Click here to switch to the map view.

The map label for this gene is des [H]

Identifier: 123966785

GI number: 123966785

Start: 1371646

End: 1372752

Strand: Direct

Name: des [H]

Synonym: P9515_15521

Alternate gene names: 123966785

Gene position: 1371646-1372752 (Clockwise)

Preceding gene: 123966784

Following gene: 123966787

Centisome position: 80.49

GC content: 27.1

Gene sequence:

>1107_bases
ATGAATAAAATCAAAAGATCTGATTTTATATTAAAGCCATTTCTAAAAAGGAATAATTTTAAAGCGTTCTATCAGCTAAT
AACTACTCTCGTACCAATAATCGCTATTTGGATTATTGTTTCTAAAATTGTATATTCTCCTCTTTTGCCAATTGCAAAAG
GGATTTTATTGATTCCCATTCTCTTTCTTCTTACCCTATTATCTTCAAGAACATTCTCATTAATGCATGATTGTGGACAT
AATTCCTTATTTGAAAAACGTTCTTTGAATAACTTTTTTGGTTTTTTTCTAGGTTTGTTAAATGGAATACCTCATAAACC
TTGGGCTAATGATCATGCATTCCACCATCGAAATAATGGGAATTGGGAAATTTATAAAGGTCCTGTAGATGTGTTAAGCC
TAGAAGATTATGAATCTCTTACTAAAAGAGAAAAACTTATTTATAAAATTAGTAGACATTGGTTAATGCTTTTACCAGGA
GGTTTCTTTTATTTGGTTATTAAAGCAAGATTAGGACTTATTTTGATTATCTTTAATTTTATTAAATCCTTGATGATAGA
AAGTTTTATTAAAATTAAAGAAAGAAATTATTCTCAACTTTTAAACATTAAATCAAGAATTAAACCTCCTTTCTCTGATT
ATGGAGATAATTTTGATGAATTATTTGATCTGATTGCTAACAATATTATTGTTATAACTGGTTGGATAATTATGTGTAAG
TGGTTAGGAGCCGTATTTTTCTTAACTTTTTATTCGATAATATTAACTTTTTCAGCAGCAATTTTCATATGTATCTTTTT
CATACAACATAACTATGAAAATGCATATGCGAGTAATACAAAAAACTGGGATATTGTCGAAGGTGCAATTTTTGGAAGCA
GCAATTTAGATATACCAAATTGGTTAAATTGGTTCTTAGCTGATATTTCTTTTCACAGCATTCATCATCTATCAGAAAGA
ATCCCTAATTACAATTTAAGAGCTTGTCATAAAGCAAATATACATTTACTAAAAAAGTCAAAATTTCTTAAATTAAGTGA
CTTCCCTAATTGTTTTAAATATATTATTTGGGACAGTAAAAATGAAAATCTAATCCCAATTAATTAA

Upstream 100 bases:

>100_bases
TGGTTATAGCCATAGTTTTCGTATATCTTAAATTTATAACTTTACCACGATAATTTTTAACTCGACTATCCTATCTATAG
AGAATCAAAGAAAAATTTAT

Downstream 100 bases:

>100_bases
AACTAGCTGAATCTTCTTCTCATTTTCCTTTTTAGAGGAACATTACTGTAAGCGTGGGCTCCAATAGATGGAGGCAAGTC
GTTTTTAACAGGATGAATAA

Product: Fatty acid desaturase, type 2

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MNKIKRSDFILKPFLKRNNFKAFYQLITTLVPIIAIWIIVSKIVYSPLLPIAKGILLIPILFLLTLLSSRTFSLMHDCGH
NSLFEKRSLNNFFGFFLGLLNGIPHKPWANDHAFHHRNNGNWEIYKGPVDVLSLEDYESLTKREKLIYKISRHWLMLLPG
GFFYLVIKARLGLILIIFNFIKSLMIESFIKIKERNYSQLLNIKSRIKPPFSDYGDNFDELFDLIANNIIVITGWIIMCK
WLGAVFFLTFYSIILTFSAAIFICIFFIQHNYENAYASNTKNWDIVEGAIFGSSNLDIPNWLNWFLADISFHSIHHLSER
IPNYNLRACHKANIHLLKKSKFLKLSDFPNCFKYIIWDSKNENLIPIN

