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The map label for this gene is rpoC1 [H]

Identifier: 123966897

GI number: 123966897

Start: 1455510

End: 1457414

Strand: Reverse

Name: rpoC1 [H]

Synonym: P9515_16641

Alternate gene names: 123966897

Gene position: 1457414-1455510 (Counterclockwise)

Preceding gene: 123966898

Following gene: 123966896

Centisome position: 85.52

GC content: 35.96

Gene sequence:

>1905_bases
ATGACTAACAGCAACTTAAGAACAGAAAACCATTTTGATTACGTCAAGATTTCTATTGCCTCACCACAAAGAATTATGGA
TTGGGGGCAAAGGACCTTACCAAATGGACAAGTAGTAGGAGAGGTTACTAAACCCGAGACAATCAACTATAGAACCTTAA
AACCAGAAATGGACGGTCTTTTTTGTGAAAAAATATTTGGACCATCTAAAGATTGGGAATGTCACTGCGGTAAATATAAA
AGAGTCAGACATCGTGGAATTGTTTGCGAGAGATGTGGGGTAGAAGTAACTGAAAGTAGAGTAAGAAGACATAGAATGGG
TTACATAAAATTGGCAGCCCCAGTTTCCCATGTTTGGTATTTAAAGGGTATTCCCAGTTATGTGGCAATTCTTCTAGATA
TCCCGCTTAGAGATGTCGAACAGATAGTTTATTTCAATTGTTATGTTGTTTTAGATGTTGGTGATCATAAAGATCTTAAA
TATAAGCAACTTCTTACTGAAGACGAATGGTTAGAGATAGAGGATGAAATTTATGCAGAAGATTCAACGATTGAAAATGA
ACCATTTGTGGGTATAGGTGCAGAAGCTCTTAAGCAATTATTAGAGGATCTTGATTTAAATCAGATTGCCGAAGAACTTA
GAGAAGAAATCACAAACAGTAAAGGTCAAAAAAGAGCAAAACTTATTAAAAGAATAAGAGTAATTGATAATTTCATAGCA
ACAAATGCGAAGCCCGAATGGATGGTATTAGATGCTATTCCTGTCATTCCTCCTGATCTTAGACCAATGGTTCAGCTCGA
TGGTGGAAGGTTCGCGACATCTGATCTTAATGATCTTTATAGAAGAGTTATCAATAGAAACAATAGGCTAGCAAGGCTTC
AAGAAATTTTAGCTCCTGAAATCATTGTTAGAAATGAAAAAAGAATGTTGCAAGAAGCCGTTGATGCACTTATTGATAAT
GGAAGAAGAGGAAGAACAGTTGTTGGTGCAAATAATAGAGCTTTAAAATCTCTTAGCGATATCATCGAGGGCAAGCAAGG
CAGATTTAGACAGAATTTACTTGGTAAACGTGTTGATTATTCTGGAAGGTCTGTCATAGTTGTTGGCCCAAAGTTAAAGA
TGCATCAATGCGGACTCCCTAAAGAGATGGCTATTGAGCTTTTTCAACCTTTCGTGATACATAGATTAATACGTCAAAAT
ATCGTCAATAATATAAAAGCTGCCAAAAAATTAATACAAAAAGCAGATGATGAAGTCATGCAAGTACTTCAAGAAGTTAT
TGAAGGACATCCCATACTTTTAAATAGAGCTCCAACTCTTCATAGGTTAGGAATTCAGGCTTTTGAACCTAAATTAGTAG
GTGGTAGAGCTATTCAACTACATCCACTTGTATGTCCTGCATTTAATGCTGACTTTGATGGAGATCAAATGGCAGTTCAC
GTTCCTTTAGCATTAGAAGCTCAAACAGAGGCGCGTATGCTTATGCTAGCTAGTAATAACATTCTCTCACCAGCAACAGG
AGAACCAATCGTAACTCCTTCACAAGATATGGTTTTAGGTTCTTATTATTTAACCGCACTGCAACCAAATTTCAAAAAAC
CAAATTTTGGTGATAATCAAAGAACTTACGCCTCACTAGAAGATGTAATTTTTGCTTTTGAAGATAAAAGAGTTGGTTTA
CATGAGTGGGTTTGGTTAAGGTTTAACGGCGAAGTTGATGATGATGAAGAATCTAAGACGCCACAAGAAACTAAAGAATT
GGAAGATGGCTCCAAATTAGAAATTTGGAATTTTAGAAGAGATAGATTTGATTCCCAAAATAATCTAATAAGTAGATTTA
TTTTAACAACAGTCGGAAGGGTGGTTATGAATCATACGATCATTGATTCTGTCTCCAAAACGTGA

Upstream 100 bases:

>100_bases
GGAATACTCCTTCGAGGCCTACCTATGAATCTCTAGGAACCTCTGAATATGAGGAAGATTAAATACTTTATCAAAACTTT
CTAATTTAAATCTCCTAAAA

Downstream 100 bases:

