Click here to switch to the map view.

The map label for this gene is infC

Identifier: 123967058

GI number: 123967058

Start: 1608102

End: 1608689

Strand: Direct

Name: infC

Synonym: P9515_18251

Alternate gene names: 123967058

Gene position: 1608102-1608689 (Clockwise)

Preceding gene: 123967057

Following gene: 123967059

Centisome position: 94.36

GC content: 33.67

Gene sequence:

>588_bases
ATGCCACCACGTCCACGCTTTGATCGCCGAGCTCCCGTTAGAGAGCTCCCAAATATTAACGAAAGAATAAAATACCCTCA
ATTAAGAGTTGTTGATTCAGATGGAAAACAATTAGGAGTAATAGATAGAATCAAAGCATTAGAAATTGCTAATCAGAGAG
AGCTAGACCTAGTTTTAGTCAGCGAAAAAGCTAATCCACCTGTTTGTAGGATTATGGATTACGGAAAATATAAATTTGAG
CAAGAAAAGAAAGCAAAAGAAGCAAGAAAAAAATCTCACCAAACTGAAGTTAAAGAAGTAAAAATGAGATATAAGATTGA
TAAGCATGACTATGACGTAAGAATAGGGCAAGCTGTTAGATTTTTAAAAGCAGGCGATAAAGTCAAATGTACTGTAATTT
TTAGAGGCAGAGAAATTCAACACTCAAATTTAGCCGAAACACTTCTTTTAAGAATGGCTAATGATTTAGAAGAGCAATCA
GAGGTTCAACAAAGGCCAAAAAGAGAAGGTAGAAACATGATTATGTTTTTAAGTCCCCGAAAAACACCTTTAATTAAAAA
AGAAGAAGATGCAAAAGAAAATAATTAA

Upstream 100 bases:

>100_bases
CCTACTAAAAGATGCAATAATTAAGATAGAGTATGCTTTAGGTTAACTTTATAAAGTATTAGATCATGTTCATCATCAAA
AAATCATTTTAAGAAACTGA

Downstream 100 bases:

>100_bases
TCTACAAGAAATTCACCCAAAGATTATGACAGATGTTAAAGTGCCACCTAAGGTAATTTAAGAACTAAATTAGGTATTTT
CTAAAGTGAGATTCCATATT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MPPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRIKALEIANQRELDLVLVSEKANPPVCRIMDYGKYKFE
QEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQAVRFLKAGDKVKCTVIFRGREIQHSNLAETLLLRMANDLEEQS
EVQQRPKREGRNMIMFLSPRKTPLIKKEEDAKENN

Sequences:

>Translated_195_residues
MPPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRIKALEIANQRELDLVLVSEKANPPVCRIMDYGKYKFE
QEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQAVRFLKAGDKVKCTVIFRGREIQHSNLAETLLLRMANDLEEQS
EVQQRPKREGRNMIMFLSPRKTPLIKKEEDAKENN
>Mature_194_residues
PPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRIKALEIANQRELDLVLVSEKANPPVCRIMDYGKYKFEQ
EKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQAVRFLKAGDKVKCTVIFRGREIQHSNLAETLLLRMANDLEEQSE
VQQRPKREGRNMIMFLSPRKTPLIKKEEDAKENN

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=167, Percent_Identity=45.5089820359281, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_PROM5 (A2BZ21)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001012139.1
- ProteinModelPortal:   A2BZ21
- STRING:   A2BZ21
- GeneID:   4719994
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_18251
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   FDRRAPV
- ProtClustDB:   PRK00028
- BioCyc:   PMAR167542:P9515ORF_1906-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 22965; Mature: 22834

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRIKALEIANQRELDLVLV
CCCCCCCCCCCCHHHCCCCHHHCCCCEEEEECCCCCEECHHHHHHHHHHCCCCCEEEEEE
SEKANPPVCRIMDYGKYKFEQEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQAVR
ECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEHHHHHH
FLKAGDKVKCTVIFRGREIQHSNLAETLLLRMANDLEEQSEVQQRPKREGRNMIMFLSPR
HHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KTPLIKKEEDAKENN
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
PPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRIKALEIANQRELDLVLV
CCCCCCCCCCCHHHCCCCHHHCCCCEEEEECCCCCEECHHHHHHHHHHCCCCCEEEEEE
SEKANPPVCRIMDYGKYKFEQEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQAVR
ECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEHHHHHH
FLKAGDKVKCTVIFRGREIQHSNLAETLLLRMANDLEEQSEVQQRPKREGRNMIMFLSPR
HHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KTPLIKKEEDAKENN
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA