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The map label for this gene is fabD [H]

Identifier: 123967691

GI number: 123967691

Start: 145151

End: 146047

Strand: Direct

Name: fabD [H]

Synonym: A9601_01541

Alternate gene names: 123967691

Gene position: 145151-146047 (Clockwise)

Preceding gene: 161353819

Following gene: 123967692

Centisome position: 8.69

GC content: 31.22

Gene sequence:

>897_bases
ATGAAAGTTGCATGGGTATTCCCTGGACAGGGTTCGCAAAAAATTGGAATGGCAAAACAAATTGAAAATCTGCCGATCAC
AAAAGAGAGGTTTAGCTATGCTTCTGAGATATTTGAGAGAAATTTATTTGAAATTTGTGAATTAAATACTGAACCAACAA
ATCCTCTTCTTGATTTGAATTACACAAAAAATACACAAATTTGTCTTTTTTTAGTTGAATCAATTTTATTAGATGCATTA
AAGGAAAATGGATTTAAACCAACTTATGTTGCGGGACACAGTCTTGGAGAAATCACTGCACTATATTGTTCGGATGTTTT
TTCATTCGAAGATTGTGTTTCTCTTATAAAAGAAAGGTCTCAATTAATGGTCAATGCTGGTAAAGGATCTATGGCAGCAG
TAATTGGTTTTGATAGAAATCAACTTGATTTATTAGTGCAAAAAATTGATGATATTGTAATTGCTAATGATAATAGCTCT
TCCCAAGTTGTCTTATCAGGATCTACTGAAGCCTTAGATAATTTATCGAAAGAAATTGCTTGTAAAAGATTCTTGAAATT
AAATGTTTCAGGAGCATTTCATTCACCATTTATGAATGAACCTTCATCAAAATTTTGTGAGTATTTAAAAAAGATTAAAT
TTAACAATCCTTCTTTCCCTGTGATAAGTAATTATGAACCTTCACTGTGTAGCGATCCAAACGAGCTTAAAATTAGATTA
GAAAAGCAAATGTGTAATGGAGTGAGGTGGCGAGAAACTATGGATTTAATGGCAAAAGATAGTGATCTTCATATTGTCGA
AATTGGCCCTTCTAATGTACTAAGTGGTTTAGCAAAAAGACATCTTAAAGATGTAAAAATTTCTCAAGTATCATCTTCTG
ATCAAATATCTTATTAA

Upstream 100 bases:

>100_bases
TATAGAATTAAACAAAATGATATTATTGCTACAAGTGGTTTCGGTGCTGGGCTAAGTTGGGGTGCAGCCCTAATTAAATG
GGGTTAAAAAAAGGAGCATT

Downstream 100 bases:

>100_bases
TTTGTATGAAAAATCATACTATTCAAAAATTAATCTATGAATTAGTTAGCAAGCTTTTTGTATTTCCTATTTATAAATTT
GTTTTTAAAGGTCATTTAAT

Product: malonyl coenzyme A-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MKVAWVFPGQGSQKIGMAKQIENLPITKERFSYASEIFERNLFEICELNTEPTNPLLDLNYTKNTQICLFLVESILLDAL
KENGFKPTYVAGHSLGEITALYCSDVFSFEDCVSLIKERSQLMVNAGKGSMAAVIGFDRNQLDLLVQKIDDIVIANDNSS
SQVVLSGSTEALDNLSKEIACKRFLKLNVSGAFHSPFMNEPSSKFCEYLKKIKFNNPSFPVISNYEPSLCSDPNELKIRL
EKQMCNGVRWRETMDLMAKDSDLHIVEIGPSNVLSGLAKRHLKDVKISQVSSSDQISY

Sequences:

>Translated_298_residues
MKVAWVFPGQGSQKIGMAKQIENLPITKERFSYASEIFERNLFEICELNTEPTNPLLDLNYTKNTQICLFLVESILLDAL
KENGFKPTYVAGHSLGEITALYCSDVFSFEDCVSLIKERSQLMVNAGKGSMAAVIGFDRNQLDLLVQKIDDIVIANDNSS
SQVVLSGSTEALDNLSKEIACKRFLKLNVSGAFHSPFMNEPSSKFCEYLKKIKFNNPSFPVISNYEPSLCSDPNELKIRL
EKQMCNGVRWRETMDLMAKDSDLHIVEIGPSNVLSGLAKRHLKDVKISQVSSSDQISY
>Mature_298_residues
MKVAWVFPGQGSQKIGMAKQIENLPITKERFSYASEIFERNLFEICELNTEPTNPLLDLNYTKNTQICLFLVESILLDAL
KENGFKPTYVAGHSLGEITALYCSDVFSFEDCVSLIKERSQLMVNAGKGSMAAVIGFDRNQLDLLVQKIDDIVIANDNSS
SQVVLSGSTEALDNLSKEIACKRFLKLNVSGAFHSPFMNEPSSKFCEYLKKIKFNNPSFPVISNYEPSLCSDPNELKIRL
EKQMCNGVRWRETMDLMAKDSDLHIVEIGPSNVLSGLAKRHLKDVKISQVSSSDQISY

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=24.5847176079734, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1787334, Length=288, Percent_Identity=34.0277777777778, Blast_Score=157, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI71984332, Length=273, Percent_Identity=24.1758241758242, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17550940, Length=301, Percent_Identity=27.906976744186, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24665753, Length=273, Percent_Identity=30.7692307692308, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33370; Mature: 33370

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAWVFPGQGSQKIGMAKQIENLPITKERFSYASEIFERNLFEICELNTEPTNPLLDLN
CEEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC
YTKNTQICLFLVESILLDALKENGFKPTYVAGHSLGEITALYCSDVFSFEDCVSLIKERS
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
QLMVNAGKGSMAAVIGFDRNQLDLLVQKIDDIVIANDNSSSQVVLSGSTEALDNLSKEIA
HEEEECCCCCEEEEEECCCHHHHHHHHHHCCEEEECCCCCCEEEEECCHHHHHHHHHHHH
CKRFLKLNVSGAFHSPFMNEPSSKFCEYLKKIKFNNPSFPVISNYEPSLCSDPNELKIRL
HHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHEEE
EKQMCNGVRWRETMDLMAKDSDLHIVEIGPSNVLSGLAKRHLKDVKISQVSSSDQISY
EHHHHCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKVAWVFPGQGSQKIGMAKQIENLPITKERFSYASEIFERNLFEICELNTEPTNPLLDLN
CEEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC
YTKNTQICLFLVESILLDALKENGFKPTYVAGHSLGEITALYCSDVFSFEDCVSLIKERS
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
QLMVNAGKGSMAAVIGFDRNQLDLLVQKIDDIVIANDNSSSQVVLSGSTEALDNLSKEIA
HEEEECCCCCEEEEEECCCHHHHHHHHHHCCEEEECCCCCCEEEEECCHHHHHHHHHHHH
CKRFLKLNVSGAFHSPFMNEPSSKFCEYLKKIKFNNPSFPVISNYEPSLCSDPNELKIRL
HHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHEEE
EKQMCNGVRWRETMDLMAKDSDLHIVEIGPSNVLSGLAKRHLKDVKISQVSSSDQISY
EHHHHCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]