>100_bases
TCCTTTAAAAAAAAAACTAATTATTTATCCATAAAACAATGACATCATCTAAACCAAAAAAAAGTTCAAGAGTACGTAAA
ACTTCAAAAAATTCAAAAAA

Product: DNA-directed RNA polymerase subunit gamma

Products: NA

Alternate protein names: RNAP subunit gamma; RNA polymerase subunit gamma; Transcriptase subunit gamma [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MTNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYK
RVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWYLKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDVGDHKDLK
YKQLLTEDEWLEIEDEIYAEDSTIENEPFVGIGAEALKQLLEDLDLNQIAEELREEITNSKGQKRAKLIKRIRVIDNFIA
TNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDN
GRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQN
IVNNIKAAKKLIQKADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVH
VPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNFKKPNFGDNQRTYASLEDVIFAFEDKRVGL
HEWVWLRFNGEVDDDEESKTPQETKELEDGSKLEIWNFRRDRFDSQNNLISRFILTTVGRVVMNHTIIDSVSKT

Sequences:

>Translated_634_residues
MTNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYK
RVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWYLKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDVGDHKDLK
YKQLLTEDEWLEIEDEIYAEDSTIENEPFVGIGAEALKQLLEDLDLNQIAEELREEITNSKGQKRAKLIKRIRVIDNFIA
TNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDN
GRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQN
IVNNIKAAKKLIQKADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVH
VPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNFKKPNFGDNQRTYASLEDVIFAFEDKRVGL
HEWVWLRFNGEVDDDEESKTPQETKELEDGSKLEIWNFRRDRFDSQNNLISRFILTTVGRVVMNHTIIDSVSKT
>Mature_633_residues
TNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYKR
VRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWYLKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDVGDHKDLKY
KQLLTEDEWLEIEDEIYAEDSTIENEPFVGIGAEALKQLLEDLDLNQIAEELREEITNSKGQKRAKLIKRIRVIDNFIAT
NAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNG
RRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNI
VNNIKAAKKLIQKADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVHV
PLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNFKKPNFGDNQRTYASLEDVIFAFEDKRVGLH
EWVWLRFNGEVDDDEESKTPQETKELEDGSKLEIWNFRRDRFDSQNNLISRFILTTVGRVVMNHTIIDSVSKT

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=492, Percent_Identity=26.6260162601626, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI39725938, Length=321, Percent_Identity=28.9719626168224, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI103471997, Length=234, Percent_Identity=29.4871794871795, Blast_Score=97, Evalue=6e-20,
Organism=Escherichia coli, GI2367335, Length=524, Percent_Identity=62.2137404580153, Blast_Score=694, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=308, Percent_Identity=32.1428571428571, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71987878, Length=305, Percent_Identity=30.8196721311475, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71998295, Length=347, Percent_Identity=24.4956772334294, Blast_Score=96, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320061, Length=497, Percent_Identity=27.1629778672032, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6324690, Length=227, Percent_Identity=36.1233480176211, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324917, Length=301, Percent_Identity=24.5847176079734, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17530899, Length=310, Percent_Identity=29.6774193548387, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360912, Length=503, Percent_Identity=26.2425447316103, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17647875, Length=348, Percent_Identity=27.5862068965517, Blast_Score=109, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR012755 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 72500; Mature: 72369

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGL
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCH
FCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWY
HHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCEEEEECCHHHHHH
LKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDVGDHKDLKYKQLLTEDEWLEIEDEIYAE
HCCHHHHHHHHHHCCHHHHHHEEEEEEEEEEECCCCCCCHHHHHCCCCCCEEECHHHCCC
DSTIENEPFVGIGAEALKQLLEDLDLNQIAEELREEITNSKGQKRAKLIKRIRVIDNFIA
CCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPE
CCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCH
IIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDY
HEECCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQKADDEVM
CCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVH
HHHHHHHCCCCEEEECCCCHHHHCCHHCCCEEECCEEEEEECEECCCCCCCCCCCCEEEE
VPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNFKKPNFGDNQ
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEHHHHHEEECCCCCCCCCCCCC
RTYASLEDVIFAFEDKRVGLHEWVWLRFNGEVDDDEESKTPQETKELEDGSKLEIWNFRR
HHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHCCCCCEEEEEECHH
DRFDSQNNLISRFILTTVGRVVMNHTIIDSVSKT
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGL
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCH
FCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWY
HHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCEEEEECCHHHHHH
LKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDVGDHKDLKYKQLLTEDEWLEIEDEIYAE
HCCHHHHHHHHHHCCHHHHHHEEEEEEEEEEECCCCCCCHHHHHCCCCCCEEECHHHCCC
DSTIENEPFVGIGAEALKQLLEDLDLNQIAEELREEITNSKGQKRAKLIKRIRVIDNFIA
CCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPE
CCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCH
IIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDY
HEECCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQKADDEVM
CCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVH
HHHHHHHCCCCEEEECCCCHHHHCCHHCCCEEECCEEEEEECEECCCCCCCCCCCCEEEE
VPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNFKKPNFGDNQ
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEHHHHHEEECCCCCCCCCCCCC
RTYASLEDVIFAFEDKRVGLHEWVWLRFNGEVDDDEESKTPQETKELEDGSKLEIWNFRR
HHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHCCCCCEEEEEECHH
DRFDSQNNLISRFILTTVGRVVMNHTIIDSVSKT
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA