTLSKPSFETWIRPAKFNCFENGLLTLIAPNTFSSDWLRKNYCE
CCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHCCCCEEEEECCCCCHHHHHHHHHH
TIEKAAKEICGHDVKVVFKSETNTSSDLSNEDKANEKNVHHKTRSFSSNNQNNSSKNQFK
HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCC
NPNGLNLRYVFKRFVVGPNSRLAHAAALAVAESPGREFNPLFICGGVGLGKTHLMQAIGH
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHC
YRVEIDPEAKVKYVSTETFTNDVISGIRRDGMTAIRDKYRNVDLILIDDIQFLEGKEYTQ
EEEEECCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCHHHCCCCHHH
EEFFHTFNALHESGSQIVIASDRPPNQLSGIQERLISRFSMGMTADIQPPDLETRTAILQ
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
KKAEQERMSLPRDLIQFIAGRFTSNIRELEGAFTRAVAFASITGLPMTVQSIAPMLDPNS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCC
VGVVVTPKQVINKVSDFFKVSTDELISSSRRKPVSQARQIGMYLMRHGTDLSLPRIGDEF
CEEEECHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHH
GGKDHTTVMYAIEQVEKKLSIDPNIASQVQKIRDLLQIDSRKNL
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQATNPIWAEVQQSLQKTLSKPSFETWIRPAKFNCFENGLLTLIAPNTFSSDWLRKNYCE
CCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHCCCCEEEEECCCCCHHHHHHHHHH
TIEKAAKEICGHDVKVVFKSETNTSSDLSNEDKANEKNVHHKTRSFSSNNQNNSSKNQFK
HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCC
NPNGLNLRYVFKRFVVGPNSRLAHAAALAVAESPGREFNPLFICGGVGLGKTHLMQAIGH
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHC
YRVEIDPEAKVKYVSTETFTNDVISGIRRDGMTAIRDKYRNVDLILIDDIQFLEGKEYTQ
EEEEECCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCHHHCCCCHHH
EEFFHTFNALHESGSQIVIASDRPPNQLSGIQERLISRFSMGMTADIQPPDLETRTAILQ
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
KKAEQERMSLPRDLIQFIAGRFTSNIRELEGAFTRAVAFASITGLPMTVQSIAPMLDPNS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCC
VGVVVTPKQVINKVSDFFKVSTDELISSSRRKPVSQARQIGMYLMRHGTDLSLPRIGDEF
CEEEECHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHH
GGKDHTTVMYAIEQVEKKLSIDPNIASQVQKIRDLLQIDSRKNL
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA