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The map label for this gene is lig2 [H]

Identifier: 123967103

GI number: 123967103

Start: 1658221

End: 1659459

Strand: Direct

Name: lig2 [H]

Synonym: P9515_18701

Alternate gene names: 123967103

Gene position: 1658221-1659459 (Clockwise)

Preceding gene: 123967102

Following gene: 123967104

Centisome position: 97.3

GC content: 35.84

Gene sequence:

>1239_bases
ATGAAAAAAGGGCTTAATGATTTTTTTGATGGAATACGTATGGCCTTAGATCCCTTAGTAACTTTTGGTGTAAAGCAAGT
GCCAGAGAAAGTAGAAGAGACATCTAATAAAGGATGTAAATGGAGTGATTTTAAAGGATTAACAACTCAATTGATCCAAA
GAGAACTGACTGGGTATGCCGCTAGAGATGCGATCAAATCAGTTATGAACTCTGCGACTAAAGAGCAATGGAACGGATTT
TACAGACGAGTATTAATTAAAGACCTCCGCTGTGGTGTTTCTGAAAAAACAATTAACAAAGTTGCAAAAAAATTTCCACA
GTATGCGATACCTATATTCTCGTGTCCCCTTGCTCATGACAGCGCAAACCATGAAAAGAAAATGATAGGCAAAAAACAAA
TTGAAATTAAACTAGACGGAGTCAGAGTATTGACAATTATTAGGAATAATAAAGTAGAAATGTTTTCGCGCAACGGCAAG
CAGTTTCATAACTTTGGTCATATCATTGCAGAAATAGAAAAAGTATTAGAAAAACATCCTGATCCCCAAGATTTAGTATT
AGACGGTGAAGTGATGAGTGCTAATTTCCAAGACCTGATGAAGCAAGTTCACAGAAAAGATGGTAAAGAATCAAAAGATG
CAGTCTTACACTTATTTGATATATGTCCACTTAAAAATTTCAAGGAGGGTTTATGGAAAAAACCCCAAACCACAAGAAGT
ATGCTGGTAAAAGATTGGGTAACAAAAAATTCAACTTTTTTAAAACATGTCCAAACACTCGATTGGGAAGATGTGGATTT
AGATACTACTAAGGGACAAATGAGATTTATAGAACTTAATAAAGAAGCAGTAGAGGGAGGGTATGAAGGCGTTATGATTA
AAAATCCTAATGCTTGGTATGAATGCAAAAGAACACATAGTTGGTTAAAAGCAAAACCATTCATAGAAGTTACATTGAGA
GTTGTAGCAATAGAAGAAGGAACAGGCCGAAACGAAGGTAGGCTTGGAGCCATCCTGGTTGAAGGTGAAGATGATAAATA
TAATTATCGACTTAATTGCGGGAGTGGATTTAGTGACTCTCAACGTGAAGAATATTGGAGTGAAAGAGATCAAATAATCG
GCCAATTGGTAGAAATCAGAGCTGATGCAAGAACTAAATCTCAAGATGCTGAAACCTTTAGTCTTAGATTCCCAAGATTC
AAATGCTTTAGAGGATTCGAACCAGGTCAAAAAATCTAA

Upstream 100 bases:

>100_bases
AATACTTGTGAAACATCAAGAACTTCGGGAAGAAGAAATAATAAAAAAATTAGAATTAAACCCAAGCAGGTTAGATAAAG
AACAAATCATTTTTGAAGCA

Downstream 100 bases:

>100_bases
TTTTCAATGGGATTACTTTTGTGATAGTGAGTATTTAAACTGGTGGTAAATCATGCAATAAAGTATCTATTATTAATAAA
TTACAATTGAAAATTATTCG

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] 2 [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKKGLNDFFDGIRMALDPLVTFGVKQVPEKVEETSNKGCKWSDFKGLTTQLIQRELTGYAARDAIKSVMNSATKEQWNGF
YRRVLIKDLRCGVSEKTINKVAKKFPQYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRNNKVEMFSRNGK
QFHNFGHIIAEIEKVLEKHPDPQDLVLDGEVMSANFQDLMKQVHRKDGKESKDAVLHLFDICPLKNFKEGLWKKPQTTRS
MLVKDWVTKNSTFLKHVQTLDWEDVDLDTTKGQMRFIELNKEAVEGGYEGVMIKNPNAWYECKRTHSWLKAKPFIEVTLR
VVAIEEGTGRNEGRLGAILVEGEDDKYNYRLNCGSGFSDSQREEYWSERDQIIGQLVEIRADARTKSQDAETFSLRFPRF
KCFRGFEPGQKI

