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The map label for this gene is thiL [H]

Identifier: 123967560

GI number: 123967560

Start: 25105

End: 26091

Strand: Reverse

Name: thiL [H]

Synonym: A9601_00231

Alternate gene names: 123967560

Gene position: 26091-25105 (Counterclockwise)

Preceding gene: 123967561

Following gene: 123967558

Centisome position: 1.56

GC content: 29.79

Gene sequence:

>987_bases
ATGCATAAAGAAATACTAGAAGATATTGGGGAAAAAGAATTAATTAATAGGCTAGGAAAATTTATGCCTAAAAATCAAGT
TTCAGATGATTGCGCTTTGATTAAAACTAAAAATGAAAATTTACTTGTTAATACTGATTCTTTGGTAGAAAATGTTCATT
TTAATACAATTTCTATTTGTCCTCAAGACCTTGGTTGGAAAGCTGTTGTTAGCAACATCTCTGACTTATTATCAAGTGGA
AGCAAAAAAACTATAGGTATTACAATAAGCCTAATTTTACCTGCTAAAACTGAGTGGATTTGGATTGAAGAATTATACAA
AGGGATAAATAAAGCATTAAAAAAATATGGCGGGCTTATTCTAGGGGGAGATTGTTCAAAAGGGAATGAAAAAATCATTT
CAATTACAGCCTTTGGGATTCAAGGTGAACTTGAATTACGAAGAAACGCATGTAAAGCAGGAGATATTATCTTAACGACA
GGAATGCATGGCCTTAGCAAGCTAGGCTTTATGATACAAAATAAAATAAATTTCGATAATAATTTTTCTCTAAATGAAAG
ATTAATCAGTAAGTCAATTAAACATTTTTGTCGCCCGAAAGTTTACCCAATTTTTCTCACAAATCTCATTAAAACTCGAT
CCAATAAAAAAATAAGAAGAATAGGGTGTACTGATAGTAGCGACGGTCTTTTTCAATCTATACAAGATTTAGCAATAGCT
AGCAACTGTAAAGCGATCATGAATTATGAAAAAATGCCCAAAGATAAGAATTGGCCAAAAGGAGATAAATGGGATGAATA
TTATTTTTTTGGAGGTGAAGATTACGAATTAGTATTCTCTTTACCCAAAAAATGGGCCAATAATTTATGCAAACTCGATA
AAAATATTTACGAGATTGGTTATTTCGTTAATGGTAAACCATCAATAGAATTTAAAGATAAAAATAAAAATCATTTATTG
AAAAATATACCTTTCAAGCACTTTTAA

Upstream 100 bases:

>100_bases
GGTTACGTTGTAGATGGATTTGATGTATTAGAAGAACTGACTAAAGATGACACAATAATTTCAATTGATGTTTTAGAAGG
GATTCAAAACCTCAAATTAA

Downstream 100 bases:

>100_bases
TTATTCCCAATTTTTAGCAACAATCTCTGCTAAATCAACAACCCTTTGACTATAGCCCCACTCGTTGTCATACCAAGCAA
GGACCTTAACAAGATTGTCG

Product: putative thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MHKEILEDIGEKELINRLGKFMPKNQVSDDCALIKTKNENLLVNTDSLVENVHFNTISICPQDLGWKAVVSNISDLLSSG
SKKTIGITISLILPAKTEWIWIEELYKGINKALKKYGGLILGGDCSKGNEKIISITAFGIQGELELRRNACKAGDIILTT
GMHGLSKLGFMIQNKINFDNNFSLNERLISKSIKHFCRPKVYPIFLTNLIKTRSNKKIRRIGCTDSSDGLFQSIQDLAIA
SNCKAIMNYEKMPKDKNWPKGDKWDEYYFFGGEDYELVFSLPKKWANNLCKLDKNIYEIGYFVNGKPSIEFKDKNKNHLL
KNIPFKHF

Sequences:

>Translated_328_residues
MHKEILEDIGEKELINRLGKFMPKNQVSDDCALIKTKNENLLVNTDSLVENVHFNTISICPQDLGWKAVVSNISDLLSSG
SKKTIGITISLILPAKTEWIWIEELYKGINKALKKYGGLILGGDCSKGNEKIISITAFGIQGELELRRNACKAGDIILTT
GMHGLSKLGFMIQNKINFDNNFSLNERLISKSIKHFCRPKVYPIFLTNLIKTRSNKKIRRIGCTDSSDGLFQSIQDLAIA
SNCKAIMNYEKMPKDKNWPKGDKWDEYYFFGGEDYELVFSLPKKWANNLCKLDKNIYEIGYFVNGKPSIEFKDKNKNHLL
KNIPFKHF
>Mature_328_residues
MHKEILEDIGEKELINRLGKFMPKNQVSDDCALIKTKNENLLVNTDSLVENVHFNTISICPQDLGWKAVVSNISDLLSSG
SKKTIGITISLILPAKTEWIWIEELYKGINKALKKYGGLILGGDCSKGNEKIISITAFGIQGELELRRNACKAGDIILTT
GMHGLSKLGFMIQNKINFDNNFSLNERLISKSIKHFCRPKVYPIFLTNLIKTRSNKKIRRIGCTDSSDGLFQSIQDLAIA
SNCKAIMNYEKMPKDKNWPKGDKWDEYYFFGGEDYELVFSLPKKWANNLCKLDKNIYEIGYFVNGKPSIEFKDKNKNHLL
KNIPFKHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=266, Percent_Identity=30.4511278195489, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 37339; Mature: 37339

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKEILEDIGEKELINRLGKFMPKNQVSDDCALIKTKNENLLVNTDSLVENVHFNTISIC
CCHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEECHHHHHHCCCCEEEEC
PQDLGWKAVVSNISDLLSSGSKKTIGITISLILPAKTEWIWIEELYKGINKALKKYGGLI
CCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCEE
LGGDCSKGNEKIISITAFGIQGELELRRNACKAGDIILTTGMHGLSKLGFMIQNKINFDN
EECCCCCCCCEEEEEEEECCCCHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCC
NFSLNERLISKSIKHFCRPKVYPIFLTNLIKTRSNKKIRRIGCTDSSDGLFQSIQDLAIA
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHH
SNCKAIMNYEKMPKDKNWPKGDKWDEYYFFGGEDYELVFSLPKKWANNLCKLDKNIYEIG
HCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHCCCCEEEE
YFVNGKPSIEFKDKNKNHLLKNIPFKHF
EEECCCCCEEECCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MHKEILEDIGEKELINRLGKFMPKNQVSDDCALIKTKNENLLVNTDSLVENVHFNTISIC
CCHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEECHHHHHHCCCCEEEEC
PQDLGWKAVVSNISDLLSSGSKKTIGITISLILPAKTEWIWIEELYKGINKALKKYGGLI
CCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCEE
LGGDCSKGNEKIISITAFGIQGELELRRNACKAGDIILTTGMHGLSKLGFMIQNKINFDN
EECCCCCCCCEEEEEEEECCCCHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCC
NFSLNERLISKSIKHFCRPKVYPIFLTNLIKTRSNKKIRRIGCTDSSDGLFQSIQDLAIA
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHH
SNCKAIMNYEKMPKDKNWPKGDKWDEYYFFGGEDYELVFSLPKKWANNLCKLDKNIYEIG
HCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHCCCCEEEE
YFVNGKPSIEFKDKNKNHLLKNIPFKHF
EEECCCCCEEECCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA