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The map label for this gene is tatD [C]

Identifier: 123966899

GI number: 123966899

Start: 1460986

End: 1461780

Strand: Reverse

Name: tatD [C]

Synonym: P9515_16661

Alternate gene names: 123966899

Gene position: 1461780-1460986 (Counterclockwise)

Preceding gene: 123966900

Following gene: 123966898

Centisome position: 85.78

GC content: 34.34

Gene sequence:

>795_bases
ATGAGTGATATTGAACTCATAGATTCTCATTGTCATTTGATATTCGAAAACTTTGAAAAAGACCTTGAAGAAGTCGTTTC
AAGATCGCGTTCAATAGGTGTTAAAAAACTGCTACACGCTTGTTGTGAATTGTCAGAAATTCCTAAGTTACAGAAAATAT
CCCAAAAATTTGATGAACTATATTACTCAGTTGGTTTACATCCCCTAGAAGCTAACAAATGGGAATGTCAATCTAAATCT
ATTCTGAAAATGGCAGCCCAAAGGGATTCAAGAGTTGTTGCTATTGGTGAATTAGGTTTGGATTTTTTTAAAAGTGATAA
TACAAATAAACAGATAGAGGCCCTTCTACCACAAATGCATTTAGCCTATGAACTTGAATTGCCTGTAATTATCCATTGCA
GAGAAGCTGCAAATGAGATGATAAAAATATGTAATAAGCTATCTAACCAAGGTAAATGTCCCAAAGGAGTACTACATTGT
TGGAGCGGTACTCCGGATGAGATGAGGAAATTTTTAGATCTTGGATTCTATATTAGTTTTAGCGGGATAGTTACATTCCC
AAAAGCACATGAAATTCATGAATGCGCAAGAATTGTCCCCAGTGATAGATATTTGATAGAGACAGATTCACCATTTTTAG
CTCCTGTCCCATACAGAGGTAAAAGAAATGAACCCGCTTTTGTGAAAAGTGTGGCAAAGTACATTGCAAATTTAAGATCT
TCGGAATTGAAAAATATTGCTAAAGAGTCATATAGGAATGCTGAAGATTTGTTTAAATTTGACTTGATAAAGTAA

Upstream 100 bases:

>100_bases
GTCAAAAAAAATGTTCTCCATAAGAATAACGGTGCTAATAAGAAATCAAAAATCAATAAATTAGTTAAAAATTTTCTTAC
AAGCAAGTAAGTAAGTAAAT

Downstream 100 bases:

>100_bases
CACTAAACCTGTTAGTATTAAAAATTACTGGAAATTTTTCTTAATTATTAGTAATAAGCTTGTTTAAAGAGTGGTTTTAT
TATCTTCATCTTTAATCATA

Product: TatD family deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSDIELIDSHCHLIFENFEKDLEEVVSRSRSIGVKKLLHACCELSEIPKLQKISQKFDELYYSVGLHPLEANKWECQSKS
ILKMAAQRDSRVVAIGELGLDFFKSDNTNKQIEALLPQMHLAYELELPVIIHCREAANEMIKICNKLSNQGKCPKGVLHC
WSGTPDEMRKFLDLGFYISFSGIVTFPKAHEIHECARIVPSDRYLIETDSPFLAPVPYRGKRNEPAFVKSVAKYIANLRS
SELKNIAKESYRNAEDLFKFDLIK

Sequences:

>Translated_264_residues
MSDIELIDSHCHLIFENFEKDLEEVVSRSRSIGVKKLLHACCELSEIPKLQKISQKFDELYYSVGLHPLEANKWECQSKS
ILKMAAQRDSRVVAIGELGLDFFKSDNTNKQIEALLPQMHLAYELELPVIIHCREAANEMIKICNKLSNQGKCPKGVLHC
WSGTPDEMRKFLDLGFYISFSGIVTFPKAHEIHECARIVPSDRYLIETDSPFLAPVPYRGKRNEPAFVKSVAKYIANLRS
SELKNIAKESYRNAEDLFKFDLIK
>Mature_263_residues
SDIELIDSHCHLIFENFEKDLEEVVSRSRSIGVKKLLHACCELSEIPKLQKISQKFDELYYSVGLHPLEANKWECQSKSI
LKMAAQRDSRVVAIGELGLDFFKSDNTNKQIEALLPQMHLAYELELPVIIHCREAANEMIKICNKLSNQGKCPKGVLHCW
SGTPDEMRKFLDLGFYISFSGIVTFPKAHEIHECARIVPSDRYLIETDSPFLAPVPYRGKRNEPAFVKSVAKYIANLRSS
ELKNIAKESYRNAEDLFKFDLIK

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=287, Percent_Identity=27.1777003484321, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI110349730, Length=270, Percent_Identity=28.5185185185185, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI110349734, Length=270, Percent_Identity=28.5185185185185, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI226061853, Length=278, Percent_Identity=29.136690647482, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI226061614, Length=258, Percent_Identity=26.7441860465116, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI225903439, Length=235, Percent_Identity=26.8085106382979, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI226061595, Length=235, Percent_Identity=29.3617021276596, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI225903424, Length=225, Percent_Identity=27.5555555555556, Blast_Score=78, Evalue=9e-15,
Organism=Escherichia coli, GI1787342, Length=262, Percent_Identity=38.9312977099237, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI48994985, Length=260, Percent_Identity=32.3076923076923, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=30.5882352941176, Blast_Score=128, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17559024, Length=299, Percent_Identity=28.7625418060201, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI71980746, Length=268, Percent_Identity=29.4776119402985, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17565396, Length=220, Percent_Identity=25, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24648690, Length=293, Percent_Identity=29.3515358361775, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI221330018, Length=281, Percent_Identity=25.9786476868327, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24586117, Length=281, Percent_Identity=25.9786476868327, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30223; Mature: 30092

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIELIDSHCHLIFENFEKDLEEVVSRSRSIGVKKLLHACCELSEIPKLQKISQKFDEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHH
YYSVGLHPLEANKWECQSKSILKMAAQRDSRVVAIGELGLDFFKSDNTNKQIEALLPQMH
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEHHHCHHHHCCCCCCHHHHHHHHHHH
LAYELELPVIIHCREAANEMIKICNKLSNQGKCPKGVLHCWSGTPDEMRKFLDLGFYISF
HHEEECCCEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHEEEE
SGIVTFPKAHEIHECARIVPSDRYLIETDSPFLAPVPYRGKRNEPAFVKSVAKYIANLRS
CCEEECCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SELKNIAKESYRNAEDLFKFDLIK
HHHHHHHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure 
SDIELIDSHCHLIFENFEKDLEEVVSRSRSIGVKKLLHACCELSEIPKLQKISQKFDEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHH
YYSVGLHPLEANKWECQSKSILKMAAQRDSRVVAIGELGLDFFKSDNTNKQIEALLPQMH
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEHHHCHHHHCCCCCCHHHHHHHHHHH
LAYELELPVIIHCREAANEMIKICNKLSNQGKCPKGVLHCWSGTPDEMRKFLDLGFYISF
HHEEECCCEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHEEEE
SGIVTFPKAHEIHECARIVPSDRYLIETDSPFLAPVPYRGKRNEPAFVKSVAKYIANLRS
CCEEECCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SELKNIAKESYRNAEDLFKFDLIK
HHHHHHHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]