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The map label for this gene is cysH [H]

Identifier: 123967631

GI number: 123967631

Start: 97149

End: 97871

Strand: Reverse

Name: cysH [H]

Synonym: A9601_00941

Alternate gene names: 123967631

Gene position: 97871-97149 (Counterclockwise)

Preceding gene: 123967636

Following gene: 123967630

Centisome position: 5.86

GC content: 31.67

Gene sequence:

>723_bases
ATGATTGAAAAAATTCACAAAGATATTCAAACTAACTTGAGGAAATATAATCAAGATCTTGTAGATATGAAGCCTCAAGC
AATGCTTACATGGGGTTATAAAAAATTTGATAAACAATTTGCTATTACAACAAGTTTTGGTATACAGTCATCAGTCCTTT
TAGATATGGTCAGCAAATTATCCCTACAAAAAAAAATCAAAATATTTTGGATAGATACAGGTTACCTTCCTCCAGAAACA
TACCATTACGCTGAAAAGCTTATTGATAATTTATCCTTAGAAGTTGAAGTTCTGCAAAGTGAATTATCTCCAGCAAGAAT
GGAAGCCAAATATGGAAAACTTTGGGAAACAAAAAAAGAGAGTGATTTAGATAAGTATCATGAATTGAGAAAGATAAAAC
CTTTAGAAAATGGTCTAGAAAAATATGATATTTCCTGCTGGGCAAACGGCGTTAGATCAAGTCAAACAGAAAATAGAAAC
AAAATGAAATTCATAGACGTAATTCGTCAAAGGCTCTCTTTAAGACCTTTATTAAATTGGACAAATAAAGATATTTTTTA
TTATATGGAAGAGAATAATTTGCCTGCCCATCCACTTTTTATCAAAGGTTATTCTTCTGTAGGAGATTGGCATTCAAGCA
GTCCCGATGGTCTTGAAACAAAGGGCAGAGATACAAGATTTGGAGGAATTAAACAAGAATGTGGGATTCACACTAATAAT
TAA

Upstream 100 bases:

>100_bases
TTCATTAGAGAAATATTGATATGCGTAAATGTATTATTAAACTATACGAATAATTTATAAATTGAGCGAAATAAAATTAA
ACTCATAATCAAACTGAAGA

Downstream 100 bases:

>100_bases
ATTGATCATAGAAAAATGGTCTCAGAAATAAATTTTTTATTAGTAGGCAATAGTAGGCTTCATTGGGCTCAATATTCTAA
AAATCAATCTAAATTCTTCC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MIEKIHKDIQTNLRKYNQDLVDMKPQAMLTWGYKKFDKQFAITTSFGIQSSVLLDMVSKLSLQKKIKIFWIDTGYLPPET
YHYAEKLIDNLSLEVEVLQSELSPARMEAKYGKLWETKKESDLDKYHELRKIKPLENGLEKYDISCWANGVRSSQTENRN
KMKFIDVIRQRLSLRPLLNWTNKDIFYYMEENNLPAHPLFIKGYSSVGDWHSSSPDGLETKGRDTRFGGIKQECGIHTNN

Sequences:

>Translated_240_residues
MIEKIHKDIQTNLRKYNQDLVDMKPQAMLTWGYKKFDKQFAITTSFGIQSSVLLDMVSKLSLQKKIKIFWIDTGYLPPET
YHYAEKLIDNLSLEVEVLQSELSPARMEAKYGKLWETKKESDLDKYHELRKIKPLENGLEKYDISCWANGVRSSQTENRN
KMKFIDVIRQRLSLRPLLNWTNKDIFYYMEENNLPAHPLFIKGYSSVGDWHSSSPDGLETKGRDTRFGGIKQECGIHTNN
>Mature_240_residues
MIEKIHKDIQTNLRKYNQDLVDMKPQAMLTWGYKKFDKQFAITTSFGIQSSVLLDMVSKLSLQKKIKIFWIDTGYLPPET
YHYAEKLIDNLSLEVEVLQSELSPARMEAKYGKLWETKKESDLDKYHELRKIKPLENGLEKYDISCWANGVRSSQTENRN
KMKFIDVIRQRLSLRPLLNWTNKDIFYYMEENNLPAHPLFIKGYSSVGDWHSSSPDGLETKGRDTRFGGIKQECGIHTNN

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=225, Percent_Identity=32.8888888888889, Blast_Score=152, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6325425, Length=243, Percent_Identity=32.5102880658436, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 28075; Mature: 28075

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEKIHKDIQTNLRKYNQDLVDMKPQAMLTWGYKKFDKQFAITTSFGIQSSVLLDMVSKL
CHHHHHHHHHHHHHHHCHHHHCCCCCCEEEHHHHHHCCEEEEEECCCCHHHHHHHHHHHH
SLQKKIKIFWIDTGYLPPETYHYAEKLIDNLSLEVEVLQSELSPARMEAKYGKLWETKKE
HHHCEEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCC
SDLDKYHELRKIKPLENGLEKYDISCWANGVRSSQTENRNKMKFIDVIRQRLSLRPLLNW
CHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
TNKDIFYYMEENNLPAHPLFIKGYSSVGDWHSSSPDGLETKGRDTRFGGIKQECGIHTNN
CCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MIEKIHKDIQTNLRKYNQDLVDMKPQAMLTWGYKKFDKQFAITTSFGIQSSVLLDMVSKL
CHHHHHHHHHHHHHHHCHHHHCCCCCCEEEHHHHHHCCEEEEEECCCCHHHHHHHHHHHH
SLQKKIKIFWIDTGYLPPETYHYAEKLIDNLSLEVEVLQSELSPARMEAKYGKLWETKKE
HHHCEEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCC
SDLDKYHELRKIKPLENGLEKYDISCWANGVRSSQTENRNKMKFIDVIRQRLSLRPLLNW
CHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
TNKDIFYYMEENNLPAHPLFIKGYSSVGDWHSSSPDGLETKGRDTRFGGIKQECGIHTNN
CCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1463852 [H]