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The map label for this gene is ppa [H]

Identifier: 123968103

GI number: 123968103

Start: 493975

End: 494529

Strand: Direct

Name: ppa [H]

Synonym: A9601_05681

Alternate gene names: 123968103

Gene position: 493975-494529 (Clockwise)

Preceding gene: 123968102

Following gene: 123968104

Centisome position: 29.58

GC content: 35.68

Gene sequence:

>555_bases
ATGGACCTTAGTTCAATACCTCCATCTCCAATGAAGGGAATAGTGAATATTGTTGTTGAAATACCTGCAGGGAGTAGGAA
TAAATATGAATACTGCTCTGATGCAGGAATAATGGCCCTAGACAGAGTATTACATTCTTCAGTGAGGTACCCTTTTGATT
ATGGTTTTATACCAAATACCCTTGCTGATGATGGAGCTCCCCTTGATGCAATGGTGATCATGGACGAACCTACTTTTGCG
GGTTGTCTAATAAAAGCTAGACCTATTGGAGTTTTGGATATGTATGATTGTGGTGCTTATGATGGAAAACTTTTATGTGT
GCCTATGGCTAATCCTAGGCAGGCTAATATAGTGAGTATTAATCAAATTGCGCCTAATCAGCTTGAGGATGTTGCAGAAT
TTTTTAGAACAAGTAAAGGACTCGATGGAAGAACAGTTCAAATTGATGGTTGGAGGGATTTTGATGTAGTTGAAAATTTA
TTGAAAAGTTGTTTGCCTTCAAAAAAGAAAAAATTTAAAGTACTTAAGAAATCAAATATTAGTAAATTAAATTGA

Upstream 100 bases:

>100_bases
TTTGCCTTTTTGACAATTTTTTTACCTTCAATAAGCATTTTAATTGGCAGACCTTTTTCTCAAGGAAACGAGATAATTCA
TAATCACGATTTTAAAAAAG

Downstream 100 bases:

>100_bases
AAAAAATAATTTTTTATAGTTATTTAAAATGCTCTACATGCCGAAAAGCTGCAAAGTGGCTTGAAAGCAAAGATTTTGAA
TTTCAGTTGATTGATATTGT

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MDLSSIPPSPMKGIVNIVVEIPAGSRNKYEYCSDAGIMALDRVLHSSVRYPFDYGFIPNTLADDGAPLDAMVIMDEPTFA
GCLIKARPIGVLDMYDCGAYDGKLLCVPMANPRQANIVSINQIAPNQLEDVAEFFRTSKGLDGRTVQIDGWRDFDVVENL
LKSCLPSKKKKFKVLKKSNISKLN

Sequences:

>Translated_184_residues
MDLSSIPPSPMKGIVNIVVEIPAGSRNKYEYCSDAGIMALDRVLHSSVRYPFDYGFIPNTLADDGAPLDAMVIMDEPTFA
GCLIKARPIGVLDMYDCGAYDGKLLCVPMANPRQANIVSINQIAPNQLEDVAEFFRTSKGLDGRTVQIDGWRDFDVVENL
LKSCLPSKKKKFKVLKKSNISKLN
>Mature_184_residues
MDLSSIPPSPMKGIVNIVVEIPAGSRNKYEYCSDAGIMALDRVLHSSVRYPFDYGFIPNTLADDGAPLDAMVIMDEPTFA
GCLIKARPIGVLDMYDCGAYDGKLLCVPMANPRQANIVSINQIAPNQLEDVAEFFRTSKGLDGRTVQIDGWRDFDVVENL
LKSCLPSKKKKFKVLKKSNISKLN

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=161, Percent_Identity=31.6770186335404, Blast_Score=91, Evalue=6e-20,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 20289; Mature: 20289

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSSIPPSPMKGIVNIVVEIPAGSRNKYEYCSDAGIMALDRVLHSSVRYPFDYGFIPNT
CCCCCCCCCHHHHEEEEEEECCCCCCCCCCHHCCCCHHHHHHHHHHHCCCCCCCCCCCCC
LADDGAPLDAMVIMDEPTFAGCLIKARPIGVLDMYDCGAYDGKLLCVPMANPRQANIVSI
CCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCEEEEEECCCCCCCCEEEE
NQIAPNQLEDVAEFFRTSKGLDGRTVQIDGWRDFDVVENLLKSCLPSKKKKFKVLKKSNI
CCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCC
SKLN
CCCC
>Mature Secondary Structure
MDLSSIPPSPMKGIVNIVVEIPAGSRNKYEYCSDAGIMALDRVLHSSVRYPFDYGFIPNT
CCCCCCCCCHHHHEEEEEEECCCCCCCCCCHHCCCCHHHHHHHHHHHCCCCCCCCCCCCC
LADDGAPLDAMVIMDEPTFAGCLIKARPIGVLDMYDCGAYDGKLLCVPMANPRQANIVSI
CCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCEEEEEECCCCCCCCEEEE
NQIAPNQLEDVAEFFRTSKGLDGRTVQIDGWRDFDVVENLLKSCLPSKKKKFKVLKKSNI
CCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCC
SKLN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]