Sequences:

>Translated_412_residues
MKKGLNDFFDGIRMALDPLVTFGVKQVPEKVEETSNKGCKWSDFKGLTTQLIQRELTGYAARDAIKSVMNSATKEQWNGF
YRRVLIKDLRCGVSEKTINKVAKKFPQYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRNNKVEMFSRNGK
QFHNFGHIIAEIEKVLEKHPDPQDLVLDGEVMSANFQDLMKQVHRKDGKESKDAVLHLFDICPLKNFKEGLWKKPQTTRS
MLVKDWVTKNSTFLKHVQTLDWEDVDLDTTKGQMRFIELNKEAVEGGYEGVMIKNPNAWYECKRTHSWLKAKPFIEVTLR
VVAIEEGTGRNEGRLGAILVEGEDDKYNYRLNCGSGFSDSQREEYWSERDQIIGQLVEIRADARTKSQDAETFSLRFPRF
KCFRGFEPGQKI
>Mature_412_residues
MKKGLNDFFDGIRMALDPLVTFGVKQVPEKVEETSNKGCKWSDFKGLTTQLIQRELTGYAARDAIKSVMNSATKEQWNGF
YRRVLIKDLRCGVSEKTINKVAKKFPQYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRNNKVEMFSRNGK
QFHNFGHIIAEIEKVLEKHPDPQDLVLDGEVMSANFQDLMKQVHRKDGKESKDAVLHLFDICPLKNFKEGLWKKPQTTRS
MLVKDWVTKNSTFLKHVQTLDWEDVDLDTTKGQMRFIELNKEAVEGGYEGVMIKNPNAWYECKRTHSWLKAKPFIEVTLR
VVAIEEGTGRNEGRLGAILVEGEDDKYNYRLNCGSGFSDSQREEYWSERDQIIGQLVEIRADARTKSQDAETFSLRFPRF
KCFRGFEPGQKI

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022865
- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 47464; Mature: 47464

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS00697 DNA_LIGASE_A1 ; PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGLNDFFDGIRMALDPLVTFGVKQVPEKVEETSNKGCKWSDFKGLTTQLIQRELTGYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
ARDAIKSVMNSATKEQWNGFYRRVLIKDLRCGVSEKTINKVAKKFPQYAIPIFSCPLAHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHCCCCCCC
SANHEKKMIGKKQIEIKLDGVRVLTIIRNNKVEMFSRNGKQFHNFGHIIAEIEKVLEKHP
CCCHHHHHCCCEEEEEEECCEEEEEEEECCCEEEHHCCCHHHHHHHHHHHHHHHHHHHCC
DPQDLVLDGEVMSANFQDLMKQVHRKDGKESKDAVLHLFDICPLKNFKEGLWKKPQTTRS
CCCCEEECCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHH
MLVKDWVTKNSTFLKHVQTLDWEDVDLDTTKGQMRFIELNKEAVEGGYEGVMIKNPNAWY
HHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHCCCCCEEEEECCCCHH
ECKRTHSWLKAKPFIEVTLRVVAIEEGTGRNEGRLGAILVEGEDDKYNYRLNCGSGFSDS
HHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCH
QREEYWSERDQIIGQLVEIRADARTKSQDAETFSLRFPRFKCFRGFEPGQKI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHCCCCCCCCC
>Mature Secondary Structure
MKKGLNDFFDGIRMALDPLVTFGVKQVPEKVEETSNKGCKWSDFKGLTTQLIQRELTGYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
ARDAIKSVMNSATKEQWNGFYRRVLIKDLRCGVSEKTINKVAKKFPQYAIPIFSCPLAHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHCCCCCCC
SANHEKKMIGKKQIEIKLDGVRVLTIIRNNKVEMFSRNGKQFHNFGHIIAEIEKVLEKHP
CCCHHHHHCCCEEEEEEECCEEEEEEEECCCEEEHHCCCHHHHHHHHHHHHHHHHHHHCC
DPQDLVLDGEVMSANFQDLMKQVHRKDGKESKDAVLHLFDICPLKNFKEGLWKKPQTTRS
CCCCEEECCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHH
MLVKDWVTKNSTFLKHVQTLDWEDVDLDTTKGQMRFIELNKEAVEGGYEGVMIKNPNAWY
HHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHCCCCCEEEEECCCCHH
ECKRTHSWLKAKPFIEVTLRVVAIEEGTGRNEGRLGAILVEGEDDKYNYRLNCGSGFSDS
HHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCH
QREEYWSERDQIIGQLVEIRADARTKSQDAETFSLRFPRFKCFRGFEPGQKI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]