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The map label for this gene is pip [H]

Identifier: 123967928

GI number: 123967928

Start: 348325

End: 349275

Strand: Direct

Name: pip [H]

Synonym: A9601_03911

Alternate gene names: 123967928

Gene position: 348325-349275 (Clockwise)

Preceding gene: 123967927

Following gene: 123967931

Centisome position: 20.86

GC content: 30.49

Gene sequence:

>951_bases
ATGAAAGATCAAGTCTTGTTCCCGAAAATTGAAGTACGTGAAAAGGGTTTTTTACAAGTTAGTGATATTCATACTATTTA
TTGGGAAAGATCTGGCAATCCAAATGGCAAAAAAATACTTGTTATTCATGGAGGCCCAGGAGGAGGAAGTCAACCAAGAT
ATAGAAGATACTTTGACCCAGATAAATTCGATATTATTCAATTTGACCAAAGAGGTTGCGGTTCTTCAACTCCTTTCTCC
GAATTAAAAGAAAATACGACTAATCATTTAGTAGATGATATTGAGAAATTAAGGATTCTTTTTAAAATAGATACTTGGCA
TTTGTTTGGTGGATCTTGGGGCTCAACACTTTCACTAATATATGCAATTAAAAATCCCTCAAGAGTTATAAGCTTAACTT
TGCGAGGAATATTTTTATGTAGAAAGTTTGAATTATTATGGTTCTATCAATATGGTGCAAGTGAGATATTCCCTGATGTA
TTTGAAGAATATATTTCTGTAATACCAAAAGAAGAAAGAAATGATTTGATAAGTTCTTTTTACAAATATCTAACATCTAC
AGATTCGAATCTTAGATCAAAAGCTGCAGCAGCTTGGACAAAATGGGAACTCTCAACTAGTCATTTAATAAATAAAAAAT
TCGATTTTGATAAGTCCCAAGTTAATTCTTTTTCAGATGCCTTTGCGAGGATAGAATGTCATTATTTTATTAATAATATT
TTCTTAGAAGATGATTTTATTTTGAAAAATTTGAAAACAATAGAATCGATTCCAACAAAAATAATTCAAGGTAGGTATGA
CGTTGTATGTCCTGTTAGGAGTGCATGGGATCTAAATAAGAAATTAAAGAATTCTGAATTAATTATTGTTAATGATGCAG
GTCATTCAATGAGTGAGGAAGGCATTAGTATCGAATTAATAAAAGCTGTAAAAGGAATTCAAAATCTCTAA

Upstream 100 bases:

>100_bases
GGACTGTTTATACAGTCCTTTTTTTGTTTGACAAATTACTTCTAAACTAGACTTCTTTTTGGATAATATAGATAAATAAA
GTGATTAAAAATATTTCAAA

Downstream 100 bases:

>100_bases
AAGAGGGAATATTTCTTCAAAAATTAAAGGCCATTATCTTCAATATTTTGTGCAATACTCCTCAGAAGTTCGACGATATC
AGAATCTTCGCATTGAGTAT

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKDQVLFPKIEVREKGFLQVSDIHTIYWERSGNPNGKKILVIHGGPGGGSQPRYRRYFDPDKFDIIQFDQRGCGSSTPFS
ELKENTTNHLVDDIEKLRILFKIDTWHLFGGSWGSTLSLIYAIKNPSRVISLTLRGIFLCRKFELLWFYQYGASEIFPDV
FEEYISVIPKEERNDLISSFYKYLTSTDSNLRSKAAAAWTKWELSTSHLINKKFDFDKSQVNSFSDAFARIECHYFINNI
FLEDDFILKNLKTIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIVNDAGHSMSEEGISIELIKAVKGIQNL

Sequences:

>Translated_316_residues
MKDQVLFPKIEVREKGFLQVSDIHTIYWERSGNPNGKKILVIHGGPGGGSQPRYRRYFDPDKFDIIQFDQRGCGSSTPFS
ELKENTTNHLVDDIEKLRILFKIDTWHLFGGSWGSTLSLIYAIKNPSRVISLTLRGIFLCRKFELLWFYQYGASEIFPDV
FEEYISVIPKEERNDLISSFYKYLTSTDSNLRSKAAAAWTKWELSTSHLINKKFDFDKSQVNSFSDAFARIECHYFINNI
FLEDDFILKNLKTIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIVNDAGHSMSEEGISIELIKAVKGIQNL
>Mature_316_residues
MKDQVLFPKIEVREKGFLQVSDIHTIYWERSGNPNGKKILVIHGGPGGGSQPRYRRYFDPDKFDIIQFDQRGCGSSTPFS
ELKENTTNHLVDDIEKLRILFKIDTWHLFGGSWGSTLSLIYAIKNPSRVISLTLRGIFLCRKFELLWFYQYGASEIFPDV
FEEYISVIPKEERNDLISSFYKYLTSTDSNLRSKAAAAWTKWELSTSHLINKKFDFDKSQVNSFSDAFARIECHYFINNI
FLEDDFILKNLKTIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIVNDAGHSMSEEGISIELIKAVKGIQNL

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 36445; Mature: 36445

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDQVLFPKIEVREKGFLQVSDIHTIYWERSGNPNGKKILVIHGGPGGGSQPRYRRYFDP
CCCCEECCEEEECCCCCEEEECEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
DKFDIIQFDQRGCGSSTPFSELKENTTNHLVDDIEKLRILFKIDTWHLFGGSWGSTLSLI
CCEEEEEECCCCCCCCCCHHHHHHCHHHHHHHHHHHEEEEEEEEEEEEECCCCCCEEEEE
YAIKNPSRVISLTLRGIFLCRKFELLWFYQYGASEIFPDVFEEYISVIPKEERNDLISSF
EEECCCCCEEHHHHHHHHHHHHEEEEEEEECCCHHCCHHHHHHHHHHCCCCHHHHHHHHH
YKYLTSTDSNLRSKAAAAWTKWELSTSHLINKKFDFDKSQVNSFSDAFARIECHYFINNI
HHHHHCCCCHHHHHHHHHEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHEEEEEEEEEE
FLEDDFILKNLKTIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIVNDAGHSMSEE
EECCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHCHHHHCCCCCEEEEECCCCCCCCC
GISIELIKAVKGIQNL
CCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKDQVLFPKIEVREKGFLQVSDIHTIYWERSGNPNGKKILVIHGGPGGGSQPRYRRYFDP
CCCCEECCEEEECCCCCEEEECEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
DKFDIIQFDQRGCGSSTPFSELKENTTNHLVDDIEKLRILFKIDTWHLFGGSWGSTLSLI
CCEEEEEECCCCCCCCCCHHHHHHCHHHHHHHHHHHEEEEEEEEEEEEECCCCCCEEEEE
YAIKNPSRVISLTLRGIFLCRKFELLWFYQYGASEIFPDVFEEYISVIPKEERNDLISSF
EEECCCCCEEHHHHHHHHHHHHEEEEEEEECCCHHCCHHHHHHHHHHCCCCHHHHHHHHH
YKYLTSTDSNLRSKAAAAWTKWELSTSHLINKKFDFDKSQVNSFSDAFARIECHYFINNI
HHHHHCCCCHHHHHHHHHEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHEEEEEEEEEE
FLEDDFILKNLKTIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIVNDAGHSMSEE
EECCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHCHHHHCCCCCEEEEECCCCCCCCC
GISIELIKAVKGIQNL
CCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA