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The map label for this gene is ribE [H]

Identifier: 123968034

GI number: 123968034

Start: 432932

End: 433585

Strand: Direct

Name: ribE [H]

Synonym: A9601_04971

Alternate gene names: 123968034

Gene position: 432932-433585 (Clockwise)

Preceding gene: 123968032

Following gene: 123968039

Centisome position: 25.93

GC content: 30.12

Gene sequence:

>654_bases
ATGTTTACAGGAATAATTCAGTCAGTAGGAAAACTAAGACAAGAAAAAAATATTGTAGAAATTGAAATTATAGATAATTT
ATTTGATATTGCAATCGGTGACAGCATAGCTGTTGATGGAATTTGTTTGACAGTTAAAGAGATTTTTCAAAATAAATTTA
CTGTTGATGTTAGTGAGGAGACATTAAAAAAAACAACTTTAGGAGTAAAGTTGAACCTGAATCAGATTGTTAATTTGGAG
CCCGCTCTTAGGGTGTCTGACCGTCTAGGAGGGCATATAGTTAGCGGACATGTTGATGGCCTTGGAACAGTTGAAAATAT
AGAAAAATTAGAGAAATCTTGGCTCTTATCAATAAAGTGGAAAAATAAAAATTTTTCAAAATATGTAGTTAATAAAGGAA
GTATTTGTGTAAATGGTATTAGTCTTACGATTGCAAAATATGAGCAGGAAGGAGAAATATTTACTATTGCGATAATTCCT
CATACTTGGCATAACACAAATCTGAATAAATTAAATATCGGTGACAGTGTTAACCTTGAGGCAGATGCACTAATTAAATA
TGTAGAGAAATTACTTTTATTTAATAAAAATAGTAATCAAGATTTATCTTCAAAAAATATTTCTTCCGAGTGGCTTAAAG
AAAACGGTTGGTAA

Upstream 100 bases:

>100_bases
ATTTCTTTTTTATTTACTCTTTAATTTATTTATAGTTGAAAATCATTTAAAGTAAATTAAAGTAAATACAAAATTTTGCA
AAAATATTTTTCTTAAATCT

Downstream 100 bases:

>100_bases
AATATATCTTTTAATTTAGTGGAATCAGATAAATTGTTTTTGATTCTTTTTTAAGATCGATTTTAAATTCCTGACCAGGT
TGTAGACCTAATTTTTTGGT

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MFTGIIQSVGKLRQEKNIVEIEIIDNLFDIAIGDSIAVDGICLTVKEIFQNKFTVDVSEETLKKTTLGVKLNLNQIVNLE
PALRVSDRLGGHIVSGHVDGLGTVENIEKLEKSWLLSIKWKNKNFSKYVVNKGSICVNGISLTIAKYEQEGEIFTIAIIP
HTWHNTNLNKLNIGDSVNLEADALIKYVEKLLLFNKNSNQDLSSKNISSEWLKENGW

Sequences:

>Translated_217_residues
MFTGIIQSVGKLRQEKNIVEIEIIDNLFDIAIGDSIAVDGICLTVKEIFQNKFTVDVSEETLKKTTLGVKLNLNQIVNLE
PALRVSDRLGGHIVSGHVDGLGTVENIEKLEKSWLLSIKWKNKNFSKYVVNKGSICVNGISLTIAKYEQEGEIFTIAIIP
HTWHNTNLNKLNIGDSVNLEADALIKYVEKLLLFNKNSNQDLSSKNISSEWLKENGW
>Mature_217_residues
MFTGIIQSVGKLRQEKNIVEIEIIDNLFDIAIGDSIAVDGICLTVKEIFQNKFTVDVSEETLKKTTLGVKLNLNQIVNLE
PALRVSDRLGGHIVSGHVDGLGTVENIEKLEKSWLLSIKWKNKNFSKYVVNKGSICVNGISLTIAKYEQEGEIFTIAIIP
HTWHNTNLNKLNIGDSVNLEADALIKYVEKLLLFNKNSNQDLSSKNISSEWLKENGW

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=208, Percent_Identity=36.0576923076923, Blast_Score=110, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6319733, Length=231, Percent_Identity=35.0649350649351, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 24309; Mature: 24309

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIIQSVGKLRQEKNIVEIEIIDNLFDIAIGDSIAVDGICLTVKEIFQNKFTVDVSEE
CCHHHHHHHHHHHHHCCEEEEEEECCHHHHHCCCCEEECHHHEEHHHHHCCCEEEEECHH
TLKKTTLGVKLNLNQIVNLEPALRVSDRLGGHIVSGHVDGLGTVENIEKLEKSWLLSIKW
HHHHHHEEEEEEHHHEECCCCCEEEHHHCCCEEEECCCCCCCCHHHHHHHHHHEEEEEEE
KNKNFSKYVVNKGSICVNGISLTIAKYEQEGEIFTIAIIPHTWHNTNLNKLNIGDSVNLE
CCCCCEEEEECCCCEEEECEEEEEEEECCCCCEEEEEEEECCCCCCCCCEEECCCCCCCC
ADALIKYVEKLLLFNKNSNQDLSSKNISSEWLKENGW
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MFTGIIQSVGKLRQEKNIVEIEIIDNLFDIAIGDSIAVDGICLTVKEIFQNKFTVDVSEE
CCHHHHHHHHHHHHHCCEEEEEEECCHHHHHCCCCEEECHHHEEHHHHHCCCEEEEECHH
TLKKTTLGVKLNLNQIVNLEPALRVSDRLGGHIVSGHVDGLGTVENIEKLEKSWLLSIKW
HHHHHHEEEEEEHHHEECCCCCEEEHHHCCCEEEECCCCCCCCHHHHHHHHHHEEEEEEE
KNKNFSKYVVNKGSICVNGISLTIAKYEQEGEIFTIAIIPHTWHNTNLNKLNIGDSVNLE
CCCCCEEEEECCCCEEEECEEEEEEEECCCCCEEEEEEEECCCCCCCCCEEECCCCCCCC
ADALIKYVEKLLLFNKNSNQDLSSKNISSEWLKENGW
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]