Sequences:

>Translated_368_residues
MNKIKRSDFILKPFLKRNNFKAFYQLITTLVPIIAIWIIVSKIVYSPLLPIAKGILLIPILFLLTLLSSRTFSLMHDCGH
NSLFEKRSLNNFFGFFLGLLNGIPHKPWANDHAFHHRNNGNWEIYKGPVDVLSLEDYESLTKREKLIYKISRHWLMLLPG
GFFYLVIKARLGLILIIFNFIKSLMIESFIKIKERNYSQLLNIKSRIKPPFSDYGDNFDELFDLIANNIIVITGWIIMCK
WLGAVFFLTFYSIILTFSAAIFICIFFIQHNYENAYASNTKNWDIVEGAIFGSSNLDIPNWLNWFLADISFHSIHHLSER
IPNYNLRACHKANIHLLKKSKFLKLSDFPNCFKYIIWDSKNENLIPIN
>Mature_368_residues
MNKIKRSDFILKPFLKRNNFKAFYQLITTLVPIIAIWIIVSKIVYSPLLPIAKGILLIPILFLLTLLSSRTFSLMHDCGH
NSLFEKRSLNNFFGFFLGLLNGIPHKPWANDHAFHHRNNGNWEIYKGPVDVLSLEDYESLTKREKLIYKISRHWLMLLPG
GFFYLVIKARLGLILIIFNFIKSLMIESFIKIKERNYSQLLNIKSRIKPPFSDYGDNFDELFDLIANNIIVITGWIIMCK
WLGAVFFLTFYSIILTFSAAIFICIFFIQHNYENAYASNTKNWDIVEGAIFGSSNLDIPNWLNWFLADISFHSIHHLSER
IPNYNLRACHKANIHLLKKSKFLKLSDFPNCFKYIIWDSKNENLIPIN

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 43051; Mature: 43051

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIKRSDFILKPFLKRNNFKAFYQLITTLVPIIAIWIIVSKIVYSPLLPIAKGILLIPI
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLLTLLSSRTFSLMHDCGHNSLFEKRSLNNFFGFFLGLLNGIPHKPWANDHAFHHRNNG
HHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCC
NWEIYKGPVDVLSLEDYESLTKREKLIYKISRHWLMLLPGGFFYLVIKARLGLILIIFNF
CEEEEECCCCEEECHHHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHHH
IKSLMIESFIKIKERNYSQLLNIKSRIKPPFSDYGDNFDELFDLIANNIIVITGWIIMCK
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHCCEEEEHHHHHHHH
WLGAVFFLTFYSIILTFSAAIFICIFFIQHNYENAYASNTKNWDIVEGAIFGSSNLDIPN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEECCCCCCCHH
WLNWFLADISFHSIHHLSERIPNYNLRACHKANIHLLKKSKFLKLSDFPNCFKYIIWDSK
HHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEEECCCCEECCCCCHHHHHEEECCC
NENLIPIN
CCCEECCC
>Mature Secondary Structure
MNKIKRSDFILKPFLKRNNFKAFYQLITTLVPIIAIWIIVSKIVYSPLLPIAKGILLIPI
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLLTLLSSRTFSLMHDCGHNSLFEKRSLNNFFGFFLGLLNGIPHKPWANDHAFHHRNNG
HHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCC
NWEIYKGPVDVLSLEDYESLTKREKLIYKISRHWLMLLPGGFFYLVIKARLGLILIIFNF
CEEEEECCCCEEECHHHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHHH
IKSLMIESFIKIKERNYSQLLNIKSRIKPPFSDYGDNFDELFDLIANNIIVITGWIIMCK
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHCCEEEEHHHHHHHH
WLGAVFFLTFYSIILTFSAAIFICIFFIQHNYENAYASNTKNWDIVEGAIFGSSNLDIPN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEECCCCCCCHH
WLNWFLADISFHSIHHLSERIPNYNLRACHKANIHLLKKSKFLKLSDFPNCFKYIIWDSK
HHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEEECCCCEECCCCCHHHHHEEECCC
NENLIPIN
CCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]